Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Improvement in Lung Clearance Index and Chest Computed Tomography Scores with Elexacaftor/Tezacaftor/Ivacaftor Treatment in People with Cystic Fibrosis Aged 12 Years and Older - The RECOVER Trial.

McNally, Paul; Lester, Karen; Stone, Gavin; Elnazir, Basil; Williamson, Michael; Cox, Des; Linnane, Barry; Kirwan, Laura; Rea, David; O'Regan, Paul; Semple, Tom; Saunders, Clare; Tiddens, Harm A W M; McKone, Edward; Davies, Jane C.

Am J Respir Crit Care Med ; 208(9): 917-929, 2023 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-37703083

2.

Long-Term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Children Aged â©¾6 Years with Cystic Fibrosis and at Least One F508del Allele: A Phase 3, Open-Label Clinical Trial.

Wainwright, Claire; McColley, Susanna A; McNally, Paul; Powers, Michael; Ratjen, Felix; Rayment, Jonathan H; Retsch-Bogart, George; Roesch, Erica; Ahluwalia, Neil; Chin, Anna; Chu, Chenghao; Lu, Mengdi; Menon, Prema; Waltz, David; Weinstock, Tanya; Zelazoski, Laura; Davies, Jane C.

Am J Respir Crit Care Med ; 208(1): 68-78, 2023 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-37154609

3.

What is cystic fibrosis screen positive inconclusive diagnosis? And what is it not?

Devoy, Emily; Hughes, Dominic; Alharbi, Asma Falah; Francis, Jacqueline; Davies, Jane C.

Arch Dis Child Educ Pract Ed ; 2024 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-38453427

4.

The clinical impact of Lumacaftor-Ivacaftor on structural lung disease and lung function in children aged 6-11 with cystic fibrosis in a real-world setting.

McNally, Paul; Linnane, Barry; Williamson, Michael; Elnazir, Basil; Short, Christopher; Saunders, Clare; Kirwan, Laura; David, Rea; Kemner-Van de Corput, Mariette P C; Tiddens, Harm A W M; Davies, Jane C; Cox, Des W.

Respir Res ; 24(1): 199, 2023 Aug 11.

Artigo em Inglês | MEDLINE | ID: mdl-37568199

5.

Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 Through 11 Years of Age with Cystic Fibrosis Heterozygous for F508del and a Minimal Function Mutation: A Phase 3b, Randomized, Placebo-controlled Study.

Mall, Marcus A; Brugha, Rossa; Gartner, Silvia; Legg, Julian; Moeller, Alexander; Mondejar-Lopez, Pedro; Prais, Dario; Pressler, Tacjana; Ratjen, Felix; Reix, Philippe; Robinson, Paul D; Selvadurai, Hiran; Stehling, Florian; Ahluwalia, Neil; Arteaga-Solis, Emilio; Bruinsma, Bote G; Jennings, Mark; Moskowitz, Samuel M; Noel, Sabrina; Tian, Simon; Weinstock, Tanya G; Wu, Pan; Wainwright, Claire E; Davies, Jane C.

Am J Respir Crit Care Med ; 206(11): 1361-1369, 2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-35816621

6.

Cystic fibrosis.

Shteinberg, Michal; Haq, Iram J; Polineni, Deepika; Davies, Jane C.

Lancet ; 397(10290): 2195-2211, 2021 06 05.

Artigo em Inglês | MEDLINE | ID: mdl-34090606

7.

Efficacy and safety of inhaled ENaC inhibitor BI 1265162 in patients with cystic fibrosis: BALANCE-CF 1, a randomised, phase II study.

Goss, Christopher H; Fajac, Isabelle; Jain, Raksha; Seibold, Wolfgang; Gupta, Abhya; Hsu, Ming-Chi; Sutharsan, Sivagurunathan; Davies, Jane C; Mall, Marcus A.

Eur Respir J ; 59(2)2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34385272

8.

Ivacaftor in Infants Aged 4 to <12 Months with Cystic Fibrosis and a Gating Mutation. Results of a Two-Part Phase 3 Clinical Trial.

Davies, Jane C; Wainwright, Claire E; Sawicki, Gregory S; Higgins, Mark N; Campbell, Daniel; Harris, Christopher; Panorchan, Paul; Haseltine, Eric; Tian, Simon; Rosenfeld, Margaret.

Am J Respir Crit Care Med ; 203(5): 585-593, 2021 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-33023304

9.

Pseudomonas aeruginosa in the Cystic Fibrosis Lung.

King, John; Murphy, Ronan; Davies, Jane C.

Adv Exp Med Biol ; 1386: 347-369, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36258079

10.

VX-659-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles.

Davies, Jane C; Moskowitz, Samuel M; Brown, Cynthia; Horsley, Alexander; Mall, Marcus A; McKone, Edward F; Plant, Barry J; Prais, Dario; Ramsey, Bonnie W; Taylor-Cousar, Jennifer L; Tullis, Elizabeth; Uluer, Ahmet; McKee, Charlotte M; Robertson, Sarah; Shilling, Rebecca A; Simard, Christopher; Van Goor, Fredrick; Waltz, David; Xuan, Fengjuan; Young, Tim; Rowe, Steven M.

N Engl J Med ; 379(17): 1599-1611, 2018 10 25.

Artigo em Inglês | MEDLINE | ID: mdl-30334693

11.

Transepithelial nasal potential difference in patients with, and at risk of acute respiratory distress syndrome.

Mac Sweeney, Rob; Reddy, Kiran; Davies, Jane C; Parker, Mike; Kelly, Barry; Elborn, J Stuart; Conlon, John; Verghis, Rejina M; Calfee, Carolyn S; Matthay, Michael A; Alton, Eric W F W; McAuley, Daniel F.

Thorax ; 76(11): 1099-1107, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-33888572

12.

Time to get serious about the detection and monitoring of early lung disease in cystic fibrosis.

Bayfield, Katie J; Douglas, Tonia A; Rosenow, Tim; Davies, Jane C; Elborn, Stuart J; Mall, Marcus; Paproki, Anthony; Ratjen, Felix; Sly, Peter D; Smyth, Alan R; Stick, Stephen; Wainwright, Claire E; Robinson, Paul D.

Thorax ; 76(12): 1255-1265, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-33927017

13.

Clinical pharmacokinetics and dose recommendations for posaconazole gastroresistant tablets in children with cystic fibrosis.

Bentley, Siân; Davies, Jane C; Gastine, Silke; Donovan, Jackie; Standing, Joseph F.

J Antimicrob Chemother ; 76(12): 3247-3254, 2021 11 12.

Artigo em Inglês | MEDLINE | ID: mdl-34458906

14.

Response of Pseudomonas aeruginosa to the Innate Immune System-Derived Oxidants Hypochlorous Acid and Hypothiocyanous Acid.

Farrant, Katie V; Spiga, Livia; Davies, Jane C; Williams, Huw D.

J Bacteriol ; 203(2)2020 12 18.

Artigo em Inglês | MEDLINE | ID: mdl-33106346

15.

Tezacaftor-Ivacaftor in Residual-Function Heterozygotes with Cystic Fibrosis.

Rowe, Steven M; Daines, Cori; Ringshausen, Felix C; Kerem, Eitan; Wilson, John; Tullis, Elizabeth; Nair, Nitin; Simard, Christopher; Han, Linda; Ingenito, Edward P; McKee, Charlotte; Lekstrom-Himes, Julie; Davies, Jane C.

N Engl J Med ; 377(21): 2024-2035, 2017 11 23.

Artigo em Inglês | MEDLINE | ID: mdl-29099333

16.

Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa.

Soren, Odel; Rineh, Ardeshir; Silva, Diogo G; Cai, Yuming; Howlin, Robert P; Allan, Raymond N; Feelisch, Martin; Davies, Jane C; Connett, Gary J; Faust, Saul N; Kelso, Michael J; Webb, Jeremy S.

J Antimicrob Chemother ; 75(1): 117-125, 2020 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-31682251

17.

Monitoring early stage lung disease in cystic fibrosis.

Nissenbaum, Claire; Davies, Gwyneth; Horsley, Alexander; Davies, Jane C.

Curr Opin Pulm Med ; 26(6): 671-678, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32925367

18.

Chronicity Counts: The Impact of P. aeruginosa, S. aureus, and Co-Infection in Cystic Fibrosis.

Mossop, Micaela; Ish-Horowicz, Jonathan; Hughes, Dominic; Dobra, Rebecca; Cunanan, Alessandra G; Rosenthal, Mark; Carr, Siobhán B; Ramadan, Newara; Nolan, Laura M; Davies, Jane C.

Am J Respir Crit Care Med ; 2024 Feb 29.

Artigo em Inglês | MEDLINE | ID: mdl-38422389

19.

Trials and tribulations: The highs and lows of running cystic fibrosis drug studies.

Davies, Jane C.

Paediatr Respir Rev ; 31: 25-27, 2019 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-31153791

20.

"Fortunate are those who take the first steps"? The psychosocial impact of novel drug development.

Dobra, Rebecca; Madge, Susan; Martin, Isaac; Weldon, Paul; Simmonds, Nicholas; Davies, Jane C.

Paediatr Respir Rev ; 31: 9-11, 2019 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-30975518

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