Detalhe da pesquisa
1.
Mathematical Modelling of Alternative Pathway of Complement System.
Bull Math Biol
; 82(2): 33, 2020 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32062771
2.
Interconvertible geometric isomers of Plasmodium falciparum dihydroorotate dehydrogenase inhibitors exhibit multiple binding modes.
Bioorg Med Chem Lett
; 27(16): 3878-3882, 2017 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28669445
3.
Correction to: Mathematical Modelling of Alternative Pathway of Complement System.
Bull Math Biol
; 84(1): 18, 2021 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34923606
4.
Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen.
Antimicrob Agents Chemother
; 59(2): 753-62, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25385118
5.
Pantothenic acid biosynthesis in the parasite Toxoplasma gondii: a target for chemotherapy.
Antimicrob Agents Chemother
; 58(11): 6345-53, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25049241
6.
An in silico structure-based approach to anti-infective drug discovery.
Parasitology
; 141(1): 17-27, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23768800
7.
Correction: Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
PLoS One
; 19(4): e0302418, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38626090
8.
Mathematical Modeling of Complement Pathway Dynamics for Target Validation and Selection of Drug Modalities for Complement Therapies.
Front Pharmacol
; 13: 855743, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35517827
9.
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity.
Structure
; 30(8): 1050-1054.e2, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35609600
10.
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies.
PLoS One
; 16(7): e0253364, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34270554
11.
Optimization of Hydantoins as Potent Antimycobacterial Decaprenylphosphoryl-ß-d-Ribose Oxidase (DprE1) Inhibitors.
J Med Chem
; 63(10): 5367-5386, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32342688
12.
Exploring the SAR of the ß-Ketoacyl-ACP Synthase Inhibitor GSK3011724A and Optimization around a Genotoxic Metabolite.
ACS Infect Dis
; 6(5): 1098-1109, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32196311
13.
Identification and Profiling of Hydantoins-A Novel Class of Potent Antimycobacterial DprE1 Inhibitors.
J Med Chem
; 61(24): 11221-11249, 2018 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30500189
14.
Differential characterization using readily accessible NMR experiments of novel N- and O-alkylated quinolin-4-ol, 1,5-naphthyridin-4-ol and quinazolin-4-ol derivatives with antimycobacterial activity.
Eur J Med Chem
; 125: 890-901, 2017 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27769030
15.
Design, synthesis and structure-activity relationship study of wollamide B; a new potential anti TB agent.
PLoS One
; 12(4): e0176088, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28423019
16.
Repurposing clinically approved cephalosporins for tuberculosis therapy.
Sci Rep
; 6: 34293, 2016 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27678056
17.
Searching for New Leads for Tuberculosis: Design, Synthesis, and Biological Evaluation of Novel 2-Quinolin-4-yloxyacetamides.
J Med Chem
; 59(14): 6709-28, 2016 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27348630
18.
Factors influencing the specificity of inhibitor binding to the human and malaria parasite dihydroorotate dehydrogenases.
J Med Chem
; 55(12): 5841-50, 2012 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22621375