Detalhe da pesquisa
1.
Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses.
Immunity
; 55(3): 512-526.e9, 2022 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35263569
2.
Antibody targeting of E3 ubiquitin ligases for receptor degradation.
Nature
; 610(7930): 182-189, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36131013
3.
Systematic pharmacological analysis of agonistic and antagonistic fibroblast growth factor receptor 1 MAbs reveals a similar unique mode of action.
J Biol Chem
; 299(1): 102729, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36410439
4.
Generation of a Porcine Antibody Fab Fragment Using Protein Engineering to Facilitate the Evaluation of Ocular Sustained Delivery Technology.
Mol Pharm
; 19(5): 1540-1547, 2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35393854
5.
Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development.
J Transl Med
; 19(1): 517, 2021 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34930320
6.
A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants.
Bioorg Chem
; 116: 105376, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34560560
7.
Hyaluronic Acid-Antibody Fragment Bioconjugates for Extended Ocular Pharmacokinetics.
Bioconjug Chem
; 30(11): 2782-2789, 2019 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31553572
8.
Corrigendum to "A novel method to produce synthetic murine CXCL10 for efficient screening of functional variants" [Bioorg. Chem. 116 (2021) 105376].
Bioorg Chem
; 120: 105655, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35134644
9.
Mechanism for neutralizing activity by the anti-CMV gH/gL monoclonal antibody MSL-109.
Proc Natl Acad Sci U S A
; 111(22): 8209-14, 2014 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24843144
10.
Unliganded fibroblast growth factor receptor 1 forms density-independent dimers.
J Biol Chem
; 290(40): 24166-77, 2015 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26272615
11.
The oligomeric state sets GABA(B) receptor signalling efficacy.
EMBO J
; 30(12): 2336-49, 2011 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-21552208
12.
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.
Proc Natl Acad Sci U S A
; 109(14): 5399-404, 2012 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22421438
13.
Up-regulation of GABA(B) receptor signaling by constitutive assembly with the K+ channel tetramerization domain-containing protein 12 (KCTD12).
J Biol Chem
; 288(34): 24848-56, 2013 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23843457
14.
HPK1 citron homology domain regulates phosphorylation of SLP76 and modulates kinase domain interaction dynamics.
Nat Commun
; 15(1): 3725, 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38697971
15.
Stability of GABAB receptor oligomers revealed by dual TR-FRET and drug-induced cell surface targeting.
FASEB J
; 26(8): 3430-9, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22613777
16.
A novel, label-free, pre-equilibrium assay to determine the association and dissociation rate constants of therapeutic antibodies on living cells.
Br J Pharmacol
; 2023 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783572
17.
Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun
; 14(1): 7940, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38040762
18.
Structural basis for HCMV Pentamer receptor recognition and antibody neutralization.
Sci Adv
; 8(10): eabm2536, 2022 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35275719
19.
Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization.
Nat Methods
; 5(6): 561-7, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18488035
20.
Long-Term Stability of Anti-Vascular Endothelial Growth Factor (a-VEGF) Biologics Under Physiologically Relevant Conditions and Its Impact on the Development of Long-Acting Delivery Systems.
J Pharm Sci
; 110(2): 860-870, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33031788