Detalhe da pesquisa
1.
ADH1B, the adipocyte-enriched alcohol dehydrogenase, plays an essential, cell-autonomous role in human adipogenesis.
Proc Natl Acad Sci U S A
; 121(24): e2319301121, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38838011
2.
Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases.
Int J Mol Sci
; 24(2)2023 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36674751
3.
Effect of CFTR correctors on the traffic and the function of intracellularly retained ABCB4 variants.
Liver Int
; 41(6): 1344-1357, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33650203
4.
Molecular Regulation of Canalicular ABC Transporters.
Int J Mol Sci
; 22(4)2021 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33672718
5.
RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic.
Int J Mol Sci
; 22(13)2021 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34209301
6.
Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease.
J Hepatol
; 72(4): 627-635, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31760070
7.
Functional rescue of an ABCB11 mutant by ivacaftor: A new targeted pharmacotherapy approach in bile salt export pump deficiency.
Liver Int
; 40(8): 1917-1925, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32433800
8.
Expanding the mutational spectrum of the ABCB4 gene in inherited adult cholestatic liver disorders with four novel pathogenic variants.
Rev Esp Enferm Dig
; 111(1): 76-79, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30449124
9.
Functional defect of variants in the adenosine triphosphate-binding sites of ABCB4 and their rescue by the cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor (VX-770).
Hepatology
; 65(2): 560-570, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28012258
10.
A functional classification of ABCB4 variations causing progressive familial intrahepatic cholestasis type 3.
Hepatology
; 63(5): 1620-31, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26474921
11.
Oligomerization is required for normal endocytosis/transcytosis of a GPI-anchored protein in polarized hepatic cells.
J Cell Sci
; 126(Pt 15): 3409-16, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23750006
12.
Phosphorylation of ABCB4 impacts its function: insights from disease-causing mutations.
Hepatology
; 60(2): 610-21, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24723470
13.
Effects of cellular, chemical, and pharmacological chaperones on the rescue of a trafficking-defective mutant of the ATP-binding cassette transporter proteins ABCB1/ABCB4.
J Biol Chem
; 287(7): 5070-8, 2012 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22184139
14.
The Ca2+- and phospholipid-binding protein Annexin A2 is able to increase and decrease plasma membrane order.
Biochim Biophys Acta Biomembr
; 1864(1): 183810, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699769
15.
MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression.
Cells
; 11(4)2022 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35203270
16.
The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes.
iScience
; 25(10): 105166, 2022 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36204273
17.
A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.
Hepatology
; 49(4): 1218-27, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19185004
18.
Differential solubilization of inner plasma membrane leaflet components by Lubrol WX and Triton X-100.
Biochim Biophys Acta
; 1778(1): 105-12, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17976531
19.
Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models.
Sci Rep
; 9(1): 6653, 2019 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31040306
20.
Comparison of in silico prediction and experimental assessment of ABCB4 variants identified in patients with biliary diseases.
Int J Biochem Cell Biol
; 89: 101-109, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28587926