Detalhe da pesquisa
1.
Preliminary preclinical study of Chol-DsiRNA polyplexes formed with PLL[30]-PEG[5K] for the RNAi-based therapy of breast cancer.
Nanomedicine
; 33: 102363, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33545405
2.
Encapsulation of an EP67-Conjugated CTL Peptide Vaccine in Nanoscale Biodegradable Particles Increases the Efficacy of Respiratory Immunization and Affects the Magnitude and Memory Subsets of Vaccine-Generated Mucosal and Systemic CD8+ T Cells in a Diameter-Dependent Manner.
Mol Pharm
; 14(5): 1469-1481, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28319404
3.
Peripherally cross-linking the shell of core-shell polymer micelles decreases premature release of physically loaded combretastatin A4 in whole blood and increases its mean residence time and subsequent potency against primary murine breast tumors after IV administration.
Pharm Res
; 32(3): 1028-44, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25223962
4.
Direct Comparison of Chol-siRNA Polyplexes and Chol-DsiRNA Polyplexes Targeting STAT3 in a Syngeneic Murine Model of TNBC.
Noncoding RNA
; 8(1)2022 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35076584
5.
Surface Modification of Biodegradable Microparticles with the Novel Host-Derived Immunostimulant CPDI-02 Significantly Increases Short-Term and Long-Term Mucosal and Systemic Antibodies against Encapsulated Protein Antigen in Young Naïve Mice after Respiratory Immunization.
Pharmaceutics
; 14(9)2022 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36145590
6.
Targeted Amino Acid Substitution Overcomes Scale-Up Challenges with the Human C5a-Derived Decapeptide Immunostimulant EP67.
ACS Infect Dis
; 6(5): 1169-1181, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32233506
7.
Surface conjugation of EP67 to biodegradable nanoparticles increases the generation of long-lived mucosal and systemic memory T-cells by encapsulated protein vaccine after respiratory immunization and subsequent T-cell-mediated protection against respiratory infection.
Int J Pharm
; 565: 242-257, 2019 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31077762
8.
Complexation of Chol-DsiRNA in place of Chol-siRNA greatly increases the duration of mRNA suppression by polyplexes of PLL(30)-PEG(5K) in primary murine syngeneic breast tumors after i.v. administration.
Int J Pharm
; 543(1-2): 130-138, 2018 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29601972