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1.

Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Nimmerjahn, Falk; Vidarsson, Gestur; Cragg, Mark S.

Nat Immunol ; 24(8): 1244-1255, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37414906

2.

Publisher Correction: Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Nimmerjahn, Falk; Vidarsson, Gestur; Cragg, Mark S.

Nat Immunol ; 24(11): 1961, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37612468

3.

Publisher Correction: Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Nimmerjahn, Falk; Vidarsson, Gestur; Cragg, Mark S.

Nat Immunol ; 24(8): 1391, 2023 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-37438614

4.

Signaling through the Inhibitory Fc Receptor FcÎ³RIIB Induces CD8⁺ T Cell Apoptosis to Limit T Cell Immunity.

Morris, Anna B; Farley, Clara R; Pinelli, David F; Adams, Layne E; Cragg, Mark S; Boss, Jeremy M; Scharer, Christopher D; Fribourg, Miguel; Cravedi, Paolo; Heeger, Peter S; Ford, Mandy L.

Immunity ; 52(1): 136-150.e6, 2020 01 14.

Artigo em Inglês | MEDLINE | ID: mdl-31940267

5.

Reducing affinity as a strategy to boost immunomodulatory antibody agonism.

Yu, Xiaojie; Orr, Christian M; Chan, H T Claude; James, Sonya; Penfold, Christine A; Kim, Jinny; Inzhelevskaya, Tatyana; Mockridge, C Ian; Cox, Kerry L; Essex, Jonathan W; Tews, Ivo; Glennie, Martin J; Cragg, Mark S.

Nature ; 614(7948): 539-547, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36725933

6.

Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function.

Buchan, Sarah L; Dou, Lang; Remer, Marcus; Booth, Steven G; Dunn, Stuart N; Lai, Chester; Semmrich, Monika; Teige, Ingrid; Mårtensson, Linda; Penfold, Christine A; Chan, H T Claude; Willoughby, Jane E; Mockridge, C Ian; Dahal, Lekh N; Cleary, Kirstie L S; James, Sonya; Rogel, Anne; Kannisto, Päivi; Jernetz, Mats; Williams, Emily L; Healy, Eugene; Verbeek, J Sjef; Johnson, Peter W M; Frendéus, Björn; Cragg, Mark S; Glennie, Martin J; Gray, Juliet C; Al-Shamkhani, Aymen; Beers, Stephen A.

Immunity ; 49(5): 958-970.e7, 2018 11 20.

Artigo em Inglês | MEDLINE | ID: mdl-30446386

7.

Development of C1q Affinity Chromatography for the Study of C1q-IgG Interactions.

Marshall, Michael J E; Knaupp, Alexander; Spick, Christian; Koese, Ilker; Maier, Maria; Cragg, Mark S; Cymer, Florian; Schlothauer, Tilman.

J Immunol ; 210(11): 1837-1848, 2023 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-37093649

8.

Soluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity.

Kennedy, Paul T; Saulters, Emma L; Duckworth, Andrew D; Lim, Yeong Jer; Woolley, John F; Slupsky, Joseph R; Cragg, Mark S; Ward, Frank J; Dahal, Lekh N.

Mol Ther ; 32(2): 457-468, 2024 Feb 07.

Artigo em Inglês | MEDLINE | ID: mdl-38053333

9.

A single bout of vigorous intensity exercise enhances the efficacy of rituximab against human chronic lymphocytic leukaemia B-cells ex vivo.

Collier-Bain, Harrison D; Emery, Annabelle; Causer, Adam J; Brown, Frankie F; Oliver, Rebecca; Dutton, David; Crowe, Josephine; Augustine, Daniel; Graby, John; Leach, Shoji; Eddy, Rachel; Rothschild-Rodriguez, Daniela; Gray, Juliet C; Cragg, Mark S; Cleary, Kirstie L; Moore, Sally; Murray, James; Turner, James E; Campbell, John P.

Brain Behav Immun ; 118: 468-479, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38503395

10.

KIR2DS2 Expression Identifies NK Cells With Enhanced Anticancer Activity.

Blunt, Matthew D; Vallejo Pulido, Andres; Fisher, Jack G; Graham, Lara V; Doyle, Amber D P; Fulton, Rebecca; Carter, Matthew J; Polak, Marta; Johnson, Peter W M; Cragg, Mark S; Forconi, Francesco; Khakoo, Salim I.

J Immunol ; 209(2): 379-390, 2022 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-35768150

11.

Paradoxes of cancer: Survival at the brink.

Erenpreisa, Jekaterina; Salmina, Kristine; Anatskaya, Olga; Cragg, Mark S.

Semin Cancer Biol ; 81: 119-131, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-33340646

12.

Genetic dissection of a major haplotype associated with arthritis reveal FcÎ³R2b and FcÎ³R3 to act additively.

Vaartjes, Daniëlle; Klaczkowska, Dorota; Cragg, Mark S; Nandakumar, Kutty Selva; Bäckdahl, Liselotte; Holmdahl, Rikard.

Eur J Immunol ; 51(3): 682-693, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33244759

13.

Disparity in peripheral and renal B-cell depletion with rituximab in systemic lupus erythematosus: an opportunity for obinutuzumab?

Reddy, Venkat R; Pepper, Ruth J; Shah, Kavina; Cambridge, Geraldine; Henderson, Scott R; Klein, Christian; Kell, Loren; Taylor, Samuel J; Isenberg, David A; Cragg, Mark S; Leandro, Maria J.

Rheumatology (Oxford) ; 61(7): 2894-2904, 2022 07 06.

Artigo em Inglês | MEDLINE | ID: mdl-34788412

14.

Engineered antibodies to combat viral threats.

Yu, Xiaojie; Cragg, Mark S.

Nature ; 588(7838): 398-399, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-33208906

15.

VISTA deficiency protects from immune complex-mediated glomerulonephritis by inhibiting neutrophil activation.

Tham, El Li; Freeley, Simon J; Bearder, Siobhan; Barros, Fernanda Florez; Cragg, Mark S; Mócsai, Attila; Robson, Michael G.

J Autoimmun ; 113: 102501, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32586651

16.

Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcÎ³RIIB.

Stopforth, Richard J; Oldham, Robert J; Tutt, Alison L; Duriez, Patrick; Chan, H T Claude; Binkowski, Brock F; Zimprich, Chad; Li, Dun; Hargreaves, Philip G; Cong, Mei; Reddy, Venkat; Leandro, Maria J; Cambridge, Geraldine; Lux, Anja; Nimmerjahn, Falk; Cragg, Mark S.

J Immunol ; 200(5): 1937-1950, 2018 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-29351998

17.

The PI3KÎ´-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo.

Palazzo, Adam; Herter, Sylvia; Grosmaire, Laura; Jones, Randy; Frey, Christian R; Limani, Florian; Bacac, Marina; Umana, Pablo; Oldham, Robert J; Marshall, Michael J E; Cox, Kerry L; Turaj, Anna H; Cragg, Mark S; Klein, Christian; Carter, Matthew J; Tannheimer, Stacey.

J Immunol ; 200(7): 2304-2312, 2018 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-29453281

18.

Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation.

Johnston, Harvey E; Carter, Matthew J; Larrayoz, Marta; Clarke, James; Garbis, Spiro D; Oscier, David; Strefford, Jonathan C; Steele, Andrew J; Walewska, Renata; Cragg, Mark S.

Mol Cell Proteomics ; 17(4): 776-791, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29367434

19.

(SUMO)-wrestling with rituximab.

Cragg, Mark S.

Blood ; 139(18): 2728-2730, 2022 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-35511190

20.

Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms.

Cleary, Kirstie L S; Chan, H T Claude; James, Sonja; Glennie, Martin J; Cragg, Mark S.

J Immunol ; 198(10): 3999-4011, 2017 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-28404636

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Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Publisher Correction: Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Publisher Correction: Effect of posttranslational modifications and subclass on IgG activity: from immunity to immunotherapy.

Signaling through the Inhibitory Fc Receptor FcÎ³RIIB Induces CD8⁺ T Cell Apoptosis to Limit T Cell Immunity.

Reducing affinity as a strategy to boost immunomodulatory antibody agonism.

Antibodies to Costimulatory Receptor 4-1BB Enhance Anti-tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function.

Development of C1q Affinity Chromatography for the Study of C1q-IgG Interactions.

Soluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity.

A single bout of vigorous intensity exercise enhances the efficacy of rituximab against human chronic lymphocytic leukaemia B-cells ex vivo.

KIR2DS2 Expression Identifies NK Cells With Enhanced Anticancer Activity.

Paradoxes of cancer: Survival at the brink.

Genetic dissection of a major haplotype associated with arthritis reveal FcÎ³R2b and FcÎ³R3 to act additively.

Disparity in peripheral and renal B-cell depletion with rituximab in systemic lupus erythematosus: an opportunity for obinutuzumab?

Engineered antibodies to combat viral threats.

VISTA deficiency protects from immune complex-mediated glomerulonephritis by inhibiting neutrophil activation.

Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcÎ³RIIB.

The PI3KÎ´-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo.

Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation.

(SUMO)-wrestling with rituximab.

Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms.