Detalhe da pesquisa
1.
Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes.
Cell
; 163(4): 894-906, 2015 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26544938
2.
Clarin-2 gene supplementation durably preserves hearing in a model of progressive hearing loss.
Mol Ther
; 32(3): 800-817, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38243601
3.
Hyperacusis in the Adult Fmr1-KO Mouse Model of Fragile X Syndrome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels.
Int J Mol Sci
; 24(14)2023 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37511622
4.
Viral Transfer of Mini-Otoferlins Partially Restores the Fast Component of Exocytosis and Uncovers Ultrafast Endocytosis in Auditory Hair Cells of Otoferlin Knock-Out Mice.
J Neurosci
; 39(18): 3394-3411, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833506
5.
Local gene therapy durably restores vestibular function in a mouse model of Usher syndrome type 1G.
Proc Natl Acad Sci U S A
; 114(36): 9695-9700, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28835534
6.
Different CaV1.3 Channel Isoforms Control Distinct Components of the Synaptic Vesicle Cycle in Auditory Inner Hair Cells.
J Neurosci
; 37(11): 2960-2975, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193694
7.
Exocytotic machineries of vestibular type I and cochlear ribbon synapses display similar intrinsic otoferlin-dependent Ca2+ sensitivity but a different coupling to Ca2+ channels.
J Neurosci
; 34(33): 10853-69, 2014 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25122888
8.
Otoferlin as a multirole Ca2+ signaling protein: from inner ear synapses to cancer pathways.
Front Cell Neurosci
; 17: 1197611, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37538852
9.
Proof of concept of intracochlear drug administration by laser-assisted bioprinting in mice.
Hear Res
; 438: 108880, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37666034
10.
The temporal characteristics of Ca2+ entry through L-type and T-type Ca2+ channels shape exocytosis efficiency in chick auditory hair cells during development.
J Neurophysiol
; 108(11): 3116-23, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22972963
11.
The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses.
iScience
; 25(12): 105628, 2022 Dec 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36483015
12.
Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells.
J Neurosci
; 30(40): 13281-90, 2010 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20926654
13.
Synaptic Release Potentiation at Aging Auditory Ribbon Synapses.
Front Aging Neurosci
; 13: 756449, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34733152
14.
Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses.
J Neurosci
; 29(34): 10474-87, 2009 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19710301
15.
Purinergic signaling in cochleovestibular hair cells and afferent neurons.
Purinergic Signal
; 6(2): 201-9, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20806012
16.
Calcium- and otoferlin-dependent exocytosis by immature outer hair cells.
J Neurosci
; 28(8): 1798-803, 2008 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18287496
17.
Is otospiralin inner ear specific? Evidence for its expression in mouse brain.
Int J Dev Neurosci
; 27(1): 87-96, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18832023
18.
Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.
EMBO Mol Med
; 11(9): e10288, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31448880
19.
Expression of Rho GTPases Rho-A and Rac1 in the adult and developing gerbil cerebellum.
Int J Dev Neurosci
; 26(7): 723-32, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18682288
20.
Zinc protection against pneumolysin toxicity on rat cochlear hair cells.
Audiol Neurootol
; 13(1): 65-70, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-17890859