Detalhe da pesquisa
1.
FASN negatively regulates p65 expression by reducing its stability via Thr254 phosphorylation and isomerization by Pin1.
J Lipid Res
; 65(4): 100529, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467328
2.
Translation initiation factor eIF3a regulates glucose metabolism and cell proliferation via promoting small GTPase Rheb synthesis and AMPK activation.
J Biol Chem
; 298(7): 102044, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35595099
3.
A novel survivin dimerization inhibitor without a labile hydrazone linker induces spontaneous apoptosis and synergizes with docetaxel in prostate cancer cells.
Bioorg Med Chem
; 65: 116761, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35504208
4.
Translational regulation of Chk1 expression by eIF3a via interaction with the RNA-binding protein HuR.
Biochem J
; 477(10): 1939-1950, 2020 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32391557
5.
Single-nucleotide polymorphisms in a short basic motif in the ABC transporter ABCG2 disable its trafficking out of endoplasmic reticulum and reduce cell resistance to anticancer drugs.
J Biol Chem
; 294(52): 20222-20232, 2019 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31719146
6.
FASN regulates cellular response to genotoxic treatments by increasing PARP-1 expression and DNA repair activity via NF-κB and SP1.
Proc Natl Acad Sci U S A
; 113(45): E6965-E6973, 2016 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791122
7.
Corrigendum to "A novel survivin dimerization inhibitor without a labile hydrazone linker induces spontaneous apoptosis and synergizes with docetaxel in prostate cancer cells" [Bioorg. Med. Chem. 65 (2022) 116761].
Bioorg Med Chem
; 78: 117127, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36517371
8.
Reversible epigenetic regulation of 14-3-3σ expression in acquired gemcitabine resistance by uhrf1 and DNA methyltransferase 1.
Mol Pharmacol
; 86(5): 561-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25189999
9.
Spectrin domain of eukaryotic initiation factor 3a is the docking site for formation of the a:b:i:g subcomplex.
J Biol Chem
; 288(39): 27951-9, 2013 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23921387
10.
Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide production.
J Lipid Res
; 54(3): 776-785, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23319743
11.
Translational regulation of RPA2 via internal ribosomal entry site and by eIF3a.
Carcinogenesis
; 34(6): 1224-31, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23393223
12.
Profibrotic effect of interleukin-18 in HK-2 cells is dependent on stimulation of the Toll-like receptor 4 (TLR4) promoter and increased TLR4 expression.
J Biol Chem
; 287(48): 40391-9, 2012 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-23027874
13.
Reversible promoter demethylation of PDGFD confers gemcitabine resistance through STAT3 activation and RRM1 upregulation.
Cancer Lett
; 567: 216266, 2023 07 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37321532
14.
eIF3a regulation of mTOR signaling and translational control via HuR in cellular response to DNA damage.
Oncogene
; 41(17): 2431-2443, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35279705
15.
Therapeutic Activity of the Lansoprazole Metabolite 5-Hydroxy Lansoprazole Sulfide in Triple-Negative Breast Cancer by Inhibiting the Enoyl Reductase of Fatty Acid Synthase.
J Med Chem
; 65(20): 13681-13691, 2022 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36257066
16.
eIF3i regulation of protein synthesis, cell proliferation, cell cycle progression, and tumorigenesis.
Cancer Lett
; 500: 11-20, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33301799
17.
Proton pump inhibitors suppress DNA damage repair and sensitize treatment resistance in breast cancer by targeting fatty acid synthase.
Cancer Lett
; 509: 1-12, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33813001
18.
The effect of eIF3a on anthracycline-based chemotherapy resistance by regulating DSB DNA repair.
Biochem Pharmacol
; 190: 114616, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34022189
19.
Inhibiting Fatty Acid Synthase with Omeprazole to Improve Efficacy of Neoadjuvant Chemotherapy in Patients with Operable TNBC.
Clin Cancer Res
; 27(21): 5810-5817, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34400413
20.
Role of 14-3-3σ in poor prognosis and in radiation and drug resistance of human pancreatic cancers.
BMC Cancer
; 10: 598, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21040574