Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

A mathematical, classical stratification modeling approach to disentangling the impact of weather on infectious diseases: A case study using spatio-temporally disaggregated Campylobacter surveillance data for England and Wales.

Lo Iacono, Giovanni; Cook, Alasdair J C; Derks, Gianne; Fleming, Lora E; French, Nigel; Gillingham, Emma L; Gonzalez Villeta, Laura C; Heaviside, Clare; La Ragione, Roberto M; Leonardi, Giovanni; Sarran, Christophe E; Vardoulakis, Sotiris; Senyah, Francis; van Vliet, Arnoud H M; Nichols, Gordon.

PLoS Comput Biol ; 20(1): e1011714, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38236828

2.

A mathematical analysis of rebound in a target-mediated drug disposition model: II. With feedback.

Aston, Philip J; Derks, Gianne; Agoram, Balaji M; van der Graaf, Piet H.

J Math Biol ; 75(1): 33-84, 2017 07.

Artigo em Inglês | MEDLINE | ID: mdl-27832321

3.

A mathematical analysis of rebound in a target-mediated drug disposition model: I.without feedback.

Aston, Philip J; Derks, Gianne; Agoram, Balaji M; van der Graaf, Piet H.

J Math Biol ; 68(6): 1453-78, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-23591581

4.

A Spatially Resolved Mechanistic Growth Law for Cancer Drug Development Predicting Tumor Growing Fractions.

Nasim, Adam; Yates, James; Derks, Gianne; Dunlop, Carina.

Cancer Res Commun ; 2(8): 754-761, 2022 08.

Artigo em Inglês | MEDLINE | ID: mdl-36923310

5.

Mathematical analysis of the pharmacokinetic-pharmacodynamic (PKPD) behaviour of monoclonal antibodies: predicting in vivo potency.

Aston, Philip J; Derks, Gianne; Raji, Adewale; Agoram, Balaji M; van der Graaf, Piet H.

J Theor Biol ; 281(1): 113-21, 2011 Jul 21.

Artigo em Inglês | MEDLINE | ID: mdl-21557949

6.

Best Practices to Maximize the Use and Reuse of Quantitative and Systems Pharmacology Models: Recommendations From the United Kingdom Quantitative and Systems Pharmacology Network.

Cucurull-Sanchez, Lourdes; Chappell, Michael J; Chelliah, Vijayalakshmi; Amy Cheung, S Y; Derks, Gianne; Penney, Mark; Phipps, Alex; Malik-Sheriff, Rahuman S; Timmis, Jon; Tindall, Marcus J; van der Graaf, Piet H; Vicini, Paolo; Yates, James W T.

CPT Pharmacometrics Syst Pharmacol ; 8(5): 259-272, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30667172

7.

Predicting tyrosinaemia: a mathematical model of 4-hydroxyphenylpyruvate dioxygenase inhibition by nitisinone in rats.

Ward, John P; Dunster, Joanne L; Derks, Gianne; Mistry, Pratibha; Salazar, José D.

Math Med Biol ; 34(3): 335-390, 2017 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-27305933

8.

Modelling changes in sleep timing and duration across the lifespan: Changes in circadian rhythmicity or sleep homeostasis?

Skeldon, Anne C; Derks, Gianne; Dijk, Derk-Jan.

Sleep Med Rev ; 28: 96-107, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-26545247

9.

Mathematical models for sleep-wake dynamics: comparison of the two-process model and a mutual inhibition neuronal model.

Skeldon, Anne C; Dijk, Derk-Jan; Derks, Gianne.

PLoS One ; 9(8): e103877, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-25084361

10.

Comment on "mechanism of branching in negative ionization fronts".

Ebert, Ute; Derks, Gianne.

Phys Rev Lett ; 101(13): 139501; author reply 139502, 2008 Sep 26.

Artigo em Inglês | MEDLINE | ID: mdl-18851502

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