Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency.

Daou, Salima; Talukdar, Manisha; Tang, Jinle; Dong, Beihua; Banerjee, Shuvojit; Li, Yize; Duffy, Nicole M; Ogunjimi, Abiodun A; Gaughan, Christina; Jha, Babal K; Gish, Gerald; Tavernier, Nicolas; Mao, Daniel; Weiss, Susan R; Huang, Hao; Silverman, Robert H; Sicheri, Frank.

Proc Natl Acad Sci U S A ; 117(40): 24802-24812, 2020 10 06.

Artigo em Inglês | MEDLINE | ID: mdl-32958664

2.

A potent nuclear export mechanism imposes USP16 cytoplasmic localization during interphase.

Sen Nkwe, Nadine; Daou, Salima; Uriarte, Maxime; Gagnon, Jessica; Iannantuono, Nicholas Victor; Barbour, Haithem; Yu, Helen; Masclef, Louis; Fernández, Erlinda; Zamorano Cuervo, Natalia; Mashtalir, Nazar; Binan, Loïc; Sergeev, Mikhail; Bélanger, François; Drobetsky, Elliot; Milot, Eric; Wurtele, Hugo; Costantino, Santiago; Affar, El Bachir.

J Cell Sci ; 133(4)2020 02 24.

Artigo em Inglês | MEDLINE | ID: mdl-32005696

3.

Functional characterization of a PROTAC directed against BRAF mutant V600E.

Posternak, Ganna; Tang, Xiaojing; Maisonneuve, Pierre; Jin, Ting; Lavoie, Hugo; Daou, Salima; Orlicky, Stephen; Goullet de Rugy, Theo; Caldwell, Lauren; Chan, Kin; Aman, Ahmed; Prakesch, Michael; Poda, Gennady; Mader, Pavel; Wong, Cassandra; Maier, Stefan; Kitaygorodsky, Julia; Larsen, Brett; Colwill, Karen; Yin, Zhe; Ceccarelli, Derek F; Batey, Robert A; Taipale, Mikko; Kurinov, Igor; Uehling, David; Wrana, Jeff; Durocher, Daniel; Gingras, Anne-Claude; Al-Awar, Rima; Therrien, Marc; Sicheri, Frank.

Nat Chem Biol ; 16(11): 1170-1178, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32778845

4.

Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O.

Mashtalir, Nazar; Daou, Salima; Barbour, Haithem; Sen, Nadine N; Gagnon, Jessica; Hammond-Martel, Ian; Dar, Haider H; Therrien, Marc; Affar, El Bachir.

Mol Cell ; 54(3): 392-406, 2014 May 08.

Artigo em Inglês | MEDLINE | ID: mdl-24703950

5.

Vivid views of the PINK1 protein.

Daou, Salima; Sicheri, Frank.

Nature ; 552(7683): 38-39, 2017 12 07.

Artigo em Inglês | MEDLINE | ID: mdl-29219973

6.

The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.

Bottardi, Stefania; Mavoungou, Lionel; Pak, Helen; Daou, Salima; Bourgoin, Vincent; Lakehal, Yahia A; Affar, El Bachir; Milot, Eric.

PLoS Genet ; 10(12): e1004827, 2014 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-25474253

7.

Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair.

Yu, Helen; Pak, Helen; Hammond-Martel, Ian; Ghram, Mehdi; Rodrigue, Amélie; Daou, Salima; Barbour, Haithem; Corbeil, Luc; Hébert, Josée; Drobetsky, Elliot; Masson, Jean Yves; Di Noia, Javier M; Affar, El Bachir.

Proc Natl Acad Sci U S A ; 111(1): 285-90, 2014 Jan 07.

Artigo em Inglês | MEDLINE | ID: mdl-24347639

8.

The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.

Daou, Salima; Hammond-Martel, Ian; Mashtalir, Nazar; Barbour, Haithem; Gagnon, Jessica; Iannantuono, Nicholas V G; Nkwe, Nadine Sen; Motorina, Alena; Pak, Helen; Yu, Helen; Wurtele, Hugo; Milot, Eric; Mallette, Frédérick A; Carbone, Michele; Affar, El Bachir.

J Biol Chem ; 290(48): 28643-63, 2015 Nov 27.

Artigo em Inglês | MEDLINE | ID: mdl-26416890

9.

Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway.

Daou, Salima; Mashtalir, Nazar; Hammond-Martel, Ian; Pak, Helen; Yu, Helen; Sui, Guangchao; Vogel, Jodi L; Kristie, Thomas M; Affar, El Bachir.

Proc Natl Acad Sci U S A ; 108(7): 2747-52, 2011 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-21285374

10.

The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA.

Yin, Jay Z; Keszei, Alexander F A; Houliston, Scott; Filandr, Frantisek; Beenstock, Jonah; Daou, Salima; Kitaygorodsky, Julia; Schriemer, David C; Mazhab-Jafari, Mohammad T; Gingras, Anne-Claude; Sicheri, Frank.

Structure ; 2024 Mar 22.

Artigo em Inglês | MEDLINE | ID: mdl-38531363

11.

Electron transfer dissociation (ETD): the mass spectrometric breakthrough essential for O-GlcNAc protein site assignments-a study of the O-GlcNAcylated protein host cell factor C1.

Myers, Samuel A; Daou, Salima; Affar, El Bachir; Burlingame, Al.

Proteomics ; 13(6): 982-91, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23335398

12.

An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes.

Barbour, Haithem; Nkwe, Nadine Sen; Estavoyer, Benjamin; Messmer, Clémence; Gushul-Leclaire, Mila; Villot, Romain; Uriarte, Maxime; Boulay, Karine; Hlayhel, Sari; Farhat, Bassel; Milot, Eric; Mallette, Frédérick A; Daou, Salima; Affar, El Bachir.

iScience ; 26(5): 106276, 2023 May 19.

Artigo em Inglês | MEDLINE | ID: mdl-37168555

13.

Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis.

Uriarte, Maxime; Sen Nkwe, Nadine; Tremblay, Roch; Ahmed, Oumaima; Messmer, Clémence; Mashtalir, Nazar; Barbour, Haithem; Masclef, Louis; Voide, Marion; Viallard, Claire; Daou, Salima; Abdelhadi, Djaileb; Ronato, Daryl; Paydar, Mohammadjavad; Darracq, Anaïs; Boulay, Karine; Desjardins-Lecavalier, Nicolas; Sapieha, Przemyslaw; Masson, Jean-Yves; Sergeev, Mikhail; Kwok, Benjamin H; Hulea, Laura; Mallette, Frédérick A; Milot, Eric; Larrivée, Bruno; Wurtele, Hugo; Affar, El Bachir.

Nat Commun ; 12(1): 6984, 2021 11 30.

Artigo em Inglês | MEDLINE | ID: mdl-34848715

14.

Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes.

Barbour, Haithem; Daou, Salima; Hendzel, Michael; Affar, El Bachir.

Nat Commun ; 11(1): 5947, 2020 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-33230107

15.

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones.

Masclef, Louis; Maxime, Uriarte; Ahmed, Oumaima; Sen Nkwe, Nadine; Barbour, Haithem; Iannantuono, Nicholas V G; Boubekeur, Amina; Daou, Salima; Affar, El Bachir.

J Vis Exp ; (149)2019 07 25.

Artigo em Inglês | MEDLINE | ID: mdl-31403616

16.

Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1.

Daou, Salima; Barbour, Haithem; Ahmed, Oumaima; Masclef, Louis; Baril, Caroline; Sen Nkwe, Nadine; Tchelougou, Daméhan; Uriarte, Maxime; Bonneil, Eric; Ceccarelli, Derek; Mashtalir, Nazar; Tanji, Mika; Masson, Jean-Yves; Thibault, Pierre; Sicheri, Frank; Yang, Haining; Carbone, Michele; Therrien, Marc; Affar, El Bachir.

Nat Commun ; 9(1): 4385, 2018 10 22.

Artigo em Inglês | MEDLINE | ID: mdl-30349006

17.

Undetectable histone O-GlcNAcylation in mammalian cells.

Gagnon, Jessica; Daou, Salima; Zamorano, Natalia; Iannantuono, Nicholas V G; Hammond-Martel, Ian; Mashtalir, Nazar; Bonneil, Eric; Wurtele, Hugo; Thibault, Pierre; Affar, El Bachir.

Epigenetics ; 10(8): 677-91, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26075789

18.

The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.

Yu, Helen; Mashtalir, Nazar; Daou, Salima; Hammond-Martel, Ian; Ross, Julie; Sui, Guangchao; Hart, Gerald W; Rauscher, Frank J; Drobetsky, Elliot; Milot, Eric; Shi, Yang; Affar, El Bachir.

Mol Cell Biol ; 30(21): 5071-85, 2010 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-20805357

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