1.
J Pept Sci
; 6(1): 11-8, 2000 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10674715
RESUMO
The solid phase synthesis of a set of peptide aldehydes derived from the NS5A/NS5B junction of hepatitis C virus (HCV) viral polyprotein is demonstrated using an oxazolidine linker and the Multipin method. Deletion of the P6 and P5 residues results in a dramatic loss of inhibitory activity.