Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Efficacy of a Pseudomonas aeruginosa serogroup O9 vaccine.

Moustafa, Dina A; DiGiandomenico, Antonio; Raghuram, Vishnu; Schulman, Marc; Scarff, Jennifer M; Davis, Michael R; Varga, John J; Dean, Charles R; Goldberg, Joanna B.

Infect Immun ; 91(12): e0024723, 2023 Dec 12.

Artigo em Inglês | MEDLINE | ID: mdl-37991349

2.

In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor.

Blais, Johanne; Dean, Charles R; Lapointe, Guillaume; Leeds, Jennifer A; Ma, Sylvia; Morris, Laura; Moser, Heinz E; Osborne, Colin S; Prosen, Katherine R; Richie, Daryl; Skepper, Colin; Thompson, Katherine; Vo, Jason; Yue, Qin; Rivkin, Alexey.

Antimicrob Agents Chemother ; 66(12): e0092122, 2022 12 20.

Artigo em Inglês | MEDLINE | ID: mdl-36448795

3.

Degree of Dietary Specialization on Furanocoumarin-Containing Hostplants in a Newly Invasive Web Building Caterpillar.

Dean, Charles A E; Katz, Aron D; Wu, Wen-Yen; Berenbaum, May R.

J Chem Ecol ; 48(11-12): 850-866, 2022 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-36450872

4.

Personality Disorders as a Basis for Discharge and Denial of Benefits in the Military: Logical or Abusive?

Dean, Charles E.

J Nerv Ment Dis ; 209(3): 152-154, 2021 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-33620913

5.

Animal Models of Peripheral Pain: Biology Review and Application for Drug Discovery.

Kaliyaperumal, Saravanan; Wilson, Kristin; Aeffner, Famke; Dean, Charles.

Toxicol Pathol ; 48(1): 202-219, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31269874

6.

Mutations Reducing In Vitro Susceptibility to Novel LpxC Inhibitors in Pseudomonas aeruginosa and Interplay of Efflux and Nonefflux Mechanisms.

Jones, Adriana K; Caughlan, Ruth E; Woods, Angela L; Uehara, Kyoko; Xie, Lili; Barnes, S Whitney; Walker, John R; Thompson, Katherine V; Ranjitkar, Srijan; Lee, Patrick S; Dean, Charles R.

Antimicrob Agents Chemother ; 64(1)2019 12 20.

Artigo em Inglês | MEDLINE | ID: mdl-31658970

7.

Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Pseudomonas aeruginosa PAO1: Uncovering a New Role for MexMN-OprM in Efflux of ß-Lactams and a Novel Regulatory Circuit (MmnRS) Controlling MexMN Expression.

Ranjitkar, Srijan; Jones, Adriana K; Mostafavi, Mina; Zwirko, Zachary; Iartchouk, Oleg; Barnes, S Whitney; Walker, John R; Willis, Thomas W; Lee, Patrick S; Dean, Charles R.

Antimicrob Agents Chemother ; 63(2)2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30420483

8.

Neural circuitry and precision medicines for mental disorders: are they compatible?

Dean, Charles E.

Psychol Med ; 49(1): 1-8, 2019 01.

Artigo em Inglês | MEDLINE | ID: mdl-30409236

9.

Whither Research Domain Criteria?

Dean, Charles E.

J Nerv Ment Dis ; 207(6): 419-420, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-31157690

10.

Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine.

Bussiere, Jeanine L; Davies, Rhian; Dean, Charles; Xu, Cen; Kim, Kyung Hoon; Vargas, Hugo M; Chellman, Gary J; Balasubramanian, Ganesh; Rubio-Beltran, Eloisa; MaassenVanDenBrink, Antoinette; Monticello, Thomas M.

Regul Toxicol Pharmacol ; 106: 224-238, 2019 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-31085251

11.

Impact of Inducible bla_DHA-1 on Susceptibility of Klebsiella pneumoniae Clinical Isolates to LYS228 and Identification of Chromosomal mpl and ampD Mutations Mediating Upregulation of Plasmid-Borne bla_DHA-1 Expression.

Jones, Adriana K; Ranjitkar, Srijan; Lopez, Sara; Li, Cindy; Blais, Johanne; Reck, Folkert; Dean, Charles R.

Antimicrob Agents Chemother ; 62(10)2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-30061296

12.

In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae.

Blais, Johanne; Lopez, Sara; Li, Cindy; Ruzin, Alexey; Ranjitkar, Srijan; Dean, Charles R; Leeds, Jennifer A; Casarez, Anthony; Simmons, Robert L; Reck, Folkert.

Antimicrob Agents Chemother ; 62(10)2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-30038040

13.

Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae.

Dean, Charles R; Barkan, David T; Bermingham, Alun; Blais, Johanne; Casey, Fergal; Casarez, Anthony; Colvin, Richard; Fuller, John; Jones, Adriana K; Li, Cindy; Lopez, Sara; Metzger, Louis E; Mostafavi, Mina; Prathapam, Ramadevi; Rasper, Dita; Reck, Folkert; Ruzin, Alexey; Shaul, Jacob; Shen, Xiaoyu; Simmons, Robert L; Skewes-Cox, Peter; Takeoka, Kenneth T; Tamrakar, Pramila; Uehara, Tsuyoshi; Wei, Jun-Rong.

Antimicrob Agents Chemother ; 62(10)2018 10.

Artigo em Inglês | MEDLINE | ID: mdl-30061293

14.

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.

Reck, Folkert; Bermingham, Alun; Blais, Johanne; Capka, Vladimir; Cariaga, Taryn; Casarez, Anthony; Colvin, Richard; Dean, Charles R; Fekete, Alex; Gong, Wanben; Growcott, Ellie; Guo, Hongqiu; Jones, Adriana K; Li, Cindy; Li, Fengxia; Lin, Xiaodong; Lindvall, Mika; Lopez, Sara; McKenney, David; Metzger, Louis; Moser, Heinz E; Prathapam, Ramadevi; Rasper, Dita; Rudewicz, Patrick; Sethuraman, Vijay; Shen, Xiaoyu; Shaul, Jacob; Simmons, Robert L; Tashiro, Kyuto; Tang, Dazhi; Tjandra, Meiliana; Turner, Nancy; Uehara, Tsuyoshi; Vitt, Charles; Whitebread, Steven; Yifru, Aregahegn; Zang, Xu; Zhu, Qingming.

Bioorg Med Chem Lett ; 28(4): 748-755, 2018 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-29336873

15.

Determinants of Antibacterial Spectrum and Resistance Potential of the Elongation Factor G Inhibitor Argyrin B in Key Gram-Negative Pathogens.

Jones, Adriana K; Woods, Angela L; Takeoka, Kenneth T; Shen, Xiaoyu; Wei, Jun-Rong; Caughlan, Ruth E; Dean, Charles R.

Antimicrob Agents Chemother ; 61(4)2017 04.

Artigo em Inglês | MEDLINE | ID: mdl-28096160

16.

Etelcalcetide, A Novel Calcimimetic, Prevents Vascular Calcification in A Rat Model of Renal Insufficiency with Secondary Hyperparathyroidism.

Yu, Longchuan; Tomlinson, James E; Alexander, Shawn T; Hensley, Kelly; Han, Chun-Ya; Dwyer, Denise; Stolina, Marina; Dean, Charles; Goodman, William G; Richards, William G; Li, Xiaodong.

Calcif Tissue Int ; 101(6): 641-653, 2017 12.

Artigo em Inglês | MEDLINE | ID: mdl-29038882

17.

Nonclinical Safety Profile of Etelcalcetide, a Novel Peptide Calcimimetic for the Treatment of Secondary Hyperparathyroidism.

Fielden, Mark R; Dean, Charles; Black, Kurt; Sawant, Satin G; Subramanian, Raju; Tomlinson, James E; Walter, Sarah; Zimmermann, Cameron; Griggs, Mark W; McKeon, Marie E; Lewis, Elise M; Beevers, Carol; Pyrah, Ian.

Int J Toxicol ; 35(3): 294-308, 2016 05.

Artigo em Inglês | MEDLINE | ID: mdl-26941242

18.

Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis.

Bojkovic, Jade; Richie, Daryl L; Six, David A; Rath, Christopher M; Sawyer, William S; Hu, Qijun; Dean, Charles R.

J Bacteriol ; 198(4): 731-41, 2015 Dec 14.

Artigo em Inglês | MEDLINE | ID: mdl-26668262

19.

A quantitative measure of handwriting dysfluency for assessing tardive dyskinesia.

Caligiuri, Michael P; Teulings, Hans-Leo; Dean, Charles E; Lohr, James B.

J Clin Psychopharmacol ; 35(2): 168-74, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25679121

20.

Discovery of 2-methylpyridine-based biaryl amides as Î³-secretase modulators for the treatment of Alzheimer's disease.

Chen, Jian Jeffrey; Qian, Wenyuan; Biswas, Kaustav; Yuan, Chester; Amegadzie, Albert; Liu, Qingyian; Nixey, Thomas; Zhu, Joe; Ncube, Mqhele; Rzasa, Robert M; Chavez, Frank; Chen, Ning; DeMorin, Frenel; Rumfelt, Shannon; Tegley, Christopher M; Allen, Jennifer R; Hitchcock, Stephen; Hungate, Randy; Bartberger, Michael D; Zalameda, Leeanne; Liu, Yichin; McCarter, John D; Zhang, Jianhua; Zhu, Li; Babu-Khan, Safura; Luo, Yi; Bradley, Jodi; Wen, Paul H; Reid, Darren L; Koegler, Frank; Dean, Charles; Hickman, Dean; Correll, Tiffany L; Williamson, Toni; Wood, Stephen.

Bioorg Med Chem Lett ; 23(23): 6447-54, 2013 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-24139583

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Efficacy of a Pseudomonas aeruginosa serogroup O9 vaccine.

In Vitro and In Vivo Properties of CUO246, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor.

Degree of Dietary Specialization on Furanocoumarin-Containing Hostplants in a Newly Invasive Web Building Caterpillar.

Personality Disorders as a Basis for Discharge and Denial of Benefits in the Military: Logical or Abusive?

Animal Models of Peripheral Pain: Biology Review and Application for Drug Discovery.

Mutations Reducing In Vitro Susceptibility to Novel LpxC Inhibitors in Pseudomonas aeruginosa and Interplay of Efflux and Nonefflux Mechanisms.

Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Pseudomonas aeruginosa PAO1: Uncovering a New Role for MexMN-OprM in Efflux of ß-Lactams and a Novel Regulatory Circuit (MmnRS) Controlling MexMN Expression.

Neural circuitry and precision medicines for mental disorders: are they compatible?

Whither Research Domain Criteria?

Nonclinical safety evaluation of erenumab, a CGRP receptor inhibitor for the prevention of migraine.

Impact of Inducible bla_DHA-1 on Susceptibility of Klebsiella pneumoniae Clinical Isolates to LYS228 and Identification of Chromosomal mpl and ampD Mutations Mediating Upregulation of Plasmid-Borne bla_DHA-1 Expression.

In Vitro Activity of LYS228, a Novel Monobactam Antibiotic, against Multidrug-Resistant Enterobacteriaceae.

Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae.

Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae - Identification of LYS228.

Determinants of Antibacterial Spectrum and Resistance Potential of the Elongation Factor G Inhibitor Argyrin B in Key Gram-Negative Pathogens.

Etelcalcetide, A Novel Calcimimetic, Prevents Vascular Calcification in A Rat Model of Renal Insufficiency with Secondary Hyperparathyroidism.

Nonclinical Safety Profile of Etelcalcetide, a Novel Peptide Calcimimetic for the Treatment of Secondary Hyperparathyroidism.

Characterization of an Acinetobacter baumannii lptD Deletion Strain: Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis.

A quantitative measure of handwriting dysfluency for assessing tardive dyskinesia.

Discovery of 2-methylpyridine-based biaryl amides as Î³-secretase modulators for the treatment of Alzheimer's disease.