Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

ATF3 coordinates serine and nucleotide metabolism to drive cell cycle progression in acute myeloid leukemia.

Di Marcantonio, Daniela; Martinez, Esteban; Kanefsky, Joice S; Huhn, Jacklyn M; Gabbasov, Rashid; Gupta, Anushk; Krais, John J; Peri, Suraj; Tan, YinFei; Skorski, Tomasz; Dorrance, Adrienne; Garzon, Ramiro; Goldman, Aaron R; Tang, Hsin-Yao; Johnson, Neil; Sykes, Stephen M.

Mol Cell ; 81(13): 2752-2764.e6, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-34081901

2.

Non-Coding RNAs Are Implicit in Chronic Myeloid Leukemia Therapy Resistance.

Rudich, Alexander; Garzon, Ramiro; Dorrance, Adrienne.

Int J Mol Sci ; 23(20)2022 Oct 14.

Artigo em Inglês | MEDLINE | ID: mdl-36293127

3.

Knockout of both miR-15/16 loci induces acute myeloid leukemia.

Lovat, Francesca; Fassan, Matteo; Sacchi, Diana; Ranganathan, Parvathi; Palamarchuk, Alexey; Bill, Marius; Karunasiri, Malith; Gasparini, Pierluigi; Nigita, Giovanni; Distefano, Rosario; Veneziano, Dario; Dorrance, Adrienne M; Garzon, Ramiro; Croce, Carlo M.

Proc Natl Acad Sci U S A ; 115(51): 13069-13074, 2018 12 18.

Artigo em Inglês | MEDLINE | ID: mdl-30478046

4.

Mutations associated with a 17-gene leukemia stem cell score and the score's prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia.

Bill, Marius; Nicolet, Deedra; Kohlschmidt, Jessica; Walker, Christopher J; Mrózek, Krzysztof; Eisfeld, Ann-Kathrin; Papaioannou, Dimitrios; Rong-Mullins, Xiaoqing; Brannan, Zachary; Kolitz, Jonathan E; Powell, Bayard L; Archer, Kellie J; Dorrance, Adrienne M; Carroll, Andrew J; Stone, Richard M; Byrd, John C; Garzon, Ramiro; Bloomfield, Clara D.

Haematologica ; 105(3): 721-729, 2020 03.

Artigo em Inglês | MEDLINE | ID: mdl-31413100

5.

Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia.

Papaioannou, Dimitrios; Shen, Changxian; Nicolet, Deedra; McNeil, Betina; Bill, Marius; Karunasiri, Malith; Burke, Matthew H; Ozer, Hatice Gulcin; Yilmaz, Selen A; Zitzer, Nina; Behbehani, Gregory K; Oakes, Christopher C; Steiner, Damian J; Marcucci, Guido; Powell, Bayard L; Kolitz, Jonathan E; Carter, Thomas H; Wang, Eunice S; Mrózek, Krzysztof; Croce, Carlo M; Caligiuri, Michael A; Bloomfield, Clara D; Garzon, Ramiro; Dorrance, Adrienne M.

Proc Natl Acad Sci U S A ; 114(23): E4641-E4647, 2017 06 06.

Artigo em Inglês | MEDLINE | ID: mdl-28533390

6.

"Mast"ering drug discovery with iPSCs.

Dorrance, Adrienne.

Blood ; 137(15): 1993-1994, 2021 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-33856443

7.

The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34⁺CD123⁺ cells from acute myeloid leukemia/myelodysplastic syndrome patients and healthy donors.

Mani, Rajeswaran; Goswami, Swagata; Gopalakrishnan, Bhavani; Ramaswamy, Rahul; Wasmuth, Ronni; Tran, Minh; Mo, Xiaokui; Gordon, Amber; Bucci, Donna; Lucas, David M; Mims, Alice; Brooks, Christopher; Dorrance, Adrienne; Walker, Alison; Blum, William; Byrd, John C; Lozanski, Gerard; Vasu, Sumithira; Muthusamy, Natarajan.

Haematologica ; 103(8): 1288-1297, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29773600

8.

Targeting Wnt signaling in acute myeloid leukemia stem cells.

Pepe, Felice; Bill, Marius; Papaioannou, Dimitrios; Karunasiri, Malith; Walker, Allison; Naumann, Eric; Snyder, Katiri; Ranganathan, Parvathi; Dorrance, Adrienne; Garzon, Ramiro.

Haematologica ; 107(1): 307-311, 2022 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-34525792

9.

Targeting BRD4 in acute myeloid leukemia with partial tandem duplication of the MLL gene.

Bill, Marius; Goda, Chinmayee; Pepe, Felice; Ozer, Hatice Gulcin; McNeil, Betina; Zhang, Xiaoli; Karunasiri, Malith; Kulkarni, Rohan; Kalyan, Sonu; Papaioannou, Dimitrios; Ferenchak, Gregory; Garzon, Ramiro; Bradner, James E; Marcucci, Guido; Caligiuri, Michael A; Dorrance, Adrienne M.

Haematologica ; 106(9): 2527-2532, 2021 09 01.

Artigo em Inglês | MEDLINE | ID: mdl-33979989

10.

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

Dorrance, Adrienne M; De Vita, Serena; Radu, Maria; Reddy, Pavankumar N G; McGuinness, Meaghan K; Harris, Chad E; Mathieu, Ronald; Lane, Steven W; Kosoff, Rachelle; Milsom, Michael D; Chernoff, Jonathan; Williams, David A.

Blood ; 121(13): 2474-82, 2013 Mar 28.

Artigo em Inglês | MEDLINE | ID: mdl-23335370

11.

Eradicating acute myeloid leukemia in a Mll(PTD/wt):Flt3(ITD/wt) murine model: a path to novel therapeutic approaches for human disease.

Bernot, Kelsie M; Nemer, John S; Santhanam, Ramasamy; Liu, Shujun; Zorko, Nicholas A; Whitman, Susan P; Dickerson, Kathryn E; Zhang, Mengzi; Yang, Xiaojuan; McConnell, Kathleen K; Ahmed, Elshafa H; Muñoz, Maura R; Siebenaler, Ronald F; Marcucci, Gabriel G; Mundy-Bosse, Bethany L; Brook, Daniel L; Garman, Sabrina; Dorrance, Adrienne M; Zhang, Xiaoli; Zhang, Jianying; Lee, Robert J; Blum, William; Caligiuri, Michael A; Marcucci, Guido.

Blood ; 122(23): 3778-83, 2013 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-24085765

12.

Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia.

Hickey, Christopher J; Schwind, Sebastian; Radomska, Hanna S; Dorrance, Adrienne M; Santhanam, Ramasamy; Mishra, Anjali; Wu, Yue-Zhong; Alachkar, Houda; Maharry, Kati; Nicolet, Deedra; Mrózek, Krzysztof; Walker, Alison; Eiring, Anna M; Whitman, Susan P; Becker, Heiko; Perrotti, Danilo; Wu, Lai-Chu; Zhao, Xi; Fehniger, Todd A; Vij, Ravi; Byrd, John C; Blum, William; Lee, L James; Caligiuri, Michael A; Bloomfield, Clara D; Garzon, Ramiro; Marcucci, Guido.

Blood ; 121(1): 159-69, 2013 Jan 03.

Artigo em Inglês | MEDLINE | ID: mdl-23100311

13.

Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.

Lane, Steven W; De Vita, Serena; Alexander, Kylie A; Karaman, Ruchan; Milsom, Michael D; Dorrance, Adrienne M; Purdon, Amy; Louis, Leeann; Bouxsein, Mary L; Williams, David A.

Blood ; 119(3): 736-44, 2012 Jan 19.

Artigo em Inglês | MEDLINE | ID: mdl-22123845

14.

Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias.

Zorko, Nicholas A; Bernot, Kelsie M; Whitman, Susan P; Siebenaler, Ronald F; Ahmed, Elshafa H; Marcucci, Gabriele G; Yanes, Daniel A; McConnell, Kathleen K; Mao, Charlene; Kalu, Chidimma; Zhang, Xiaoli; Jarjoura, David; Dorrance, Adrienne M; Heerema, Nyla A; Lee, Benjamin H; Huang, Gang; Marcucci, Guido; Caligiuri, Michael A.

Blood ; 120(5): 1130-6, 2012 Aug 02.

Artigo em Inglês | MEDLINE | ID: mdl-22674806

15.

Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors.

Nieborowska-Skorska, Margaret; Kopinski, Piotr K; Ray, Regina; Hoser, Grazyna; Ngaba, Danielle; Flis, Sylwia; Cramer, Kimberly; Reddy, Mamatha M; Koptyra, Mateusz; Penserga, Tyrone; Glodkowska-Mrowka, Eliza; Bolton, Elisabeth; Holyoake, Tessa L; Eaves, Connie J; Cerny-Reiterer, Sabine; Valent, Peter; Hochhaus, Andreas; Hughes, Timothy P; van der Kuip, Heiko; Sattler, Martin; Wiktor-Jedrzejczak, Wieslaw; Richardson, Christine; Dorrance, Adrienne; Stoklosa, Tomasz; Williams, David A; Skorski, Tomasz.

Blood ; 119(18): 4253-63, 2012 May 03.

Artigo em Inglês | MEDLINE | ID: mdl-22411871

16.

Guanine nucleotide exchange factor Vav1 regulates perivascular homing and bone marrow retention of hematopoietic stem and progenitor cells.

Sanchez-Aguilera, Abel; Lee, Yun-Jung; Lo Celso, Cristina; Ferraro, Francesca; Brumme, Kristina; Mondal, Subhanjan; Kim, Chaekyun; Dorrance, Adrienne; Luo, Hongbo R; Scadden, David T; Williams, David A.

Proc Natl Acad Sci U S A ; 108(23): 9607-12, 2011 Jun 07.

Artigo em Inglês | MEDLINE | ID: mdl-21606370

17.

Epidermal growth factor-like 7 is a novel therapeutic target in mantle cell lymphoma.

Goda, Chinmayee; Kolovich, Sofia; Rudich, Alexander; Karunasiri, Malith; Kulkarni, Rohan; Rajgolikar, Girish; Neidemire-Colley, Lotus; Singh, Satishkumar; Sircar, Anuvrat; Ranganathan, Parvathi; Garzon, Ramiro; Sehgal, Lalit; Dorrance, Adrienne M.

Exp Hematol ; 123: 28-33.e3, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37209901

18.

In vivo role of Flt3 ligand and dendritic cells in NK cell homeostasis.

Guimond, Martin; Freud, Aharon G; Mao, Hsiaoyin C; Yu, Jianhua; Blaser, Bradley W; Leong, Jeffrey W; Vandeusen, Jeffrey B; Dorrance, Adrienne; Zhang, Jianying; Mackall, Crystal L; Caligiuri, Michael A.

J Immunol ; 184(6): 2769-75, 2010 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-20142363

19.

Role of endothelial cells in graft-versus-host disease.

Neidemire-Colley, Lotus; Robert, Jérémy; Ackaoui, Antoine; Dorrance, Adrienne M; Guimond, Martin; Ranganathan, Parvathi.

Front Immunol ; 13: 1033490, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36505438

20.

Corrigendum: Role of endothelial cells in graft-versus-host disease.