Detalhe da pesquisa
1.
Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity.
Int J Obes (Lond)
; 40(6): 973-81, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26786350
2.
A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity.
Int J Obes (Lond)
; 39(2): 295-302, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24890885
3.
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene.
Nat Genet
; 16(3): 303-6, 1997 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-9207799
4.
Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice.
Proc Natl Acad Sci U S A
; 106(35): 14872-7, 2009 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19706465
5.
Deletion of C2orf34, PREPL and SLC3A1 causes atypical hypotonia-cystinuria syndrome.
J Med Genet
; 45(5): 314-8, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18234729
6.
Prenatal diagnosis of cerebral lesions in Tuberous sclerosis complex (TSC). Case report and review of the literature.
Eur J Paediatr Neurol
; 12(2): 123-6, 2008 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17681840
7.
[Alpha-foetoprotein assessment in amniotic fluid for the detection of neural tube defects: limited added value beyond week 20 ultrasound; retrospective study]. / Alfafoetoproteïnebepaling in vruchtwater voor de detectie van neuralebuisdefecten: beperkte meerwaarde boven de 20-wekenecho; retrospectiefonderzoek.
Ned Tijdschr Geneeskd
; 152(34): 1876-81, 2008 Aug 23.
Artigo
em Holandês
| MEDLINE | ID: mdl-18788679
8.
Human lactase-phlorizin hydrolase is not processed by furin, PC1/PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases.
Biochim Biophys Acta
; 1311(3): 199-203, 1996 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-8664347
9.
Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes.
Biochim Biophys Acta
; 1246(2): 185-8, 1995 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-7819286
10.
Expression in human lung tumor cells of the proprotein processing enzyme PC1/PC3. Cloning and primary sequence of a 5 kb cDNA.
FEBS Lett
; 300(1): 82-8, 1992 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-1547893
11.
Proprotein processing activity and cleavage site selectivity of the Kex2-like endoprotease PACE4.
FEBS Lett
; 336(1): 65-9, 1993 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-8262218
12.
Furin-mediated proprotein processing activity: involvement of negatively charged amino acid residues in the substrate binding region.
Biochimie
; 76(3-4): 210-6, 1994.
Artigo
em Inglês
| MEDLINE | ID: mdl-7819325
13.
The Dfur2 gene of Drosophila melanogaster: genetic organization, expression during embryogenesis, and pro-protein processing activity of its translational product Dfurin2.
DNA Cell Biol
; 14(3): 223-34, 1995 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-7880443
14.
Development and characterization of a panel of monoclonal antibodies against the novel subtilisin-like proprotein processing enzyme furin.
Hybridoma
; 11(1): 71-86, 1992 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-1737642
15.
Limitations of inhibitory activities of polyphenols on furin-mediated substrate processing.
Curr Med Chem
; 19(21): 3641-50, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22716122
16.
The autism candidate gene Neurobeachin encodes a scaffolding protein implicated in membrane trafficking and signaling.
Curr Mol Med
; 11(3): 204-17, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21375492
17.
Deletion of C2orf34, PREPL and SLC3A1 causes atypical hypotonia-cystinuria syndrome.
BMJ Case Rep
; 20092009.
Artigo
em Inglês
| MEDLINE | ID: mdl-21686663
18.
Molecular and cellular regulation of prohormone processing.
Semin Cell Dev Biol
; 9(1): 3-10, 1998 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-9572108
19.
Homology modelling of the catalytic domain of human furin. A model for the eukaryotic subtilisin-like proprotein convertases.
Eur J Biochem
; 222(2): 255-66, 1994 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-8020465
20.
Expression of the dibasic proprotein processing enzyme furin is directed by multiple promoters.
J Biol Chem
; 269(12): 9298-303, 1994 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-8132667