Detalhe da pesquisa
1.
SM16, an orally active TGF-beta type I receptor inhibitor prevents myofibroblast induction and vascular fibrosis in the rat carotid injury model.
Arterioscler Thromb Vasc Biol
; 28(4): 665-71, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18202322
2.
A novel small-molecule inhibitor of transforming growth factor beta type I receptor kinase (SM16) inhibits murine mesothelioma tumor growth in vivo and prevents tumor recurrence after surgical resection.
Cancer Res
; 67(5): 2351-9, 2007 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17332368
3.
Small molecular inhibitor of transforming growth factor-beta protects against development of radiation-induced lung injury.
Int J Radiat Oncol Biol Phys
; 71(3): 829-37, 2008 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18411002
4.
A phase I clinical trial of single-dose intrapleural IFN-beta gene transfer for malignant pleural mesothelioma and metastatic pleural effusions: high rate of antitumor immune responses.
Clin Cancer Res
; 13(15 Pt 1): 4456-66, 2007 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17671130
5.
Postnatal recapitulation of embryonic hedgehog pathway in response to skeletal muscle ischemia.
Circulation
; 108(4): 479-85, 2003 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-12860919
6.
Systemic blockade of transforming growth factor-beta signaling augments the efficacy of immunogene therapy.
Cancer Res
; 68(24): 10247-56, 2008 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19074893
7.
Down-regulation of p21WAF1 promotes apoptosis in senescent human fibroblasts: involvement of retinoblastoma protein phosphorylation and delay of cellular aging.
J Cell Physiol
; 201(3): 483-91, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15389598
8.
Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI).
Bioorg Med Chem Lett
; 13(24): 4355-9, 2003 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14643325