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1.
Nutr Diabetes ; 10(1): 34, 2020 Sep 23.
Artigo em Inglês | MEDLINE | ID: mdl-32968050

RESUMO

Following publication, the authors asked to add the following institution to the affiliations of author Madoka Matsushita: Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine Both the PDF and HTML versions of the Article have been updated accordingly.

2.
Nutr Diabetes ; 10(1): 33, 2020 08 29.
Artigo em Inglês | MEDLINE | ID: mdl-32862192

RESUMO

BACKGROUND: The aim of this study was to determine the effectiveness of the Smart Life Stay (SLS) program, which is an experience-oriented stayover program, in combination with health tourism and mandatory health guidance on glucose metabolism after 2 years. METHODS: The participants of the SLS program (n = 792) were recruited from a database of 23 medical insurers. They underwent a mandatory health examination termed Specific Health Checkups in 2014. The participants were included if they had diabetes or were at a high risk of diabetes and if they satisfied the following inclusion criteria: (1) body mass index (BMI; kg/m2) > 25, or (2) waist circumference (WC; cm) > 85 for men and > 90 for women, or (3) hemoglobin A1c (HbA1c; %) > 5.6, or (4) fasting plasma glucose (FPG; mg/dl) > 100. Individuals who corresponded to one or more items were included as study participants. The control subjects (n = 3645) were nonparticipants of the program who were selected from the database and met the inclusion criteria. The lifestyle changes and changes in mean BMI, WC, FPG, and HbA1c in both groups from baseline to 2-year follow-up were compared by inverse probability weighting of a propensity score. RESULTS: The percentage of people who exercised regularly increased significantly in the SLS group compared with the control group. In the SLS group, BW, BMI, and WC significantly decreased by 1.75 kg, 0.60 kg/m2, and 1.45 cm, respectively, whereas in the control group, WC, FPG, and HbA1c increased significantly by 0.38 cm, 3.37 mg/dl, and 0.12%, respectively. The comparison between groups revealed that the BW, BMI, WC, FPG, and HbA1c improved significantly in the SLS group. CONCLUSIONS: The SLS program is suggested to help improve glucose metabolism. This program could be a feasible option as a lifestyle intervention program for diabetes.


Assuntos
Diabetes Mellitus Tipo 2/terapia , Promoção da Saúde/métodos , Estilo de Vida , Turismo , Glicemia/análise , Índice de Massa Corporal , Aconselhamento , Diabetes Mellitus Tipo 2/prevenção & controle , Exercício Físico , Jejum/sangue , Feminino , Seguimentos , Hemoglobinas Glicadas/análise , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Risco , Circunferência da Cintura
3.
Early Hum Dev ; 69(1-2): 35-46, 2002 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-12324181

RESUMO

The objective of this study is to determine the difference of the flow velocities of left and right cerebral arteries. We also studied the effect of head position to the cerebral arterial flow velocities. Eligible for inclusion in this study were 60 neonatal infants whose gestational age was 33.1+/-3.5 weeks and whose birth weight was 1793+/-613 g. The ultrasonographic examinations were performed in the first and second weeks after birth. In an axial scan through a temporal window, the Doppler sample volume was positioned at the center of the M1 portion of the middle cerebral artery and the flow velocity curve was detected. No statistical difference was seen in the flow velocities between the left and right middle cerebral arteries. However, the flow velocities in the upper side were significantly higher than those in the lower side. RI in the upper side was significantly smaller than that in the lower one. This change of flow velocities stabilized in 5 min after the head was turned upside down. The effect of head positioning to the intracranial blood flow must be considered when cerebral ultrasonography of neonates is performed.


Assuntos
Artérias Cerebrais/fisiologia , Córtex Cerebral/irrigação sanguínea , Postura/fisiologia , Velocidade do Fluxo Sanguíneo/fisiologia , Artérias Cerebrais/diagnóstico por imagem , Córtex Cerebral/diagnóstico por imagem , Movimentos da Cabeça/fisiologia , Humanos , Recém-Nascido , Fluxo Sanguíneo Regional/fisiologia , Ultrassonografia Doppler
4.
Early Hum Dev ; 68(1): 55-64, 2002 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12191529

RESUMO

The objective of this study is to determine the causes of asymmetry of the lateral ventricles in neonates. We also studied the effect of head position and the relationship of body weight at birth in regard to lateral ventricular size. Eligible for inclusion in this study were 60 neonatal infants whose gestational age was 33.1+/-3.5 weeks and whose birth weight was 1793+/-613 g. Ultrasonographic examinations were performed at the first and the second weeks after birth. In parasagittal and coronal scans through the posterior horn of the lateral ventricle, the lateral ventricle was traced and its area was measured. We found no significant variation of ventricular size in relation to body weight at birth. The left ventricular size was larger than the right one. The difference of the left and right ventricular sizes was partially effected by head position. The ratio of left to right lateral ventricular sizes showed a very wide distribution. We considered that ventricular asymmetry is not pathological, but due to individual differences.


Assuntos
Ventrículos Cerebrais/anatomia & histologia , Envelhecimento , Peso ao Nascer , Ventrículos Cerebrais/diagnóstico por imagem , Lateralidade Funcional , Idade Gestacional , Humanos , Recém-Nascido , Recém-Nascido Prematuro , Terapia Intensiva Neonatal , Supinação , Ultrassonografia
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