Detalhe da pesquisa
1.
The discovery and preclinical characterization of 6-chloro-N-(2-(4,4-difluoropiperidin-1-yl)-2-(2-(trifluoromethyl)pyrimidin-5-yl)ethyl)quinoline-5-carboxamide based P2X7 antagonists.
Bioorg Med Chem Lett
; 26(19): 4781-4784, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27595421
2.
Discovery of a novel series of selective HCN1 blockers.
Bioorg Med Chem Lett
; 21(18): 5197-201, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21824780
3.
Functional α6ß4 acetylcholine receptor expression enables pharmacological testing of nicotinic agonists with analgesic properties.
J Clin Invest
; 130(11): 6158-6170, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33074244
4.
Selective inhibition of peripheral cathepsin S reverses tactile allodynia following peripheral nerve injury in mouse.
Eur J Pharmacol
; 880: 173171, 2020 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32437743
5.
Morphology and axonal arborization of rat spinal inner lamina II neurons hyperpolarized by mu-opioid-selective agonists.
J Comp Neurol
; 458(3): 240-56, 2003 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-12619079
6.
Hyperpolarization of substantia gelatinosa neurons evoked by mu-, kappa-, delta 1-, and delta 2-selective opioids.
J Pain
; 3(2): 115-25, 2002 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-14622798
7.
Spared nerve injury model of neuropathic pain in the mouse: a behavioral and anatomic analysis.
J Pain
; 4(8): 465-70, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14622667
8.
Rodent models of persistent pain in drug discovery and development.
Curr Pharm Biotechnol
; 12(10): 1590-5, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21466453
9.
Characterization of 2-(2,6-dichloro-benzyl)-thiazolo[5,4-d]pyrimidin-7-yl]-(4-trifluoromethyl-phenyl)-amine (JNJ-39729209) as a novel TRPV1 antagonist.
Eur J Pharmacol
; 663(1-3): 40-50, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21575625
10.
Recent advances in the biology and medicinal chemistry of TRPA1.
Future Med Chem
; 2(5): 843-58, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21426205