Detalhe da pesquisa
1.
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics.
Genes Dev
; 26(16): 1780-96, 2012 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22855790
2.
p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells.
J Biol Chem
; 289(12): 8067-85, 2014 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24519935
3.
Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling.
Development
; 139(14): 2614-24, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22736245
4.
Expression of Hedgehog ligand and signal transduction components in mutually distinct isocitrate dehydrogenase mutant glioma cells supports a role for paracrine signaling.
J Neurooncol
; 119(2): 243-51, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24867209
5.
TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.
Acta Neuropathol
; 126(6): 917-29, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24174164
6.
Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development.
Proc Natl Acad Sci U S A
; 107(18): 8422-7, 2010 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20400693
7.
A defective response to Hedgehog signaling in disorders of cholesterol biosynthesis.
Nat Genet
; 33(4): 508-13, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12652302
8.
Clustering of dystonia in some pedigrees with autosomal dominant essential tremor suggests the existence of a distinct subtype of essential tremor.
BMC Neurol
; 10: 66, 2010 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-20670416
9.
Prevalence of unilateral tremor in autosomal dominant essential tremor.
Mov Disord
; 24(1): 108-11, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18973247
10.
Positive family history of essential tremor influences the motor phenotype of Parkinson's disease.
Mov Disord
; 24(15): 2285-8, 2009 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19795470
11.
Reappraisal of the role of the DRD3 gene in essential tremor.
Parkinsonism Relat Disord
; 14(6): 471-5, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18316228
12.
Intertumoral Heterogeneity within Medulloblastoma Subgroups.
Cancer Cell
; 31(6): 737-754.e6, 2017 06 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28609654
13.
Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study.
PLoS One
; 10(10): e0141659, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26517124
14.
An in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibition.
Cell Rep
; 11(1): 43-50, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25818300
15.
EAG2 potassium channel with evolutionarily conserved function as a brain tumor target.
Nat Neurosci
; 18(9): 1236-46, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26258683
16.
Primary orthotopic glioma xenografts recapitulate infiltrative growth and isocitrate dehydrogenase I mutation.
J Vis Exp
; (83): e50865, 2014 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-24458098
17.
Cytogenetic prognostication within medulloblastoma subgroups.
J Clin Oncol
; 32(9): 886-96, 2014 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24493713
18.
Cancer stem cells in glioma: challenges and opportunities.
Transl Cancer Res
; 2(5): 429-441, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24634854
19.
Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation.
Cancer Lett
; 328(2): 297-306, 2013 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23063752
20.
Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation.
PLoS One
; 7(4): e35541, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22539980