Detalhe da pesquisa
1.
Hemodynamic disturbed flow induces differential DNA methylation of endothelial Kruppel-Like Factor 4 promoter in vitro and in vivo.
Circ Res
; 115(1): 32-43, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24755985
2.
Endothelial epigenetics in biomechanical stress: disturbed flow-mediated epigenomic plasticity in vivo and in vitro.
Arterioscler Thromb Vasc Biol
; 35(6): 1317-26, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25838424
3.
Arterial endothelial methylome: differential DNA methylation in athero-susceptible disturbed flow regions in vivo.
BMC Genomics
; 16: 506, 2015 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26148682
4.
Biomechanical factors in atherosclerosis: mechanisms and clinical implications.
Eur Heart J
; 35(43): 3013-20, 3020a-3020d, 2014 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25230814
5.
Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium.
Arterioscler Thromb Vasc Biol
; 32(4): 979-87, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22267480
6.
MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro.
Proc Natl Acad Sci U S A
; 107(30): 13450-5, 2010 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-20624982
7.
Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis.
Circ Res
; 105(5): 453-61, 2009 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-19661457
8.
Hypercholesterolemia induces side-specific phenotypic changes and peroxisome proliferator-activated receptor-gamma pathway activation in swine aortic valve endothelium.
Arterioscler Thromb Vasc Biol
; 30(2): 225-31, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19926833
9.
Side-specific expression of activated leukocyte adhesion molecule (ALCAM; CD166) in pathosusceptible regions of swine aortic valve endothelium.
J Heart Valve Dis
; 20(2): 165-7, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21560815
10.
Prelesional arterial endothelial phenotypes in hypercholesterolemia: universal ABCA1 upregulation contrasts with region-specific gene expression in vivo.
Am J Physiol Heart Circ Physiol
; 298(1): H163-70, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19897713
11.
Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo.
Semin Thromb Hemost
; 36(3): 265-75, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20533180
12.
Hypercholesterolemia suppresses inwardly rectifying K+ channels in aortic endothelium in vitro and in vivo.
Circ Res
; 98(8): 1064-71, 2006 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-16556870
13.
Exploring human/animal intersections: converging lines of evidence in comparative models of aging.
Alzheimers Dement
; 4(1): 1-5, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18631944
14.
Endothelial protein kinase C isoform identity and differential activity of PKCzeta in an athero-susceptible region of porcine aorta.
Circ Res
; 97(5): 443-9, 2005 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16051884
15.
Spatial heterogeneity of endothelial phenotypes correlates with side-specific vulnerability to calcification in normal porcine aortic valves.
Circ Res
; 96(7): 792-9, 2005 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15761200
16.
Getting physical with the aortic valve.
Arterioscler Thromb Vasc Biol
; 31(3): 474-5, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325667
17.
Biofluids, cell mechanics and epigenetics: Flow-induced epigenetic mechanisms of endothelial gene expression.
J Biomech
; 50: 3-10, 2017 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27865480
18.
Spatial phenotyping of the endocardial endothelium as a function of intracardiac hemodynamic shear stress.
J Biomech
; 50: 11-19, 2017 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27916240
19.
Spatial microstimuli in endothelial mechanosignaling.
Circ Res
; 92(4): 359-70, 2003 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12623874
20.
Integrated Regional Cardiac Hemodynamic Imaging and RNA Sequencing Reveal Corresponding Heterogeneity of Ventricular Wall Shear Stress and Endocardial Transcriptome.
J Am Heart Assoc
; 5(4): e003170, 2016 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27091183