Detalhe da pesquisa
1.
Combined treatment with inhibitors of ErbB Receptors and Hh signaling pathways is more effective than single treatment in reducing the growth of malignant mesothelioma both in vitro and in vivo.
J Transl Med
; 20(1): 286, 2022 06 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35752861
2.
A gene dosage-dependent effect unveils NBS1 as both a haploinsufficient tumour suppressor and an essential gene for SHH-medulloblastoma.
Neuropathol Appl Neurobiol
; 48(6): e12837, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35839783
3.
Che-1/AATF binds to RNA polymerase I machinery and sustains ribosomal RNA gene transcription.
Nucleic Acids Res
; 48(11): 5891-5906, 2020 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-32421830
4.
The emerging role of the KCTD proteins in cancer.
Cell Commun Signal
; 19(1): 56, 2021 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34001146
5.
Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.
EMBO J
; 34(2): 200-17, 2015 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25476449
6.
The centrosomal deubiquitylase USP21 regulates Gli1 transcriptional activity and stability.
J Cell Sci
; 129(21): 4001-4013, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27621083
7.
Sonic Hedgehog Medulloblastoma Cancer Stem Cells Mirnome and Transcriptome Highlight Novel Functional Networks.
Int J Mol Sci
; 19(8)2018 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30096798
8.
microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1.
EMBO J
; 32(21): 2819-32, 2013 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-24076654
9.
ß-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.
BMC Cancer
; 17(1): 488, 2017 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28716052
10.
Hedgehog controls neural stem cells through p53-independent regulation of Nanog.
EMBO J
; 29(15): 2646-58, 2010 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-20581804
11.
SALL4 is a CRL3REN/KCTD11 substrate that drives Sonic Hedgehog-dependent medulloblastoma.
Cell Death Differ
; 31(2): 170-187, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38062245
12.
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.
Nat Cell Biol
; 8(12): 1415-23, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17115028
13.
The inhibition of IRE1alpha/XBP1 axis prevents EBV-driven lymphomagenesis in NSG mice.
Microbiol Spectr
; 11(6): e0263623, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37882554
14.
ß-arrestin1-E2F1-ac axis regulates physiological apoptosis and cell cycle exit in cellular models of early postnatal cerebellum.
Front Cell Dev Biol
; 11: 990711, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36923256
15.
SCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment.
Cell Death Dis
; 14(9): 616, 2023 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37730723
16.
Hedgehog-GLI and Notch Pathways Sustain Chemoresistance and Invasiveness in Colorectal Cancer and Their Inhibition Restores Chemotherapy Efficacy.
Cancers (Basel)
; 15(5)2023 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36900263
17.
Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.
Cancer Lett
; 559: 216120, 2023 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36893894
18.
Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells.
EMBO J
; 27(19): 2616-27, 2008 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-18756266
19.
Glucocorticoids and neonatal brain injury: the hedgehog connection.
J Clin Invest
; 119(2): 243-6, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19244604
20.
Islet Regeneration and Pancreatic Duct Glands in Human and Experimental Diabetes.
Front Cell Dev Biol
; 10: 814165, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35186929