Detalhe da pesquisa
1.
Long-term reductions in disease impact in patients with chronic migraine following preventive treatment with eptinezumab.
BMC Neurol
; 22(1): 251, 2022 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35804294
2.
An ethnographic study of the effects of cognitive symptoms in patients with major depressive disorder: the IMPACT study.
BMC Psychiatry
; 17(1): 370, 2017 11 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29157207
3.
GABA site agonist gaboxadol induces addiction-predicting persistent changes in ventral tegmental area dopamine neurons but is not rewarding in mice or baboons.
J Neurosci
; 32(15): 5310-20, 2012 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22496576
4.
The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT(3) receptor antagonism.
Int J Neuropsychopharmacol
; 16(5): 1115-27, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23089374
5.
Multi-omics data integration methods and their applications in psychiatric disorders.
Eur Neuropsychopharmacol
; 69: 26-46, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706689
6.
Combining escitalopram with gaboxadol provides no additional benefit in the treatment of patients with severe major depressive disorder.
Int J Neuropsychopharmacol
; 15(6): 715-25, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22008735
7.
Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol.
J Pharmacol Exp Ther
; 338(1): 214-9, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21450931
8.
Patient Expectations and Experiences of Antidepressant Therapy for Major Depressive Disorder: A Qualitative Study.
Neuropsychiatr Dis Treat
; 17: 2995-3006, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34588779
9.
Distinct activities of GABA agonists at synaptic- and extrasynaptic-type GABAA receptors.
J Physiol
; 588(Pt 8): 1251-68, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20176630
10.
Triton X-100 inhibits agonist-induced currents and suppresses benzodiazepine modulation of GABA(A) receptors in Xenopus oocytes.
Biochim Biophys Acta
; 1788(5): 1073-80, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19366585
11.
Alterations in cyclic alternating pattern associated with phase advanced sleep are differentially modulated by gaboxadol and zolpidem.
Sleep
; 33(11): 1562-70, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21102998
12.
Gaboxadol -- a different hypnotic profile with no tolerance to sleep EEG and sedative effects after repeated daily dosing.
Pharmacol Biochem Behav
; 90(1): 113-22, 2008 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-18304623
13.
The multimodal antidepressant vortioxetine may facilitate pyramidal cell firing by inhibition of 5-HT3 receptor expressing interneurons: An in vitro study in rat hippocampus slices.
Brain Res
; 1689: 1-11, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29274875
14.
Treating insomnia: Current and investigational pharmacological approaches.
Pharmacol Ther
; 112(3): 612-29, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16876255
15.
4-aryl-5-(4-piperidyl)-3-isoxazolol GABAA antagonists: synthesis, pharmacology, and structure-activity relationships.
J Med Chem
; 50(8): 1988-92, 2007 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-17375905
16.
5-Substituted imidazole-4-acetic acid analogues: synthesis, modeling, and pharmacological characterization of a series of novel gamma-aminobutyric acid(C) receptor agonists.
J Med Chem
; 50(17): 4147-61, 2007 Aug 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-17655213
17.
A tetrazolyl-substituted subtype-selective AMPA receptor agonist.
J Med Chem
; 50(10): 2408-14, 2007 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-17455929
18.
Lack of generalisation between the GABAA receptor agonist, gaboxadol, and allosteric modulators of the benzodiazepine binding site in the rat drug discrimination procedure.
Psychopharmacology (Berl)
; 193(1): 151-7, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17361395
19.
Plasma and CNS concentrations of Gaboxadol in rats following subcutaneous administration.
Eur J Pharmacol
; 562(1-2): 47-52, 2007 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-17362924
20.
Gaboxadol--a new awakening in sleep.
Curr Opin Pharmacol
; 6(1): 30-6, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16368265