Detalhe da pesquisa
1.
YAP1 is essential for malignant mesothelioma tumor maintenance.
BMC Cancer
; 22(1): 639, 2022 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35689194
2.
Prostaglandin EP2 receptor signaling protects human trabecular meshwork cells from apoptosis induced by ER stress through down-regulation of p53.
Biochim Biophys Acta
; 1863(9): 2322-32, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27321910
3.
Discovery, Structure Elucidation, and Biological Characterization of Nannocystinâ A, a Macrocyclic Myxobacterial Metabolite with Potent Antiproliferative Properties.
Angew Chem Int Ed Engl
; 54(35): 10145-8, 2015 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26031409
4.
Production of the Bengamide Class of Marine Natural Products in Myxobacteria: Biosynthesis and Structure-Activity Relationships.
Angew Chem Int Ed Engl
; 54(51): 15560-4, 2015 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26514647
5.
Genome-wide CRISPR Screen Reveals RAB10 as a Synthetic Lethal Gene in Colorectal and Pancreatic Cancers Carrying SMAD4 Loss.
Cancer Res Commun
; 3(5): 780-792, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37377893
6.
TEAD Inhibitors Sensitize KRASG12C Inhibitors via Dual Cell Cycle Arrest in KRASG12C-Mutant NSCLC.
Pharmaceuticals (Basel)
; 16(4)2023 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37111311
7.
KRAS G12C fragment screening renders new binding pockets.
Small GTPases
; 13(1): 225-238, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34558391
8.
Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 Inhibition.
SLAS Discov
; 26(7): 922-932, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33896272
9.
SAR439859, a Novel Selective Estrogen Receptor Degrader (SERD), Demonstrates Effective and Broad Antitumor Activity in Wild-Type and Mutant ER-Positive Breast Cancer Models.
Mol Cancer Ther
; 20(2): 250-262, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33310762
10.
Efficacy of the MDM2 Inhibitor SAR405838 in Glioblastoma Is Limited by Poor Distribution Across the Blood-Brain Barrier.
Mol Cancer Ther
; 17(9): 1893-1901, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29970480
11.
Correction: SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma.
Clin Cancer Res
; 28(2): 431, 2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35045964
12.
P53 activation inhibits all types of hematopoietic progenitors and all stages of megakaryopoiesis.
Oncotarget
; 7(22): 31980-92, 2016 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26959882
13.
SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma.
Clin Cancer Res
; 22(5): 1150-60, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26475335
14.
Elucidation of Acquired Resistance to Bcl-2 and MDM2 Inhibitors in Acute Leukemia In Vitro and In Vivo.
Clin Cancer Res
; 21(11): 2558-68, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25754349
15.
Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment.
PLoS One
; 10(6): e0128807, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26070072
16.
SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression.
Cancer Res
; 74(20): 5855-65, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25145672
17.
Anti-insulin-like growth factor 1 receptor antibody EM164 (murine AVE1642) exhibits anti-tumour activity alone and in combination with temozolomide against neuroblastoma.
Eur J Cancer
; 46(18): 3251-62, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20591650
18.
Inhibition of the Ras-Net (Elk-3) pathway by a novel pyrazole that affects microtubules.
Cancer Res
; 68(5): 1275-83, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18316589
19.
CD45neg but not CD45pos human myeloma cells are sensitive to the inhibition of IGF-1 signaling by a murine anti-IGF-1R monoclonal antibody, mAVE1642.
J Immunol
; 177(6): 4218-23, 2006 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16951388