Detalhe da pesquisa
1.
Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer.
Cell
; 161(7): 1539-1552, 2015 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26091037
2.
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.
Cell
; 158(3): 579-92, 2014 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-25083869
3.
Life in the fast lane: mammalian disease models in the genomics era.
Cell
; 148(6): 1099-109, 2012 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22424222
4.
Dietary fructose improves intestinal cell survival and nutrient absorption.
Nature
; 597(7875): 263-267, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34408323
5.
A rapid and scalable system for studying gene function in mice using conditional RNA interference.
Cell
; 145(1): 145-58, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21458673
6.
p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer.
Cell
; 165(6): 1546-1547, 2016 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27259155
7.
Serine Supports Epithelial and Immune Cell Function in Colitis.
Am J Pathol
; 194(6): 927-940, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38417696
8.
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets.
Proc Natl Acad Sci U S A
; 119(17): e2110557119, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35442775
9.
In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.
EMBO J
; 39(5): e102169, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31930530
10.
RB depletion is required for the continuous growth of tumors initiated by loss of RB.
PLoS Genet
; 17(12): e1009941, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34879057
11.
Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice.
J Biol Chem
; 297(1): 100815, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34023388
12.
Comprehensive microRNA analysis across genome-edited colorectal cancer organoid models reveals miR-24 as a candidate regulator of cell survival.
BMC Genomics
; 23(1): 792, 2022 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36457077
13.
GO: a functional reporter system to identify and enrich base editing activity.
Nucleic Acids Res
; 48(6): 2841-2852, 2020 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32112097
14.
Preclinical murine platform to evaluate therapeutic countermeasures against radiation-induced gastrointestinal syndrome.
Proc Natl Acad Sci U S A
; 116(41): 20672-20678, 2019 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31551264
15.
A modular and flexible ESC-based mouse model of pancreatic cancer.
Genes Dev
; 28(1): 85-97, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24395249
16.
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Nature
; 525(7570): 543-547, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26367798
17.
Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing.
Carcinogenesis
; 41(3): 334-344, 2020 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31170286
18.
Base editing the mammalian genome.
Methods
; 164-165: 100-108, 2019 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30836137
19.
Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomas.
Proc Natl Acad Sci U S A
; 113(11): 3030-5, 2016 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26929372
20.
The polarity protein Scribble regulates myelination and remyelination in the central nervous system.
PLoS Biol
; 13(3): e1002107, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25807062