Detalhe da pesquisa
1.
Functional and neuropathological changes induced by injection of distinct alpha-synuclein strains: A pilot study in non-human primates.
Neurobiol Dis
; 180: 106086, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36933673
2.
Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology.
Brain
; 145(3): 1001-1017, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35285474
3.
In vivo susceptibility to energy failure parkinsonism and LRRK2 kinase activity.
Neurobiol Dis
; 162: 105579, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871735
4.
Evaluation of blood flow as a route for propagation in experimental synucleinopathy.
Neurobiol Dis
; 150: 105255, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33421564
5.
In vivo electrophysiological validation of DREADD-based modulation of pallidal neurons in the non-human primate.
Eur J Neurosci
; 53(7): 2192-2204, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32306446
6.
Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates.
Brain
; 143(5): 1462-1475, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32380543
7.
Acute Striato-Cortical Synchronization Induces Focal Motor Seizures in Primates.
Cereb Cortex
; 30(12): 6469-6480, 2020 11 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32776091
8.
Ablation of the tail of the ventral tegmental area compensates symptoms in an experimental model of Parkinson's disease.
Neurobiol Dis
; 139: 104818, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32087289
9.
Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease.
Brain
; 142(8): 2402-2416, 2019 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31243443
10.
Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration.
Hum Mol Genet
; 26(14): 2603-2615, 2017 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28520872
11.
G2019S LRRK2 mutation facilitates α-synuclein neuropathology in aged mice.
Neurobiol Dis
; 120: 21-33, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30172844
12.
Unexpected toxicity of very low dose MPTP in mice: A clue to the etiology of Parkinson's disease?
Synapse
; 70(2): 49-51, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26583879
13.
Early prenatal exposure to MPTP does not affect nigrostrial neurons in macaque monkey.
Synapse
; 70(2): 52-6, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26584009
14.
Lewy body extracts from Parkinson disease brains trigger α-synuclein pathology and neurodegeneration in mice and monkeys.
Ann Neurol
; 75(3): 351-62, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24243558
15.
Immediate-early gene expression in structures outside the basal ganglia is associated to l-DOPA-induced dyskinesia.
Neurobiol Dis
; 62: 179-92, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24103779
16.
Coordinated reset has sustained aftereffects in Parkinsonian monkeys.
Ann Neurol
; 72(5): 816-20, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-23280797
17.
Inhibition of Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) signaling in the striatum reverts motor symptoms associated with L-dopa-induced dyskinesia.
Proc Natl Acad Sci U S A
; 107(50): 21824-9, 2010 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-21115823
18.
Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain.
NPJ Parkinsons Dis
; 9(1): 135, 2023 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37726343
19.
Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia.
Ann Neurol
; 68(5): 619-28, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20882603
20.
Pilot Study Assessing the Impact of Intrathecal Administration of Variants AAV-PHP.B and AAV-PHP.eB on Brain Transduction in Adult Rhesus Macaques.
Front Bioeng Biotechnol
; 9: 762209, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34869273