Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive.

Hovel-Miner, Galadriel; Mugnier, Monica R; Goldwater, Benjamin; Cross, George A M; Papavasiliou, F Nina.

PLoS Genet ; 12(5): e1005994, 2016 05.

Artigo em Inglês | MEDLINE | ID: mdl-27149665

2.

Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei.

Siegel, T Nicolai; Hekstra, Doeke R; Kemp, Louise E; Figueiredo, Luisa M; Lowell, Joanna E; Fenyo, David; Wang, Xuning; Dewell, Scott; Cross, George A M.

Genes Dev ; 23(9): 1063-76, 2009 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-19369410

3.

A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei.

Boothroyd, Catharine E; Dreesen, Oliver; Leonova, Tatyana; Ly, K Ina; Figueiredo, Luisa M; Cross, George A M; Papavasiliou, F Nina.

Nature ; 459(7244): 278-81, 2009 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-19369939

4.

Trypanosoma brucei Orc1 is essential for nuclear DNA replication and affects both VSG silencing and VSG switching.

Benmerzouga, Imaan; Concepción-Acevedo, Jeniffer; Kim, Hee-Sook; Vandoros, Anthula V; Cross, George A M; Klingbeil, Michele M; Li, Bibo.

Mol Microbiol ; 87(1): 196-210, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23216794

5.

The essential polysome-associated RNA-binding protein RBP42 targets mRNAs involved in Trypanosoma brucei energy metabolism.

Das, Anish; Morales, Rachel; Banday, Mahrukh; Garcia, Stacey; Hao, Li; Cross, George A M; Estevez, Antonio M; Bellofatto, Vivian.

RNA ; 18(11): 1968-83, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22966087

6.

Telomere length affects the frequency and mechanism of antigenic variation in Trypanosoma brucei.

Hovel-Miner, Galadriel A; Boothroyd, Catharine E; Mugnier, Monica; Dreesen, Oliver; Cross, George A M; Papavasiliou, F Nina.

PLoS Pathog ; 8(8): e1002900, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-22952449

7.

TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.

Kim, Hee-Sook; Cross, George A M.

PLoS Pathog ; 6(7): e1000992, 2010 Jul 08.

Artigo em Inglês | MEDLINE | ID: mdl-20628569

8.

Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites.

Siegel, Tim Nicolai; Hekstra, Doeke R; Wang, Xuning; Dewell, Scott; Cross, George A M.

Nucleic Acids Res ; 38(15): 4946-57, 2010 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-20385579

9.

Two thymidine hydroxylases differentially regulate the formation of glucosylated DNA at regions flanking polymerase II polycistronic transcription units throughout the genome of Trypanosoma brucei.

Cliffe, Laura J; Siegel, T Nicolai; Marshall, Marion; Cross, George A M; Sabatini, Robert.

Nucleic Acids Res ; 38(12): 3923-35, 2010 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-20215442

10.

Multifunctional class I transcription in Trypanosoma brucei depends on a novel protein complex.

Brandenburg, Jens; Schimanski, Bernd; Nogoceke, Everson; Nguyen, Tu N; Padovan, Júlio C; Chait, Brian T; Cross, George A M; Günzl, Arthur.

EMBO J ; 26(23): 4856-66, 2007 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-17972917

11.

A histone methyltransferase modulates antigenic variation in African trypanosomes.

Figueiredo, Luisa M; Janzen, Christian J; Cross, George A M.

PLoS Biol ; 6(7): e161, 2008 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-18597556

12.

Drug discovery: Fat-free proteins kill parasites.

Cross, George A M.

Nature ; 464(7289): 689-90, 2010 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-20360728

13.

Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes.

Figueiredo, Luisa M; Cross, George A M.

Eukaryot Cell ; 9(1): 148-54, 2010 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-19915072

14.

Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes.

Kawahara, Taemi; Siegel, T Nicolai; Ingram, Alexandra K; Alsford, Sam; Cross, George A M; Horn, David.

Mol Microbiol ; 69(4): 1054-68, 2008 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-18631159

15.

Telomerase-independent stabilization of short telomeres in Trypanosoma brucei.

Dreesen, Oliver; Cross, George A M.

Mol Cell Biol ; 26(13): 4911-9, 2006 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-16782879

16.

Trypanosome H2Bv replaces H2B in nucleosomes enriched for H3 K4 and K76 trimethylation.

Mandava, Veena; Janzen, Christian J; Cross, George A M.

Biochem Biophys Res Commun ; 368(4): 846-51, 2008 Apr 18.

Artigo em Inglês | MEDLINE | ID: mdl-18261990

17.

Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging.

Siegel, T Nicolai; Hekstra, Doeke R; Cross, George A M.

Mol Biochem Parasitol ; 160(2): 171-4, 2008 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-18501977

18.

CRE recombinase-based positive-negative selection systems for genetic manipulation in Trypanosoma brucei.

Scahill, Michael D; Pastar, Irena; Cross, George A M.

Mol Biochem Parasitol ; 157(1): 73-82, 2008 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-18006158

19.

Trypanosome telomeres are protected by a homologue of mammalian TRF2.

Li, Bibo; Espinal, Amin; Cross, George A M.

Mol Cell Biol ; 25(12): 5011-21, 2005 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-15923618

20.

Systematic study of sequence motifs for RNA trans splicing in Trypanosoma brucei.

Siegel, T Nicolai; Tan, Kevin S W; Cross, George A M.

Mol Cell Biol ; 25(21): 9586-94, 2005 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-16227607

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