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1.
Brain Inj ; 29(12): 1439-44, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26305856

RESUMO

OBJECTIVE: The main objective of this study is to determine whether gender affects global mortality and functional outcome after severe traumatic brain injury (TBI). METHODS: This retrospective cohort study included 629 patients with severe TBI (14.9% female) admitted to the ICU of a university hospital. Patients were split into gender groups to study potential differences in global mortality and functional outcome at ICU discharge and 6 months post-trauma using the GOS. The following variables were analysed: age, intracranial injury, injury mechanism, injury severity, factors contributing to secondary brain injury, monitoring level, treatment, complications, length of stay in the ICU and cause of death. RESULTS: No differences were found between gender groups in neuromonitoring level or surgical procedures. Women had higher APACHE II scores, a higher incidence of pre-hospital hypotension, anaemia and transfusion and higher mortality rates in the ICU (OR = 1.74; 95% CI = 1.09-2.77) and 6 months post-trauma (OR = 1.65; 95% CI = 1.02-2.67). There were no significant differences in functional outcome at ICU discharge or 6 months post-injury. The multivariate analysis did not show gender as an independent predictive factor in mortality after severe TBI. CONCLUSION: In this study, gender was not found to be an independent predictor for poorer outcome after severe TBI.


Assuntos
Lesões Encefálicas/mortalidade , Fatores Sexuais , Adulto , Estudos de Coortes , Feminino , Previsões , Escala de Coma de Glasgow , Escala de Resultado de Glasgow , Humanos , Unidades de Terapia Intensiva , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Espanha , Adulto Jovem
2.
Artigo em Inglês | MEDLINE | ID: mdl-38972354

RESUMO

INTRODUCTION: Adequate treatment of acute postoperative pain is one of the quality requirements in ambulatory surgery and its suboptimal management is associated with delayed discharge, unplanned admissions and late admissions after home discharge. The aim of the present study was to learn about the organizational strategy for the management of postoperative pain in ambulatory surgery units (ASU) in Spain. METHODS: A cross-sectional, multicenter study was carried out based on an electronic survey on aspects related to the management of acute postoperative pain in different ASUs in our country. RESULTS: We recruited 133 ASUs of which 85 responded to the questions on the management of postoperative pain. Of the ASUs that responded, 80% had specific protocols for pain management and 37.6% provided preoperative information on the analgesic plan. The assessment of postoperative pain is carried out in 88.2% of the ASUs in the facility and only 56.5% at home. All ASUs use multimodal analgesia protocols; however, 68.2% report the use of opioids for the treatment of moderate to severe pain. Home invasive analgesia strategies are minimally used by the surveyed ASUs. CONCLUSIONS: The DUCMA study highlights that the practice of pain treatment in day surgery remains a challenge in our country and is not always in agreement with national guidelines. The results suggest the need to establish strategies to improve clinical practice and homogenize pain management in ambulatory surgery.

3.
Actas Urol Esp (Engl Ed) ; 47(3): 140-148, 2023 04.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-36462604

RESUMO

INTRODUCTION: Kidney procurement procedure must be carried out following a standardized technique in order to optimize kidney grafts for their subsequent implantation. OBJECTIVES: Review of the available literature on kidney procurement procedure. MATERIAL AND METHODS: Narrative review of the available evidence on deceased donor kidney procurement technique after a search of relevant manuscripts indexed in PubMed, EMBASE and Scielo written in English and Spanish. RESULTS: Deceased donor kidney procurement can be divided into two groups, donation after brain death (DBD) and donation after circulatory death (DCD). Kidney procurement in DBD frequently includes other chest and/or abdominal organs, requiring multidisciplinary surgical coordination. During the harvesting procedure, the renal vascular pedicle must remain intact for subsequent implantation and reduced ischemia time. CONCLUSIONS: Adequate execution and perfect knowledge of the technique for surgical removal and anatomy reduces the rate of graft losses associated to inadequate harvesting techniques.


Assuntos
Transplante de Rim , Obtenção de Tecidos e Órgãos , Humanos , Sobrevivência de Enxerto , Rim/cirurgia , Doadores de Tecidos
4.
Med Intensiva ; 36(9): 611-8, 2012 Dec.
Artigo em Espanhol | MEDLINE | ID: mdl-22425337

RESUMO

PURPOSE: To examine the predictive value of an early transcranial Doppler ultrasound (TCD) study performed in the emergency department in patients with spontaneous subarachoniod hemorrhage (SAH) in good neurological condition, in order to know which patients are at high risk of developing delayed cerebral ischemia (DCI). DESIGN: A descriptive observational study was carried out involving a period of 3 years. SETTING: Critical Care and Emergency Department. PATIENTS: The study consecutively included patients with SAH of grade I-III on the Hunt and Hess scale. VARIABLES OF INTEREST: DCI (decrease of 2 points in GCS or focal deficit), Mean Velocity (MV) of middle cerebral arteries (MCA), Lindegaard Index (IL). Sonographic vasospasm pattern (SVP) was considered if MCA-MV>120cm/sc and IL>3. RESULTS: The mean age of the 122 patients was 54.1±13.7 years; 57.3% were women. SVP was detected in 24 patients (19.7%), although high velocities patterns (HVP) were present in 38 patients (31.1%). DCI developed in 21 patients (MV183+/-49cm/sc), all with previous SVP. In this group MV increased 22+/-5cm/sc/day during the first 3 days. The group without HVP (84 patients/MV of 67+/-16.6cm/sc), compared with DCI group, showed differences in highest MV (p<0.001), and also ΔMV/day (8.30+/-4,5cm/sc Vs 22+/-5cm/sc) during the first 3 days (p=0.009). In our series, ROC analysis selected the best cut-off value for ΔMV/day as 21cm/sc (p<0.001). CONCLUSION: During the first 3 days, an increase of 21cm/s/24h in MCA-MV was associated with the development of symptomatic vasospasm. TCD is a useful tool for the early detection of patients at risk of DCI after SAH.


Assuntos
Hemorragia Subaracnóidea/complicações , Hemorragia Subaracnóidea/diagnóstico por imagem , Ultrassonografia Doppler Transcraniana , Vasoespasmo Intracraniano/etiologia , Emergências , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes
5.
Sci Total Environ ; 766: 144393, 2021 Apr 20.
Artigo em Inglês | MEDLINE | ID: mdl-33418266

RESUMO

Health risks due to NO2 exposure commonly exceed acceptable levels in modern societies. Among the measures to reduce such risks, photocatalytic materials present a promising technology. However, while the pollutant remediation of such materials has been extensively validated in laboratory studies, the performance under real world environmental exposure conditions is still subject to controversy. Indeed, a comparison of available in-situ monitoring studies manifests non-conclusive and highly scattered results regarding the photocatalytic effectiveness observed. The reasons for this behaviour must be carefully explored in order to prevent non-efficient photocatalytic applications from being put into practice on a larger scale. This paper presents a comprehensive large-scale study for assessing the photocatalytic NO2 remediation by active pavements in a street of Madrid (Spain), comprising different in-situ monitoring techniques. The discussion is enriched by relating the obtained results to those of other large-scale studies. The discrepancies between these results may be traced back to different circumstances, among them the distance between the active pavement and the pollutant concentration sampling inlet, as well as to significant site-specific and time-dependent variations of pollutant concentrations and climatic parameters. Under due consideration of these influences, for materials with relatively high initial effectiveness, it was concluded that in most such applications, the average NO2 removal effectiveness, if evaluated at a typical inlet height of Air Quality Stations (3 m), will not exceed a value of 4% (averaged over a sufficiently large number of measurement points in the area of application and a sustained amount of time, i.e. several months). When considering more realistic human exposure conditions (lower heights and daytime), it might be justified to assume somewhat higher average effectiveness.

6.
Sci Total Environ ; 719: 137459, 2020 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-32151396

RESUMO

Photocatalytic technology implemented in construction materials is a promising solution to contribute to alleviate air quality issues found in big cities. Photocatalysis has been proved able to mineralise most harmful contaminants. However, important problems associated with monitoring the efficiency of these solutions under real conditions still remain, including the lack of affordable analytical tools to measure NOx concentrations with enough accuracy. In this work, two pilot scale demonstration platforms were built at two different locations to assess the photocatalytic NOX removal efficiency of ten selected materials exposed outdoors for AQmesh low-cost sensor PODs were used to measure ground-level to measure NO and NO2 concentrations during nearly one year. The pollutant removal efficiency of the materials was then calculated based on a comparison with simultaneously concentration measurements carried-out on reference, non-active materials. It was found that the NO2 removal efficiency presented large variations across the seasons, with maxima during the warmer months, while NO efficiencies were comparatively steadier. Statistical analysis delivered evidence that the efficiencies significantly depend on different meteorological variables (irradiance and relative humidity) besides NO, NO2 ambient concentrations. Lower efficiencies were observed for higher concentration levels and vice versa. The influence of water vapour could be related to two different effects: a short-term contribution by the instantaneous air humidity and a long-term component associated with the hygroscopic state of the material. The contribution of wind to the pollutant removal efficiencies was principally related to the humidity of air masses moving above the location and to the advection of pollutants from specific emission sources.

8.
Actas Urol Esp ; 30(7): 675-83, 2006.
Artigo em Espanhol | MEDLINE | ID: mdl-17058612

RESUMO

INTRODUCTION AND OBJECTIVES: The improvements in the management of newborns with myelomeningocele (MMC) have obtained a big increase in survival, allowing them to get longevity like never before, but data regarding urologic diseases during adult age are still missing. We herein evaluate the features of urinary lithiasis in adults born with MMC and the therapies used for its treatment. MATERIAL AND METHOD: We review 52 patients diagnosed at birth of MMC, between 18 and 40 years old, treated in our institution, with a mean follow-up of 6.7 years. RESULTS: 10 patients (19.2%) were diagnosed of urolithiasis. Three developed kidney calculi and one of them, with 7 more patients, developed bladder calculi (15.3%). The neurological level was < or = L2 in 3 cases, L2-S1 in 5, and > or = S1 in the other two. The type of neurogenic dysfunction of inferior urinary tract was multiple lesion of lower motor neurone in 6 cases, upper motor neurone in 1 case, multiple mixed lesion in 1 case and in case it was impossible to determine. Two patients had a bladder augmentation procedure and one of these with other 3 patients had a non-functional AMS-800 artificial urinary sphincter. Bladder stones were treated endoscopically in 14 procedures and by suprapubic cystolithotomy in 4 procedures, combined with removal of AMS-800 in 3 of them. One patient spontaneously passed a small stone. In one case, 2 ESWL and 2 percutaneous nephrolithotomies were needed. Three patients developed multiple recurrences during follow-up. CONCLUSIONS: Urinary lithiasis is common in adults with MMC. Some distinct features of these patients, together with their anatomical configuration and some therapies used in them, cause diagnostic, therapeutic and prophylaxis issues for the calculi they may develop.


Assuntos
Cálculos Renais/etiologia , Meningomielocele/complicações , Cálculos da Bexiga Urinária/etiologia , Adolescente , Adulto , Feminino , Humanos , Masculino
9.
Transplant Proc ; 37(5): 1990-2, 2005 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-15964320

RESUMO

Secondary brain insults predominantly due to hypotension are frequent among patients with fatal traumatic brain injury. We assessed the correlation between different systemic secondary brain insults and brain death in 404 patients admitted to our intensive care unit (ICU) after severe traumatic brain injury. We collated data on hypoxemia and hypotension prior to as well as the occurrence of hypoxemia, hypotension, shock, anemia, hyperglycemia, and hyperthermia within the first 24 hours after ICU admission. We also considered both the presence of extracranial injuries and the category of traumatic brain injury using computerized tomography. The 59 patients (14.6%) who developed brain death, were significantly older than patients without a fatal neurological outcome (46.1 +/- 22 vs 29.5 +/- 14.9 years; P < .0001). Intracranial mass lesions, whether surgically evacuated were more frequent among brain-dead patients. The systemic secondary brain insults significantly associated with brain death were hypoxemia, hypotension, shock, anemia, and hyperglycemia within the first 24 hours after ICU admission. After multivariate analysis, the factors that independently predicted brain death were the occurrence of shock (odds ratio [OR], 6.74; 95% confidence interval [CI], 2.85-15.84; P = .001) and older age (OR, 1.05; 95% CI, 1.03-1.07; P = .003). In conclusion, early shock seems to be the major systemic secondary brain insult associated with brain death in patients with severe traumatic brain injury. Prevention of or correction of shock might help to either decrease the occurrence of a fatal neurological outcome or in brain-dead patients to preserve organs in better condition for procurement.


Assuntos
Morte Encefálica/fisiopatologia , Lesões Encefálicas/fisiopatologia , Adulto , Encéfalo/patologia , Encéfalo/cirurgia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada
10.
Neurocirugia (Astur) ; 16(4): 323-32, 2005 Aug.
Artigo em Espanhol | MEDLINE | ID: mdl-16143806

RESUMO

OBJECTIVES: To determine the correlation between blood lactic acid levels in the first 48 hours and outcome, in hemodynamically stable patients, with moderate or severe head injury (HI), and to investigate the risk factors associated with abnormal lactate levels. MATERIAL AND METHODS: A prospective observational study, in 210 adults patients with moderate or severe head injury. When the patients were hemodynamically stable, blood lactate concentrations were measured once on admission, twice daily during the first 2 days and once daily until lactate levels were normalized. The whole group 210 patients were divided into 2 groups. Group 1: (LA < 2.2 mmol/L) patients without occult hypoperfussion (OH), and group 2: (LA >or= 2.2 mmol/L) patients with OH. RESULTS: One hundred and fifteen patients (57.76%) were categorized as group 1, and 95 patients (45.24%) as group 2. In the univariate analysis of risk factors for blood lactate >or=2.2 mmol/L the following variables showed statistical significance: severity of the head injury measured by several scales [Glasgow Coma Scale (GCS), Injury Severity Score (ISS), Revised Trauma Score (RTS) and Acute Physiology and Chronic Health Evaluation (APACHE) II], arterial hypotension, hypoxemia, anaemia, hyperglucemia, hypothermia, a greater incidence of norepinephrine infusion, and the higher percentage of type II lesions in the head computerized tomography at admission showed in the group 1 (53.91% vs. 38.94%) (p<0.03). In the multiple logistic regression analysis only two variables were risk independently associated with elevated blood lactate concentration: APACHE II in the first 24 hours: OR 1.12 (95% IC 1.06--1.196; p<0.0001) and the first 48-hours total fluid infusion volumes: OR 1.09 (95% IC 1.021,16; p < 0.0001). The infection rate (63.2% vs 47.8%, p=0.026), and length of ICU stay [mediana (percentil 25--75)] [13.29 (7.11--21.22) days vs. 8.78 (4.40--16.72) days; p<0.018] were significantly higher in patients with blood lactate >or=2.2 mmol/L (group 2). Although, the percentage of intracranial hypertension and mortality was higher in the group 2, there was no significant difference. In the multivariate analysis, the increase of blood lactate concentration, was not independently associated as a risk factor with studied complications. CONCLUSIONS: The presence of OH in patients with moderate or severe head injury, with postres uscitation arterial pressure, according to present recommendations, is associated with a more severe head injury, showed by APACHE II and the total fluid infusion volumes in the first 48 hours. OH in head injury increases the infection rate and length of ICU stay.


Assuntos
Lesões Encefálicas/fisiopatologia , Encéfalo/irrigação sanguínea , Adolescente , Adulto , Idoso , Encéfalo/metabolismo , Circulação Cerebrovascular/fisiologia , Estudos de Coortes , Feminino , Escala de Coma de Glasgow , Humanos , Masculino , Pessoa de Meia-Idade , Oxigênio/metabolismo , Estudos Prospectivos , Fatores de Risco
11.
Actas Urol Esp ; 29(5): 523-5, 2005 May.
Artigo em Espanhol | MEDLINE | ID: mdl-16013801

RESUMO

A 38 years old man with the only past medical history of bilateral orchiopexy 15 years ago is diagnosed of left primary seminal vesicle abscess. The patient is sent to our emergency service with an ultrasound finding of either dilated vas deferent or seminal vesicle abscess with hiperecogenic material inside it. The examination was performed after a 5 month history of purulent ejaculation. The diagnose of seminal vesicle abscess is confirmed by TRUS and, in the same procedure, drainage of the abscess was completed by needle-aspiration puncture. After this treatment the patient stay 12 hours at the observation room with intravenous antibiotics and is discharged home with oral antibiotics. We are interested in this case because of the low incidence of this pathology and the easy diagnosis and treatment by TRUS.


Assuntos
Abscesso/diagnóstico por imagem , Doenças dos Genitais Masculinos/diagnóstico por imagem , Glândulas Seminais/diagnóstico por imagem , Ultrassonografia/métodos , Abscesso/tratamento farmacológico , Abscesso/microbiologia , Adulto , Escherichia coli/isolamento & purificação , Infecções por Escherichia coli/complicações , Infecções por Escherichia coli/diagnóstico por imagem , Infecções por Escherichia coli/tratamento farmacológico , Doenças dos Genitais Masculinos/tratamento farmacológico , Doenças dos Genitais Masculinos/microbiologia , Humanos , Masculino , Glândulas Seminais/microbiologia , Resultado do Tratamento
13.
Diabetes Res Clin Pract ; 52(1): 1-9, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11182211

RESUMO

Helicobacter pylori (Hp) infection plays a role in gastric emptying (GE) in type 1 diabetic patients and may have implications for glycaemic control. The aim of our study was to investigate this relationship. Gastric emptying was studied in 13 patients with type 1 diabetes and Hp infection. The Hp infection status was assessed by serology and urease breath test (UBT). In addition upper gastrointestinal endoscopy with gastric mucosal biopsy was performed to look for gastritis. A radionuclide-labeled solid meal was used to study GE before and after eradication therapy (amoxicillin, clarithromycin and omeprazole) for Hp infection. All patients were evaluated for autonomic and peripheral neuropathy and were asked for symptoms of gastrointestinal motor dysfunction. Blood glucose levels were determined before the meal and at 30,60,90 and 120 min after the start of the meal. Home blood glucose self-monitoring and HbA(1c) were performed to document glycaemic control during the study. Three months after treatment, five patients were free of Hp infection and were without gastritis (group I: no Hp infection, no gastritis); eight of the patients continued to have gastritis after treatment (group II) and of these eight patients, six had gastritis without Hp infection and two had gastritis plus persistent Hp infection. These last two patients were re-treated with eradication therapy. Patients with gastritis were re-evaluated 6 months after initial treatment; at which time four were now free of gastritis and were added to group I (n=9) while four continual to have gastritis although without Hp infection (group II, n=4). In group I, GE half-time showed an increase (30.6+/-10.3 min vs. 60.2+/-15.4 min; P<0.05) while no change (28.8+/-9.5 vs. 26.9+/-8.7 min; n.s.) was observed in group II. GE half-time was not altered by autonomic and peripheral neuropathy or blood glucose during solid meal test. HbA(1c) did not change significantly after treatment in either groups but the blood glucose levels were more stable in group I compared to group II. A delay in GE was observed with disappearance of gastritis associated to H. pylori infection after eradication treatment in patients with type 1 diabetes. This change in GE could help to stabilise the blood glucose levels in these patients treated with insulin before each meal.


Assuntos
Glicemia/metabolismo , Diabetes Mellitus Tipo 1/fisiopatologia , Neuropatias Diabéticas/fisiopatologia , Esvaziamento Gástrico , Infecções por Helicobacter/fisiopatologia , Helicobacter pylori , Adulto , Idoso , Amoxicilina/uso terapêutico , Anticorpos Antibacterianos/sangue , Claritromicina/uso terapêutico , Diabetes Mellitus Tipo 1/complicações , Diabetes Mellitus Tipo 1/tratamento farmacológico , Neuropatias Diabéticas/diagnóstico , Quimioterapia Combinada/uso terapêutico , Feminino , Gastrite/microbiologia , Gastrite/fisiopatologia , Hemoglobinas Glicadas/análise , Infecções por Helicobacter/complicações , Infecções por Helicobacter/diagnóstico , Infecções por Helicobacter/tratamento farmacológico , Humanos , Imunoglobulina G/sangue , Masculino , Pessoa de Meia-Idade , Exame Neurológico , Omeprazol/uso terapêutico
14.
Transplant Proc ; 35(5): 1661-3, 2003 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-12962747

RESUMO

OBJECTIVES: To evaluate hydrodynamic, biochemical, and histological consequences of hypothermic isolated renal perfusion using a new computerized perfusion system. MATERIALS AND METHODS: The device that allowed us to obtain on renal hydrodynamics during perfusion included multiple parts. The organ was perfused at 4 degrees C with a constant flow either using a classic roller pump or a pump designed in our laboratory to employ vacuum or atmospheric pressure sequentially to achieve a truly pulsatile wave (vacuum-powered tubular pump). The study included 16 minipigs with Eurocollins or Belzer perfusion solutions sampled at predefined interval and histological studies of the organs performed. RESULTS: There was a significant difference in weight increase between the two types of pumps; those perfused with Eurocollins showed greater values than those with Belzer solution. Onset of nitric oxide (NO) in the perfusion solution increased inversely with the renal vascular resistance. The highest NO levels were observed with the Belzer solution and vacuum pump. CONCLUSIONS: Changes in renal hydrodynamics, as induced by perfusion wave form and solution type, may be recorded in real time using a computerized system. A vacuum pump with the Belzer solution achieved the best experimental results.


Assuntos
Rim/fisiologia , Urodinâmica/fisiologia , Animais , Rim/irrigação sanguínea , Modelos Animais , Preservação de Órgãos/instrumentação , Preservação de Órgãos/métodos , Perfusão/instrumentação , Perfusão/métodos , Pressão , Circulação Renal/fisiologia , Suínos , Porco Miniatura
15.
Rev Neurol ; 38(5): 411-6, 2004.
Artigo em Espanhol | MEDLINE | ID: mdl-15029516

RESUMO

INTRODUCTION: Transcranial Doppler (TCD) constitutes a valuable method for managing acute/critical neurological patients and it would therefore be interesting to reduce, as far as possible, the complexity involved in interpreting its findings. AIMS: The Objective of this study was to design and validate a correlation diagram of the echographic patterns and acute haemodynamic situations in the brain that makes it easier to teach and optimises the effectiveness of TCD as a diagnostic aid. MATERIALS AND METHODS: A diagram that represents the average speed and pulsatility index on a system of coordinates. Five fundamental echographic patterns were identified and the most frequent acute cerebral haemodynamic situations are detailed for each of them. The value of the diagram was tested in resident doctors with varying degrees of knowledge of TCD. In the first phase with no diagram (evaluation A), the interpretation of the TCD and diagnosis of the haemodynamic situation in the brain were evaluated in nine clinical cases. In the second phase, with a diagram (evaluation B), they were asked to draw up new reports on the same cases. We compared the number of times they were right in the two evaluations. RESULTS: A total of 216 echographic reports were obtained. The mean number of correct answers in evaluation A was 2, interquartile range (0.25 3.75). In evaluation B the number of correct answers rose to 4 (3.25 6.75) (p= 0.005). Using the diagram increased the diagnostic capacity of all the residents, but especially so in those with less training. CONCLUSIONS: Use of the diagram makes it easier for people who are not experts to learn to interpret TCD findings in acute/critical neurological situations.


Assuntos
Circulação Cerebrovascular , Transtornos Cerebrovasculares/diagnóstico por imagem , Materiais de Ensino , Ultrassonografia Doppler Transcraniana , Cuidados Críticos , Educação de Pós-Graduação em Medicina , Humanos , Internato e Residência , Aprendizagem , Prontuários Médicos , Médicos/psicologia
16.
Neurocirugia (Astur) ; 14(4): 295-300; discussion 300-1, 2003 Sep.
Artigo em Espanhol | MEDLINE | ID: mdl-14506552

RESUMO

OBJECTIVE: To ascertain the value of transcranial Doppler ultrasonography (TCD) in the first 24 hours of hospital admission in patients suffering good-grade spontaneous subarachnoid hemorrhage (SAH) in order to detect a high-risk group for symptomatic vasospasm. METHOD: Forty-nine spontaneous good-grade SAH were included. The first TCD studies were carried out at the Emergency Department. At least one more TCD recording was performed between the 4th and 14th day. Patients were classified according to whether they came to the hospital during the first 72 hours after the haemorrhage (Group 1) or later (Group 2). FINDINGS: Thirty three patients were included in Group 1 and sixteen patients in Group 2. Thirteen patients (26.5%) had sonographic vasospasm. In eight of these patients (61 %), the vasospasm was symptomatic. The initial mean velocity (MV) for Group 1 was normal. The increase in MV/24h (MV/24h) within the first 72 hours after SAH was higher (p< 0.007), in those whose developed sonographic vasospasm. In Group 2, the initial MV was greater (p< 0.001)) in patients who suffered sonographic vasospasm, with or without symptoms. CONCLUSIONS: The ability of TCD recorded in the first 24 hours of hospital admission to detect high-risk vasospasm patients for SAH with low clinical severity helps decide the most efficient patient destination. During the first three days the MV/24h is of value but not the absolute figure of the MV. In contrast, between the 4th and 14th day after SAH, the absolute figure of MV was useful to predict vasospasm.


Assuntos
Serviços Médicos de Emergência , Hemorragia Subaracnóidea/diagnóstico por imagem , Hemorragia Subaracnóidea/etiologia , Ultrassonografia Doppler Transcraniana/métodos , Velocidade do Fluxo Sanguíneo , Encéfalo/irrigação sanguínea , Isquemia Encefálica/diagnóstico por imagem , Estudos de Coortes , Diagnóstico Diferencial , Ecoencefalografia/métodos , Humanos , Estudos Prospectivos , Índice de Gravidade de Doença , Vasoespasmo Intracraniano/diagnóstico por imagem
17.
Neurocirugia (Astur) ; 13(3): 196-208, 2002 Jun.
Artigo em Espanhol | MEDLINE | ID: mdl-12148164

RESUMO

OBJECTIVES: 1) To know the transcranial Doppler (TCD) patterns in the early phase of the severe and moderate head injury and its prognostic implications. 2) To ascertain the TCD measurements concordance among different operators. MATERIAL AND METHODS: A prospective observational study in 275 consecutive intensive care unit patients with severe or moderate head injury was designed. Within 12 hrs. of the traumatic event a TCD study was done and a second one within the first 24 hrs. All patients were managed following a protocol made with the aim of promoting the early evacuation of the intracranial space occupying mass, preventing delayed brain damage and keeping the intracranial pressure (ICP) < 20 mm Hg and the cerebral perfusion pressure (CPP) > 60 mm Hg. The patient outcome was categorized with the Glasgow Outcome Score (GOS) at the discharge of the ICU. The mean velocity (MV) and the pulsatily index (PI) were measured in both middle cerebral arteries (MCA) and in the intracranial part of the internal carotid arteries in order to calculate the Lindegaard index. The presence of hypoperfusion, hyperaemia, vasospasm and cerebral circulatory arrest was registered. The presence of high intracranial pressure (HICP), the ICP peak and mode, the lowest CPP, the CPP mode, the minor medium arterial pressure (MAP) and the MAP mode were also recorded. A concordance analysis was made to ascertain the validity of the TCD data obtained by different operators. RESULTS: The concordance analysis among observers showed a kappa index of 0.7863 (p < 0.0001). The median stay in ICU was 7 days (Q1-Q3 of 3-15 days). The intra-ICU mortality was 20.72% (57/275) and the 53.44% of patients (147/275) showed favourable outcome (GOS 4-5) at the discharge of the ICU. The initial TCD showed a MV decreased and a PI increased in the MCA. Eighty of the e 275 patients showed a normal haemodynamic pattern whereas the pattern was abnormal in the remaining 195, degrees the hypoperfusion pattern predominated overall (181/275, 61.87%). HIPO was registered in 123 patients (58.01) an not in 89 (41.99%). A statistic significant correlation was found between the HICP and the DTC data. The early hypoperfusion pattern was related with a higher incidence of HICP (p > 0.05). The decrease in the MV and the increase in the PI were significantly associated with a higher mortality and a worse functional outcome (except for the MV within the first day). The PI was high within the first 24 h in the group of patients who died but was normalised among the survivals group. CONCLUSIONS: Early TCD detects a cerebral hypoperfusion status in the severe and moderate head injury that may imply therapeutic considerations. This hypoperfusion strongly correlates with the severity of the injury, the incidence of HICP and the functional outcome at the ICU discharge. In experienced hands, TCD measurements are reliable when done by different operators.


Assuntos
Traumatismos Craniocerebrais/diagnóstico por imagem , Ultrassonografia Doppler Transcraniana/métodos , Doença Aguda , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Encéfalo/irrigação sanguínea , Circulação Cerebrovascular/fisiologia , Criança , Pré-Escolar , Feminino , Escala de Coma de Glasgow , Humanos , Hipertensão Intracraniana/diagnóstico , Hipertensão Intracraniana/epidemiologia , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos
18.
Physiol Chem Phys Med NMR ; 27(3): 217-22, 1995.
Artigo em Inglês | MEDLINE | ID: mdl-8868581

RESUMO

This paper is related to periodic continuous responses of a new state derived from the interaction between low energies and matter. This effect was predicted by categoric developments and then verified by a photographic methodology. This experimental way is again used and once more it reveals new evidences on the structure of the irradiated matter and, consequently, on the mathematical properties of a Cartesian product operation used for the representations. Experiments with successive irradiations with visible light (lambda = 546.1 nm; I = 3350 lux) on a photographic developer (methyl-p-aminephenol sulfate) are reported.


Assuntos
Efeitos da Radiação , Luz , Modelos Teóricos , Fotografação
19.
Actas Urol Esp ; 14(6): 452-4, 1990.
Artigo em Espanhol | MEDLINE | ID: mdl-2080739

RESUMO

Ureteral triplicity is a rare abnormality of which there are less than a hundred cases reported up to date. The possible absence of clinical signs can explain why this malformation passes unnoticed specially when there are blind branches and dysplastic renal segments. The paper presents the case of a 43 year-old male, attending the clinic on a testicle tumour consultation, in which in spite of the previously mentioned circumstances a preoperative diagnosis of trifid ureter with ipsilateral ureterocele and renal dysplasia was reached owing to the use of C.A.T.


Assuntos
Anormalidades Múltiplas , Disgerminoma/complicações , Rim/anormalidades , Neoplasias Testiculares/complicações , Ureter/anormalidades , Ureter/diagnóstico por imagem , Ureterocele/complicações , Adulto , Humanos , Masculino , Tomografia Computadorizada por Raios X , Ureterocele/patologia
20.
Actas Urol Esp ; 16(3): 223-7, 1992 Mar.
Artigo em Espanhol | MEDLINE | ID: mdl-1621547

RESUMO

Surgical trauma of the pancreas cauda can occur when the renal hilum is dissected during left radical nephrectomy, mainly when normal anatomy is altered by the tumoral or inflammatory pathology. This lesion can be appreciated during the surgical procedure or else a pseudocyst or pancreatic fistula can become evident post-operatively. The urologist's knowledge of what the correct management both intra-operatively and postoperatively of this pathology should include will lessen the significant morbidity it implies. Presentation of a series of 6 patients presenting pancreatic trauma during left radical nephrectomy. Comments on the pathophysiology of this disorder, intra-operative management and post-operative treatment, specifically emphasizing the use of Total Parenteral Nutrition and Momatostatin IV.


Assuntos
Complicações Intraoperatórias/terapia , Nefrectomia , Pâncreas/lesões , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
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