Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Low tension recruits the yeast Aurora B protein Ipl1 to centromeres in metaphase.

Edgerton, Heather D; Mukherjee, Soumya; Johansson, Marnie; Bachant, Jeff; Gardner, Melissa K; Clarke, Duncan J.

J Cell Sci ; 136(16)2023 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-37519149

2.

MCPH1 is essential for cellular adaptation to the G₂-phase decatenation checkpoint.

Arroyo, María; Kuriyama, Ryoko; Guerrero, Israel; Keifenheim, Daniel; Cañuelo, Ana; Calahorra, Jesús; Sánchez, Antonio; Clarke, Duncan J; Marchal, J Alberto.

FASEB J ; 33(7): 8363-8374, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30964711

3.

Cell cycle checkpoints and cell surface damage.

Johansson, Marnie; Clarke, Duncan J.

Bioessays ; 44(7): e2200079, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35478411

4.

Non-Catalytic Roles of the Topoisomerase IIα C-Terminal Domain.

Clarke, Duncan J; Azuma, Yoshiaki.

Int J Mol Sci ; 18(11)2017 Nov 17.

Artigo em Inglês | MEDLINE | ID: mdl-29149026

5.

Direct monitoring of the strand passage reaction of DNA topoisomerase II triggers checkpoint activation.

Furniss, Katherine L; Tsai, Hung-Ji; Byl, Jo Ann W; Lane, Andrew B; Vas, Amit C; Hsu, Wei-Shan; Osheroff, Neil; Clarke, Duncan J.

PLoS Genet ; 9(10): e1003832, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24098144

6.

Cell surface damage activates a cell cycle checkpoint (comment on DOI: 10.1002/bies.201600210).

Clarke, Duncan J.

Bioessays ; 39(4)2017 04.

Artigo em Inglês | MEDLINE | ID: mdl-28266055

7.

Genome instability: does genetic diversity amplification drive tumorigenesis?

Lane, Andrew B; Clarke, Duncan J.

Bioessays ; 34(11): 963-72, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22948965

8.

Cell cycle responses to Topoisomerase II inhibition: Molecular mechanisms and clinical implications.

Soliman, Tanya N; Keifenheim, Daniel; Parker, Peter J; Clarke, Duncan J.

J Cell Biol ; 222(12)2023 12 04.

Artigo em Inglês | MEDLINE | ID: mdl-37955972

9.

Methylated histones on mitotic chromosomes promote topoisomerase IIα function for high fidelity chromosome segregation.

Sundararajan, Sanjana; Park, Hyewon; Kawano, Shinji; Johansson, Marnie; Lama, Bunu; Saito-Fujita, Tomoko; Saitoh, Noriko; Arnaoutov, Alexei; Dasso, Mary; Wang, Zhengqiang; Keifenheim, Daniel; Clarke, Duncan J; Azuma, Yoshiaki.

iScience ; 26(5): 106743, 2023 May 19.

Artigo em Inglês | MEDLINE | ID: mdl-37197327

10.

Robust microtubule dynamics facilitate low-tension kinetochore detachment in metaphase.

Parmar, Sneha; Gonzalez, Samuel J; Heckel, Julia M; Mukherjee, Soumya; McClellan, Mark; Clarke, Duncan J; Johansson, Marnie; Tank, Damien; Geisness, Athena; Wood, David K; Gardner, Melissa K.

J Cell Biol ; 222(8)2023 08 07.

Artigo em Inglês | MEDLINE | ID: mdl-37166419

11.

Decatenation: fixing your knots.

Clarke, Duncan J.

Blood ; 114(9): 1721-2, 2009 Aug 27.

Artigo em Inglês | MEDLINE | ID: mdl-19713475

12.

S-phase checkpoint controls mitosis via an APC-independent Cdc20p function.

Clarke, Duncan J; Segal, Marisa; Andrews, Catherine A; Rudyak, Stanislav G; Jensen, Sanne; Smith, Karen; Reed, Steven I.

Nat Cell Biol ; 5(10): 928-35, 2003 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-14502293

13.

In vivo analysis of chromosome condensation in Saccharomyces cerevisiae.

Vas, Amit C J; Andrews, Catherine A; Kirkland Matesky, Kathryn; Clarke, Duncan J.

Mol Biol Cell ; 18(2): 557-68, 2007 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-17151360

14.

Mitotic entry upon Topo II catalytic inhibition is controlled by Chk1 and Plk1.

Arroyo, Maria; Cañuelo, Ana; Calahorra, Jesús; Hastert, Florian D; Sánchez, Antonio; Clarke, Duncan J; Marchal, J Alberto.

FEBS J ; 287(22): 4933-4951, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32144855

15.

MCPH1 Lack of Function Enhances Mitotic Cell Sensitivity Caused by Catalytic Inhibitors of Topo II.

Arroyo, María; Sánchez, Antonio; Cañuelo, Ana; Heredia-Molina, Rosalía F; Martínez-Molina, Eduardo; Clarke, Duncan J; Marchal, Juan Alberto.

Genes (Basel) ; 11(4)2020 04 08.

Artigo em Inglês | MEDLINE | ID: mdl-32276518

16.

Topoisomerase II SUMOylation activates a metaphase checkpoint via Haspin and Aurora B kinases.

Pandey, Nootan; Keifenheim, Daniel; Yoshida, Makoto Michael; Hassebroek, Victoria A; Soroka, Caitlin; Azuma, Yoshiaki; Clarke, Duncan J.

J Cell Biol ; 219(1)2020 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-31712254

17.

Cell cycle regulation of condensin Smc4.

Wei-Shan, Hsu; Amit, Vas C; Clarke, Duncan J.

Oncotarget ; 10(3): 263-276, 2019 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-30719224

18.

Kinetochore structure and spindle assembly checkpoint signaling in the budding yeast, Saccharomyces cerevisiae.

Clarke, Duncan J; Bachant, Jeff.

Front Biosci ; 13: 6787-819, 2008 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-18508695

19.

Are tumor cells protected from some anti-cancer drugs by elevated APC/C activity? (comment on DOI: 10.1002/bies.201100094).

Clarke, Duncan J.

Bioessays ; 33(12): 898, 2011 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22045638

20.

Analyzing Mitotic Chromosome Structural Defects After Topoisomerase II Inhibition or Mutation.

Giménez-Abián, Juan F; Lane, Andrew B; Clarke, Duncan J.

Methods Mol Biol ; 1703: 191-215, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-29177744

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Low tension recruits the yeast Aurora B protein Ipl1 to centromeres in metaphase.

MCPH1 is essential for cellular adaptation to the G₂-phase decatenation checkpoint.

Cell cycle checkpoints and cell surface damage.

Non-Catalytic Roles of the Topoisomerase IIα C-Terminal Domain.

Direct monitoring of the strand passage reaction of DNA topoisomerase II triggers checkpoint activation.

Cell surface damage activates a cell cycle checkpoint (comment on DOI: 10.1002/bies.201600210).

Genome instability: does genetic diversity amplification drive tumorigenesis?

Cell cycle responses to Topoisomerase II inhibition: Molecular mechanisms and clinical implications.

Methylated histones on mitotic chromosomes promote topoisomerase IIα function for high fidelity chromosome segregation.

Robust microtubule dynamics facilitate low-tension kinetochore detachment in metaphase.

Decatenation: fixing your knots.

S-phase checkpoint controls mitosis via an APC-independent Cdc20p function.

In vivo analysis of chromosome condensation in Saccharomyces cerevisiae.

Mitotic entry upon Topo II catalytic inhibition is controlled by Chk1 and Plk1.

MCPH1 Lack of Function Enhances Mitotic Cell Sensitivity Caused by Catalytic Inhibitors of Topo II.

Topoisomerase II SUMOylation activates a metaphase checkpoint via Haspin and Aurora B kinases.

Cell cycle regulation of condensin Smc4.

Kinetochore structure and spindle assembly checkpoint signaling in the budding yeast, Saccharomyces cerevisiae.

Are tumor cells protected from some anti-cancer drugs by elevated APC/C activity? (comment on DOI: 10.1002/bies.201100094).

Analyzing Mitotic Chromosome Structural Defects After Topoisomerase II Inhibition or Mutation.