Detalhe da pesquisa
1.
Resistance gene-guided genome mining reveals the roseopurpurins as inhibitors of cyclin-dependent kinases.
Proc Natl Acad Sci U S A
; 120(48): e2310522120, 2023 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37983497
2.
An Enzymatic Prodrug-like Route to Thio and Selenoamides.
Angew Chem Int Ed Engl
; : e202404243, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38747847
3.
Reconstitution of polythioamide antibiotic backbone formation reveals unusual thiotemplated assembly strategy.
Proc Natl Acad Sci U S A
; 117(16): 8850-8858, 2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32265283
4.
Ribosome-independent peptide biosynthesis: the challenge of a unifying nomenclature.
Nat Prod Rep
; 39(3): 453-459, 2022 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34586117
5.
Alternative Benzoxazole Assembly Discovered in Anaerobic Bacteria Provides Access to Privileged Heterocyclic Scaffold.
Angew Chem Int Ed Engl
; 61(32): e202205409, 2022 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35656913
6.
A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria.
Angew Chem Int Ed Engl
; 61(37): e202206168, 2022 09 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35852818
7.
An Unexpected Split-Merge Pathway in the Assembly of the Symmetric Nonribosomal Peptide Antibiotic Closthioamide.
Angew Chem Int Ed Engl
; 60(8): 4104-4109, 2021 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33119936
8.
Enzyme-Primed Native Chemical Ligation Produces Autoinducing Cyclopeptides in Clostridia.
Angew Chem Int Ed Engl
; 60(19): 10670-10679, 2021 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33625794
9.
Enzymatic Carbon-Sulfur Bond Formation in Natural Product Biosynthesis.
Chem Rev
; 117(8): 5521-5577, 2017 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28418240
10.
Reconstitution of Iterative Thioamidation in Closthioamide Biosynthesis Reveals Tailoring Strategy for Nonribosomal Peptide Backbones.
Angew Chem Int Ed Engl
; 58(37): 13014-13018, 2019 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31276268
11.
Genome Editing Reveals Novel Thiotemplated Assembly of Polythioamide Antibiotics in Anaerobic Bacteria.
Angew Chem Int Ed Engl
; 57(43): 14080-14084, 2018 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30193003
12.
Enzymatic Thioamide Formation in a Bacterial Antimetabolite Pathway.
Angew Chem Int Ed Engl
; 57(36): 11574-11578, 2018 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29947149
13.
A prevalent peptide-binding domain guides ribosomal natural product biosynthesis.
Nat Chem Biol
; 11(8): 564-70, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26167873
14.
Discovery of a new ATP-binding motif involved in peptidic azoline biosynthesis.
Nat Chem Biol
; 10(10): 823-9, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25129028
15.
Identification of an Auxiliary Leader Peptide-Binding Protein Required for Azoline Formation in Ribosomal Natural Products.
J Am Chem Soc
; 137(24): 7672-7, 2015 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26024319
16.
YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations.
Nat Chem Biol
; 8(6): 569-75, 2012 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22522320
17.
Insights into the mechanism of peptide cyclodehydrations achieved through the chemoenzymatic generation of amide derivatives.
J Am Chem Soc
; 135(23): 8692-701, 2013 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23721104
18.
Selectivity, directionality, and promiscuity in peptide processing from a Bacillus sp. Al Hakam cyclodehydratase.
J Am Chem Soc
; 134(11): 5309-16, 2012 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22401305
19.
Turning the world's DNA into new medicines.
Trends Biotechnol
; 40(6): 766-767, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35232575
20.
Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis.
ACS Chem Biol
; 8(3): 473-87, 2013 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23286465