Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides.

Radakovic, Aleksandar; DasGupta, Saurja; Wright, Tom H; Aitken, Harry R M; Szostak, Jack W.

Proc Natl Acad Sci U S A ; 119(7)2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-35140183

2.

Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.

Krochmal, Daniel; Shao, Yaming; Li, Nan-Sheng; DasGupta, Saurja; Shelke, Sandip A; Koirala, Deepak; Piccirilli, Joseph A.

Nat Chem Biol ; 18(4): 376-384, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35058645

3.

REVERSE: a user-friendly web server for analyzing next-generation sequencing data from in vitro selection/evolution experiments.

Weiss, Zoe; DasGupta, Saurja.

Nucleic Acids Res ; 50(W1): W639-W650, 2022 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-35699225

4.

The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes.

DasGupta, Saurja; Nykiel, Kamila; Piccirilli, Joseph A.

RNA ; 27(9): 1017-1024, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34131025

5.

RNA-Catalyzed RNA Ligation within Prebiotically Plausible Model Protocells.

DasGupta, Saurja; Zhang, Stephanie J; Smela, Merrick P; Szostak, Jack W.

Chemistry ; 29(43): e202301376, 2023 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-37216492

6.

In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates.

Walton, Travis; DasGupta, Saurja; Duzdevich, Daniel; Oh, Seung Soo; Szostak, Jack W.

Proc Natl Acad Sci U S A ; 117(11): 5741-5748, 2020 03 17.

Artigo em Inglês | MEDLINE | ID: mdl-32123094

7.

The Varkud Satellite Ribozyme: A Thirty-Year Journey through Biochemistry, Crystallography, and Computation.

DasGupta, Saurja; Piccirilli, Joseph A.

Acc Chem Res ; 54(11): 2591-2602, 2021 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-33974386

8.

My lockdown literature-review challenge.

DasGupta, Saurja.

Nature ; 2021 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-33432213

9.

Frontiers in Prebiotic Chemistry and Early Earth Environments.

Müller, Ulrich F; Elsila, Jamie; Trail, Dustin; DasGupta, Saurja; Giese, Claudia-Corina; Walton, Craig R; Cohen, Zachary R; Stolar, Tomislav; Krishnamurthy, Ramanarayanan; Lyons, Timothy W; Rogers, Karyn L; Williams, Loren Dean.

Orig Life Evol Biosph ; 52(1-3): 165-181, 2022 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-35796897

10.

How memorable melodies can make your research sing.

DasGupta, Saurja.

Nature ; 2020 Nov 09.

Artigo em Inglês | MEDLINE | ID: mdl-33169028

11.

Molecular crowding and RNA catalysis.

DasGupta, Saurja.

Org Biomol Chem ; 18(39): 7724-7739, 2020 10 14.

Artigo em Inglês | MEDLINE | ID: mdl-32914154

12.

Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.

Koirala, Deepak; Shelke, Sandip A; Dupont, Marcel; Ruiz, Stormy; DasGupta, Saurja; Bailey, Lucas J; Benner, Steven A; Piccirilli, Joseph A.

Nucleic Acids Res ; 46(5): 2624-2635, 2018 03 16.

Artigo em Inglês | MEDLINE | ID: mdl-29309709

13.

Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen.

Biondi, Elisa; Lane, Joshua D; Das, Debasis; Dasgupta, Saurja; Piccirilli, Joseph A; Hoshika, Shuichi; Bradley, Kevin M; Krantz, Bryan A; Benner, Steven A.

Nucleic Acids Res ; 44(20): 9565-9577, 2016 Nov 16.

Artigo em Inglês | MEDLINE | ID: mdl-27701076

14.

Structural Basis for Substrate Helix Remodeling and Cleavage Loop Activation in the Varkud Satellite Ribozyme.

DasGupta, Saurja; Suslov, Nikolai B; Piccirilli, Joseph A.

J Am Chem Soc ; 139(28): 9591-9597, 2017 07 19.

Artigo em Inglês | MEDLINE | ID: mdl-28625058

15.

Crystal structure of the Varkud satellite ribozyme.

Suslov, Nikolai B; DasGupta, Saurja; Huang, Hao; Fuller, James R; Lilley, David M J; Rice, Phoebe A; Piccirilli, Joseph A.

Nat Chem Biol ; 11(11): 840-6, 2015 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-26414446

16.

Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life.

Cohen, Zachary R; Ding, Dian; Zhou, Lijun; DasGupta, Saurja; Haas, Sebastian; Sinclair, Kimberly P; Todd, Zoe R; Black, Roy A; Szostak, Jack W; Catling, David C.

PNAS Nexus ; 3(3): pgae084, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38505692

17.

Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly.

DasGupta, Saurja; Zhang, Stephanie; Szostak, Jack W.

ACS Cent Sci ; 9(8): 1670-1678, 2023 Aug 23.

Artigo em Inglês | MEDLINE | ID: mdl-37637737

18.

Hachimoji DNA and RNA: A genetic system with eight building blocks.

Hoshika, Shuichi; Leal, Nicole A; Kim, Myong-Jung; Kim, Myong-Sang; Karalkar, Nilesh B; Kim, Hyo-Joong; Bates, Alison M; Watkins, Norman E; SantaLucia, Holly A; Meyer, Adam J; DasGupta, Saurja; Piccirilli, Joseph A; Ellington, Andrew D; SantaLucia, John; Georgiadis, Millie M; Benner, Steven A.

Science ; 363(6429): 884-887, 2019 02 22.

Artigo em Inglês | MEDLINE | ID: mdl-30792304

19.

Spinach RNA aptamer detects lead(II) with high selectivity.

DasGupta, Saurja; Shelke, Sandip A; Li, Nan-sheng; Piccirilli, Joseph A.

Chem Commun (Camb) ; 51(43): 9034-7, 2015 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-25940073

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Nonenzymatic assembly of active chimeric ribozymes from aminoacylated RNA oligonucleotides.

Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.

REVERSE: a user-friendly web server for analyzing next-generation sequencing data from in vitro selection/evolution experiments.

The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes.

RNA-Catalyzed RNA Ligation within Prebiotically Plausible Model Protocells.

In vitro selection of ribozyme ligases that use prebiotically plausible 2-aminoimidazole-activated substrates.

The Varkud Satellite Ribozyme: A Thirty-Year Journey through Biochemistry, Crystallography, and Computation.

My lockdown literature-review challenge.

Frontiers in Prebiotic Chemistry and Early Earth Environments.

How memorable melodies can make your research sing.

Molecular crowding and RNA catalysis.

Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.

Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen.

Structural Basis for Substrate Helix Remodeling and Cleavage Loop Activation in the Varkud Satellite Ribozyme.

Crystal structure of the Varkud satellite ribozyme.

Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life.

Molecular Crowding Facilitates Ribozyme-Catalyzed RNA Assembly.

Hachimoji DNA and RNA: A genetic system with eight building blocks.

Spinach RNA aptamer detects lead(II) with high selectivity.