Detalhe da pesquisa
1.
No Time to Relax and Unwind: Exploration of Topoisomerases and a Growing Field of Study.
Int J Mol Sci
; 24(17)2023 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37685888
2.
Inhibition of Topoisomerases by Metal Thiosemicarbazone Complexes.
Int J Mol Sci
; 24(15)2023 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37569386
3.
Adaptive Measurement of Change: A Novel Method to Reduce Respondent Burden and Detect Significant Individual-Level Change in Patient-Reported Outcome Measures.
Arch Phys Med Rehabil
; 103(5S): S43-S52, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34606759
4.
Synthesis and evaluation of etoposide and podophyllotoxin analogs against topoisomerase IIα and HCT-116 cells.
Bioorg Med Chem
; 28(22): 115773, 2020 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33035756
5.
Clarifying the Mechanism of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα and IIß.
Chem Res Toxicol
; 32(10): 2135-2143, 2019 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31512855
6.
Structural and Metal Ion Effects on Human Topoisomerase IIα Inhibition by α-(N)-Heterocyclic Thiosemicarbazones.
Chem Res Toxicol
; 32(1): 90-99, 2019 01 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30484632
7.
HU-331 and Oxidized Cannabidiol Act as Inhibitors of Human Topoisomerase IIα and ß.
Chem Res Toxicol
; 31(2): 137-144, 2018 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29272108
8.
Two-Mechanism Model for the Interaction of Etoposide Quinone with Topoisomerase IIα.
Chem Res Toxicol
; 29(9): 1541-8, 2016 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27533850
9.
Examination of the Impact of Copper(II) α-(N)-Heterocyclic Thiosemicarbazone Complexes on DNA Topoisomerase IIα.
Chem Res Toxicol
; 29(4): 649-58, 2016 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26982206
10.
A novel and unified two-metal mechanism for DNA cleavage by type II and IA topoisomerases.
Nature
; 465(7298): 641-4, 2010 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-20485342
11.
DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA.
Proc Natl Acad Sci U S A
; 109(8): 2925-30, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323612
12.
Catalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanism.
Biochemistry
; 53(41): 6595-602, 2014 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-25280269
13.
Etoposide quinone is a covalent poison of human topoisomerase IIß.
Biochemistry
; 53(19): 3229-36, 2014 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24766193
14.
HU-331 is a catalytic inhibitor of topoisomerase IIα.
Chem Res Toxicol
; 27(12): 2044-51, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25409338
15.
Faith and facts: Exploring the intersection of religion and science among anatomy educators.
Anat Sci Educ
; 2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38409570
16.
Etoposide catechol is an oxidizable topoisomerase II poison.
Chem Res Toxicol
; 26(8): 1156-8, 2013 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863110
17.
PSICalc: a novel approach to identifying and ranking critical non-proximal interdependencies within the overall protein structure.
Bioinform Adv
; 2(1): vbac058, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36699404
18.
Etoposide quinone is a redox-dependent topoisomerase II poison.
Biochemistry
; 50(25): 5660-7, 2011 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21595477
19.
The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing.
Nucleic Acids Res
; 37(3): 738-48, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19042970
20.
Cannabidiol oxidation product HU-331 is a potential anticancer cannabinoid-quinone: a narrative review.
J Cannabis Res
; 3(1): 11, 2021 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33892826