Detalhe da pesquisa
1.
Acceptability of a Dapivirine/Placebo Gel Administered Rectally to HIV-1 Seronegative Adults (MTN-026).
AIDS Behav
; 26(5): 1333-1346, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-34657218
2.
Safety and Efficacy of a Dapivirine Vaginal Ring for HIV Prevention in Women.
N Engl J Med
; 375(22): 2133-2143, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27959766
3.
Novel Application of Hot Melt Extrusion for the Manufacturing of Vaginal Films Containing Microbicide Candidate Dapivirine.
AAPS PharmSciTech
; 20(6): 239, 2019 Jun 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31243640
4.
Formulation and characterization of polymeric films containing combinations of antiretrovirals (ARVs) for HIV prevention.
Pharm Res
; 32(2): 458-68, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25079391
5.
Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention.
Pharm Res
; 32(11): 3768-81, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26078001
6.
Increased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir.
Mol Pharm
; 11(5): 1533-41, 2014 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24693866
7.
Phase 1 randomized trials to assess safety, pharmacokinetics, and vaginal bleeding associated with use of extended duration dapivirine and levonorgestrel vaginal rings.
PLoS One
; 19(6): e0304552, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38838028
8.
Refining the in vitro release test method for a dapivirine-releasing vaginal ring to match in vivo performance.
Drug Deliv Transl Res
; 13(8): 2072-2082, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34674162
9.
Participant experiences with a multipurpose vaginal ring for HIV and pregnancy prevention during a phase 1 clinical trial: learning from users to improve acceptability.
Front Reprod Health
; 5: 1147628, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37484873
10.
In vitro drug release, mechanical performance and stability testing of a custom silicone elastomer vaginal ring releasing dapivirine and levonorgestrel.
Int J Pharm X
; 4: 100112, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35128382
11.
A Randomized, Double Blind, Placebo-Controlled, Phase 1 Safety, and Pharmacokinetic Study of Dapivirine Gel (0.05%) Administered Rectally to HIV-1 Seronegative Adults (MTN-026).
AIDS Res Hum Retroviruses
; 38(4): 257-268, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-34498980
12.
Silicone elastomer formulations for improved performance of a multipurpose vaginal ring releasing dapivirine and levonorgestrel.
Int J Pharm X
; 3: 100091, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34977558
13.
Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings.
Int J Pharm X
; 3: 100081, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34027386
14.
Phase 1 pharmacokinetics and safety study of extended duration dapivirine vaginal rings in the United States.
J Int AIDS Soc
; 24(6): e25747, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34118115
15.
Safety, adherence, and HIV-1 seroconversion among women using the dapivirine vaginal ring (DREAM): an open-label, extension study.
Lancet HIV
; 8(2): e77-e86, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33539761
16.
Acceptability of a Dapivirine Gel Administered Rectally to HIV-1 Seronegative Adults (MTN-033 Study).
AIDS Educ Prev
; 33(5): 361-376, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34596427
17.
Dapivirine-releasing vaginal rings produced by plastic freeforming additive manufacturing.
Int J Pharm
; 572: 118725, 2019 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31648014
18.
Design of Poly(lactic-co-glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis.
Pharmaceutics
; 11(4)2019 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-30995761
19.
Drug stability and product performance characteristics of a dapivirine-releasing vaginal ring under simulated real-world conditions.
Int J Pharm
; 565: 351-357, 2019 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-31085254
20.
Mechanical testing methods for drug-releasing vaginal rings.
Int J Pharm
; 559: 182-191, 2019 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30668990