Detalhe da pesquisa
1.
Trapping of a Polyketide Synthase Module after C-C Bond Formation Reveals Transient Acyl Carrier Domain Interactions.
Angew Chem Int Ed Engl
; 63(9): e202315850, 2024 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38134222
2.
Reconstitution of polythioamide antibiotic backbone formation reveals unusual thiotemplated assembly strategy.
Proc Natl Acad Sci U S A
; 117(16): 8850-8858, 2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32265283
3.
Analysis of Rhizonin Biosynthesis Reveals Origin of Pharmacophoric Furylalanine Moieties in Diverse Cyclopeptides.
Angew Chem Int Ed Engl
; 62(42): e202308540, 2023 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37650335
4.
Ribosome-independent peptide biosynthesis: the challenge of a unifying nomenclature.
Nat Prod Rep
; 39(3): 453-459, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34586117
5.
A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria.
Angew Chem Int Ed Engl
; 61(37): e202206168, 2022 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35852818
6.
An Unexpected Split-Merge Pathway in the Assembly of the Symmetric Nonribosomal Peptide Antibiotic Closthioamide.
Angew Chem Int Ed Engl
; 60(8): 4104-4109, 2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33119936
7.
Enzyme-Primed Native Chemical Ligation Produces Autoinducing Cyclopeptides in Clostridia.
Angew Chem Int Ed Engl
; 60(19): 10670-10679, 2021 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33625794
8.
Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals Tailoring Strategy for Nonribosomal Peptide Backbones.
Angew Chem Int Ed Engl
; 58(37): 13014-13018, 2019 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276268
9.
Genome Editing Reveals Novel Thiotemplated Assembly of Polythioamide Antibiotics in Anaerobic Bacteria.
Angew Chem Int Ed Engl
; 57(43): 14080-14084, 2018 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30193003
10.
Heterocomplex structure of a polyketide synthase component involved in modular backbone halogenation.
Structure
; 31(5): 565-572.e4, 2023 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36917986