Detalhe da pesquisa
1.
Relationships between Inhibition, Transport and Enhanced Transport via the Organic Cation Transporter 1.
Int J Mol Sci
; 23(4)2022 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35216120
2.
Substrates of the Human Brain Proton-Organic Cation Antiporter and Comparison with Organic Cation Transporter 1 Activities.
Int J Mol Sci
; 23(15)2022 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35955563
3.
Overlap and Specificity in the Substrate Spectra of Human Monoamine Transporters and Organic Cation Transporters 1, 2, and 3.
Int J Mol Sci
; 22(23)2021 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34884618
4.
Targeted mutagenesis of negatively charged amino acids outlining the substrate translocation path within the human organic cation transporter 3.
Biochem Pharmacol
; 223: 116188, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38580166
5.
Combined and independent effects of OCT1 and CYP2D6 on the cellular disposition of drugs.
Biomed Pharmacother
; 161: 114454, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36871537
6.
Substrates and Inhibitors of the Organic Cation Transporter 3 and Comparison with OCT1 and OCT2.
J Med Chem
; 65(18): 12403-12416, 2022 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36067397
7.
The mystery of the human proton-organic cation antiporter: One transport protein or many?
Pharmacol Ther
; 239: 108283, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36162727
8.
How precise is quantitative prediction of pharmacokinetic effects due to drug-drug interactions and genotype from in vitro data? A comprehensive analysis on the example CYP2D6 and CYP2C19 substrates.
Pharmacol Ther
; 217: 107629, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32682785
9.
Identification of Novel High-Affinity Substrates of OCT1 Using Machine Learning-Guided Virtual Screening and Experimental Validation.
J Med Chem
; 64(5): 2762-2776, 2021 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33606526
10.
Excess Mortality in Aspirin and Dipyrone (Metamizole) Co-Medicated in Patients With Cardiovascular Disease: A Nationwide Study.
J Am Heart Assoc
; 10(22): e022299, 2021 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34726072
11.
Genomic Variation and Pharmacokinetics in Old Age: A Quantitative Review of Age- vs. Genotype-Related Differences.
Clin Pharmacol Ther
; 105(3): 625-640, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29498032