Detalhe da pesquisa
1.
Probing the Binding Mechanism of Acylated Peptides to Human Serum Albumin.
ACS Chem Biol
; 18(5): 1158-1167, 2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37145869
2.
Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (RORγt).
J Med Chem
; 64(9): 5470-5484, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33852312
3.
Discovery and characterization of a neutralizing pan-ELR+CXC chemokine monoclonal antibody.
MAbs
; 12(1): 1831880, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33183151
4.
Integration of phage and yeast display platforms: A reliable and cost effective approach for binning of peptides as displayed on-phage.
PLoS One
; 15(6): e0233961, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32479512
5.
N+1 Engineering of an Aspartate Isomerization Hotspot in the Complementarity-Determining Region of a Monoclonal Antibody.
J Pharm Sci
; 105(2): 512-518, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26869414
6.
Novel Autotaxin Inhibitors for the Treatment of Osteoarthritis Pain: Lead Optimization via Structure-Based Drug Design.
ACS Med Chem Lett
; 7(9): 857-61, 2016 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27660691
7.
A novel glucokinase activator modulates pancreatic islet and hepatocyte function.
Endocrinology
; 146(9): 3696-701, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15919746
8.
Identification of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 that are efficacious in both chemical and surgical models of osteoarthritis.
J Med Chem
; 57(24): 10476-85, 2014 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25415648
9.
Discovery of Cathepsin S Inhibitor LY3000328 for the Treatment of Abdominal Aortic Aneurysm.
ACS Med Chem Lett
; 5(10): 1138-42, 2014 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313327
10.
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 5: Combined A- and C-ring structure-activity relationship studies.
Bioorg Med Chem Lett
; 17(20): 5563-6, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17804226
11.
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 2: structure-activity relationship studies on the benzopyran scaffold.
Bioorg Med Chem Lett
; 17(13): 3570-4, 2007 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17485205
12.
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 3: synthesis of cyclopentanone and cyclohexanone intermediates for C-ring modification.
Bioorg Med Chem Lett
; 17(17): 4824-8, 2007 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17614275
13.
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: functionalization of the benzopyran A-ring.
Bioorg Med Chem Lett
; 17(18): 5082-5, 2007 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17662603