Detalhe da pesquisa
1.
Recent developments in the use of pyruvate kinase activators as a new approach for treating sickle cell disease.
Blood
; 143(10): 866-871, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38118071
2.
Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.
Proc Natl Acad Sci U S A
; 119(40): e2210779119, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36161945
3.
A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease.
Blood
; 140(19): 2053-2062, 2022 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35576529
4.
Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease.
Haematologica
; 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38450513
5.
Estimating computational limits on theoretical descriptions of biological cells.
Proc Natl Acad Sci U S A
; 118(6)2021 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495364
6.
Treatment of sickle cell disease by increasing oxygen affinity of hemoglobin.
Blood
; 138(13): 1172-1181, 2021 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34197597
7.
Psychiatric comorbidity in the Baltimore ECA follow-up study: the matrix approach.
Soc Psychiatry Psychiatr Epidemiol
; 58(1): 141-151, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-34820686
8.
Physics of virus transmission by speaking droplets.
Proc Natl Acad Sci U S A
; 117(41): 25209-25211, 2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32973098
9.
Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease.
Proc Natl Acad Sci U S A
; 117(26): 15018-15027, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32527859
10.
Association of common infections with cognitive performance in the Baltimore Epidemiologic Catchment Area study follow-up.
Alzheimers Dement
; 19(11): 4841-4851, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37027458
11.
Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model.
Blood Cells Mol Dis
; 95: 102660, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35366607
12.
From population to neuron: exploring common mediators for metabolic problems and mental illnesses.
Mol Psychiatry
; 26(8): 3931-3942, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33173197
13.
A retrospective on statistical mechanical models for hemoglobin allostery.
J Chem Phys
; 157(18): 184104, 2022 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36379793
14.
The Relationship Between Latinxs' Acculturative Experiences and Mental and Behavioral Disorder in the National Latino and Asian American Study.
Prev Sci
; 23(7): 1196-1207, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35499798
15.
MWC allosteric model explains unusual hemoglobin-oxygen binding curves from sickle cell drug binding.
Biophys J
; 120(12): 2543-2551, 2021 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33932439
16.
Impact of Conformational Substates and Energy Landscapes on Understanding Hemoglobin Kinetics and Function.
J Biol Phys
; 47(4): 337-353, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34762226
17.
Genetic propensity for risky behavior and depression and risk of lifetime suicide attempt among urban African Americans in adolescence and young adulthood.
Am J Med Genet B Neuropsychiatr Genet
; 186(8): 456-468, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34231309
18.
Hemoglobin S polymerization and sickle cell disease: A retrospective on the occasion of the 70th anniversary of Pauling's Science paper.
Am J Hematol
; 95(2): 205-211, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31763707
19.
The serotonin transporter gene polymorphism (SLC6A4) and risk for psychiatric morbidity and comorbidity in the Baltimore ECA follow-up study.
Compr Psychiatry
; 102: 152199, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32911381
20.
Kinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease.
Proc Natl Acad Sci U S A
; 114(5): E689-E696, 2017 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28096387