Detalhe da pesquisa
1.
The human pre-replication complex is an open complex.
Cell
; 186(1): 98-111.e21, 2023 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36608662
2.
Insights into 4-hydroxyphenylpyruvate dioxygenase-inhibitor interactions from comparative structural biology.
Trends Biochem Sci
; 48(6): 568-584, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36959016
3.
ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2).
Mol Cell
; 73(3): 458-473.e7, 2019 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30581148
4.
Discovery of Subnanomolar Inhibitors of 4-Hydroxyphenylpyruvate Dioxygenase via Structure-Based Rational Design.
J Agric Food Chem
; 71(2): 1170-1177, 2023 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36599124
5.
Cryo-EM structure of TMEM63C suggests it functions as a monomer.
Nat Commun
; 14(1): 7265, 2023 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37945568
6.
Molecular insights into the mechanism of 4-hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X-ray crystallography and computational simulations.
FEBS J
; 286(5): 975-990, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30632699
7.
Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2.
Nat Commun
; 10(1): 829, 2019 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30783101
8.
ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.
Nat Commun
; 8(1): 757, 2017 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28970484