Detalhe da pesquisa
1.
Polygenic Risk Scores Validated in Patient-Derived Cells Stratify for Mitochondrial Subtypes of Parkinson's Disease.
Ann Neurol
; 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38767023
2.
DYT-THAP1: exploring gene expression in fibroblasts for potential biomarker discovery.
Neurogenetics
; 25(2): 141-147, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38498291
3.
Mitochondrial DNA heteroplasmy distinguishes disease manifestation in PINK1/PRKN-linked Parkinson's disease.
Brain
; 146(7): 2753-2765, 2023 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36478228
4.
Comparison of two protocols for the generation of iPSC-derived human astrocytes.
Biol Proced Online
; 25(1): 26, 2023 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37730545
5.
Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state.
Brain
; 145(3): 964-978, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34919646
6.
Discordant Monozygotic Parkinson Disease Twins: Role of Mitochondrial Integrity.
Ann Neurol
; 89(1): 158-164, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33094862
7.
Parkin Deficiency Impairs Mitochondrial DNA Dynamics and Propagates Inflammation.
Mov Disord
; 37(7): 1405-1415, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35460111
8.
Mitochondrial damage-associated inflammation highlights biomarkers in PRKN/PINK1 parkinsonism.
Brain
; 143(10): 3041-3051, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33029617
9.
Integration of VDR genome wide binding and GWAS genetic variation data reveals co-occurrence of VDR and NF-κB binding that is linked to immune phenotypes.
BMC Genomics
; 18(1): 132, 2017 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28166722
10.
Stable Isotope-Assisted Evaluation of Different Extraction Solvents for Untargeted Metabolomics of Plants.
Int J Mol Sci
; 17(7)2016 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27367667
11.
Mitochondrial DNA Deletions Discriminate Affected from Unaffected LRRK2 Mutation Carriers.
Ann Neurol
; 86(2): 324-326, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31148195
12.
Novel insights into Parkin-mediated mitochondrial dysfunction and neuroinflammation in Parkinson's disease.
Curr Opin Neurobiol
; 80: 102720, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37023495
13.
Molecular phenotypes of mitochondrial dysfunction in clinically non-manifesting heterozygous PRKN variant carriers.
NPJ Parkinsons Dis
; 9(1): 65, 2023 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37072441
14.
Genome-wide case-only analysis of gene-gene interactions with known Parkinson's disease risk variants reveals link between LRRK2 and SYT10.
NPJ Parkinsons Dis
; 9(1): 102, 2023 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37386035
15.
Impairment of neuronal mitochondrial function by L-DOPA in the absence of oxygen-dependent auto-oxidation and oxidative cell damage.
Cell Death Discov
; 7(1): 151, 2021 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34226525
16.
iPSC-Derived Microglia as a Model to Study Inflammation in Idiopathic Parkinson's Disease.
Front Cell Dev Biol
; 9: 740758, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34805149
17.
Mitochondrial Mechanisms of LRRK2 G2019S Penetrance.
Front Neurol
; 11: 881, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32982917
18.
Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy.
Sci Rep
; 10(1): 16736, 2020 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33028849