Detalhe da pesquisa
1.
FinnGen provides genetic insights from a well-phenotyped isolated population.
Nature
; 613(7944): 508-518, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36653562
2.
Effect of case and control definitions on genome-wide association study (GWAS) findings.
Genet Epidemiol
; 47(5): 394-406, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37021827
3.
Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.
Nature
; 615(7952): E19, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36829046
4.
Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes.
Hum Mol Genet
; 27(15): 2762-2772, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29771307
5.
Characterization of ADME gene variation in 21 populations by exome sequencing.
Pharmacogenet Genomics
; 27(3): 89-100, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27984508
6.
The benefits of using genetic information to design prevention trials.
Am J Hum Genet
; 92(4): 547-57, 2013 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-23541341
7.
The influence of genomic context on mutation patterns in the human genome inferred from rare variants.
Genome Res
; 23(12): 1974-84, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23990608
8.
Comparing variant calling algorithms for target-exon sequencing in a large sample.
BMC Bioinformatics
; 16: 75, 2015 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25884587
9.
Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe.
Hum Mutat
; 33(7): 1087-98, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22415848
10.
Integration of Real-World Data and Genetics to Support Target Identification and Validation.
Clin Pharmacol Ther
; 111(1): 63-76, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34818443
11.
The Population Reference Sample, POPRES: a resource for population, disease, and pharmacological genetics research.
Am J Hum Genet
; 83(3): 347-58, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18760391
12.
Meta-Analysis of 26 638 Individuals Identifies Two Genetic Loci Associated With Left Ventricular Ejection Fraction.
Circ Genom Precis Med
; 13(4): e002804, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32605384
13.
Comparison of association methods for dense marker data.
Genet Epidemiol
; 32(8): 791-9, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18551558
14.
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease.
Arch Neurol
; 65(1): 45-53, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17998437
15.
Use of whole-genome association scans in disease gene identification, drug discovery and development.
IDrugs
; 10(11): 797-804, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17968762
16.
Phenome-wide association study using research participants' self-reported data provides insight into the Th17 and IL-17 pathway.
PLoS One
; 12(11): e0186405, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29091937
17.
Genome-wide and fine-mapping linkage studies of type 2 diabetes and glucose traits in the Old Order Amish: evidence for a new diabetes locus on chromosome 14q11 and confirmation of a locus on chromosome 1q21-q24.
Diabetes
; 52(2): 550-7, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12540634
18.
Effect of two- and three-locus linkage disequilibrium on the power to detect marker/phenotype associations.
Genetics
; 168(2): 1029-40, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15514073
19.
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Nat Commun
; 6: 5897, 2015 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631608
20.
Analysis of rare variant population structure in Europeans explains differential stratification of gene-based tests.
Eur J Hum Genet
; 22(9): 1137-44, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24398795