Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.

Tomkins, James E; Dihanich, Sybille; Beilina, Alexandra; Ferrari, Raffaele; Ilacqua, Nicolò; Cookson, Mark R; Lewis, Patrick A; Manzoni, Claudia.

Proteomics ; 18(10): e1700444, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29513927

2.

Inhibition of LRRK2 kinase activity stimulates macroautophagy.

Manzoni, Claudia; Mamais, Adamantios; Dihanich, Sybille; Abeti, Rosella; Soutar, Marc P M; Plun-Favreau, Helene; Giunti, Paola; Tooze, Sharon A; Bandopadhyay, Rina; Lewis, Patrick A.

Biochim Biophys Acta ; 1833(12): 2900-2910, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-23916833

3.

Rare variants in LRRK1 and Parkinson's disease.

Schulte, Eva C; Ellwanger, Daniel C; Dihanich, Sybille; Manzoni, Claudia; Stangl, Katrin; Schormair, Barbara; Graf, Elisabeth; Eck, Sebastian; Mollenhauer, Brit; Haubenberger, Dietrich; Pirker, Walter; Zimprich, Alexander; Brücke, Thomas; Lichtner, Peter; Peters, Annette; Gieger, Christian; Trenkwalder, Claudia; Mewes, Hans-Werner; Meitinger, Thomas; Lewis, Patrick A; Klünemann, Hans H; Winkelmann, Juliane.

Neurogenetics ; 15(1): 49-57, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24241507

4.

Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases.

Mamais, Adamantios; Raja, Meera; Manzoni, Claudia; Dihanich, Sybille; Lees, Andrew; Moore, Darren; Lewis, Patrick A; Bandopadhyay, Rina.

Neurobiol Dis ; 58: 183-90, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-23747310

5.

Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation.

Manzoni, Claudia; Mamais, Adamantios; Dihanich, Sybille; McGoldrick, Phillip; Devine, Michael J; Zerle, Julia; Kara, Eleanna; Taanman, Jan-Willem; Healy, Daniel G; Marti-Masso, Jose-Felix; Schapira, Anthony H; Plun-Favreau, Helene; Tooze, Sharon; Hardy, John; Bandopadhyay, Rina; Lewis, Patrick A.

Biochem Biophys Res Commun ; 441(4): 862-6, 2013 Nov 29.

Artigo em Inglês | MEDLINE | ID: mdl-24211199

6.

MASL1: a neglected ROCO protein.

Dihanich, Sybille.

Biochem Soc Trans ; 40(5): 1090-4, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22988871

7.

Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease.

Kielar, Catherine; Wishart, Thomas M; Palmer, Alice; Dihanich, Sybille; Wong, Andrew M; Macauley, Shannon L; Chan, Chun-Hung; Sands, Mark S; Pearce, David A; Cooper, Jonathan D; Gillingwater, Thomas H.

Hum Mol Genet ; 18(21): 4066-80, 2009 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-19640925

8.

mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition.

Manzoni, Claudia; Mamais, Adamantios; Dihanich, Sybille; Soutar, Marc P M; Plun-Favreau, Helene; Bandopadhyay, Rina; Abeti, Rosella; Giunti, Paola; Hardy, John; R Cookson, Mark; Tooze, Sharon A; Lewis, Patrick A.

Biosci Rep ; 38(2)2018 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-29563162

9.

LRRK2: a problem lurking in vesicle trafficking?

Dihanich, Sybille; Manzoni, Claudia.

J Neurosci ; 31(27): 9787-8, 2011 Jul 06.

Artigo em Inglês | MEDLINE | ID: mdl-21734269

10.

Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons.

Parviainen, Lotta; Dihanich, Sybille; Anderson, Greg W; Wong, Andrew M; Brooks, Helen R; Abeti, Rosella; Rezaie, Payam; Lalli, Giovanna; Pope, Simon; Heales, Simon J; Mitchison, Hannah M; Williams, Brenda P; Cooper, Jonathan D.

Acta Neuropathol Commun ; 5(1): 74, 2017 10 17.

Artigo em Inglês | MEDLINE | ID: mdl-29041969

11.

mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1.

Manzoni, Claudia; Mamais, Adamantios; Roosen, Dorien A; Dihanich, Sybille; Soutar, Marc P M; Plun-Favreau, Helene; Bandopadhyay, Rina; Hardy, John; Tooze, Sharon A; Cookson, Mark R; Lewis, Patrick A.

Sci Rep ; 6: 35106, 2016 10 12.

Artigo em Inglês | MEDLINE | ID: mdl-27731364

12.

Genetic, structural, and molecular insights into the function of ras of complex proteins domains.

Civiero, Laura; Dihanich, Sybille; Lewis, Patrick A; Greggio, Elisa.

Chem Biol ; 21(7): 809-18, 2014 Jul 17.

Artigo em Inglês | MEDLINE | ID: mdl-24981771

13.

GTP binding controls complex formation by the human ROCO protein MASL1.

Dihanich, Sybille; Civiero, Laura; Manzoni, Claudia; Mamais, Adamantios; Bandopadhyay, Rina; Greggio, Elisa; Lewis, Patrick A.

FEBS J ; 281(1): 261-74, 2014 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24286120

14.

Regional brain atrophy in mouse models of neuronal ceroid lipofuscinosis: a new rostrocaudal perspective.

Kühl, Thomas G; Dihanich, Sybille; Wong, Andrew M S; Cooper, Jonathan D.

J Child Neurol ; 28(9): 1117-22, 2013 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-24014506

15.

GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1.

Jebelli, Joseph D; Dihanich, Sybille; Civiero, Laura; Manzoni, Claudia; Greggio, Elisa; Lewis, Patrick A.

Sci Rep ; 2: 695, 2012.

Artigo em Inglês | MEDLINE | ID: mdl-23019516

Portal de Pesquisa da BVS Enfermagem

Informação e Conhecimento para a Saúde

Configurar filtros

Sua seleção (0)

Formato de exportação:

Exportar: