Detalhe da pesquisa
1.
PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding.
J Biol Chem
; 296: 100636, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33831417
2.
RNA-Sequencing Highlights Inflammation and Impaired Integrity of the Vascular Wall in Brain Arteriovenous Malformations.
Stroke
; 51(1): 268-274, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31795902
3.
Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo.
Hum Mol Genet
; 26(15): 2850-2863, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28453791
4.
RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture.
Stroke
; 47(5): 1286-93, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27026628
5.
Protein interactors of 3-O sulfated heparan sulfates in human MCI and age-matched control cerebrospinal fluid.
Sci Data
; 10(1): 121, 2023 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36879013
6.
The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates.
BMC Mol Cell Biol
; 23(1): 61, 2022 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36564747
7.
Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1.
Brain Behav Immun Health
; 13: 100227, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34589742
8.
Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils.
Front Aging Neurosci
; 12: 614587, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33519421
9.
Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants.
Mol Neurodegener
; 18(1): 92, 2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38017580
10.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Stem Cell Reports
; 11(2): 363-379, 2018 08 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30057263
11.
Immunologic profiles of multiple sclerosis treatments reveal shared early B cell alterations.
Neurol Neuroimmunol Neuroinflamm
; 3(4): e240, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27231713
12.
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs.
Neuron
; 90(3): 535-50, 2016 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27112497
13.
Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia.
Stem Cell Reports
; 4(1): 16-24, 2015 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25556567
14.
Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
Stem Cell Reports
; 13(2): 434-435, 2019 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31412287
15.
Progranulin does not affect motor neuron degeneration in mutant SOD1 mice and rats.
Neurobiol Aging
; 34(10): 2302-3, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23608112
16.
The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding.
Neurobiol Aging
; 34(11): 2541-7, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23706646
17.
Cellular effects of progranulin in health and disease.
J Mol Neurosci
; 45(3): 549-60, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21611805
18.
Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy.
PLoS One
; 5(10): e13368, 2010 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20967127
19.
Microglial upregulation of progranulin as a marker of motor neuron degeneration.
J Neuropathol Exp Neurol
; 69(12): 1191-200, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21107132