Detalhe da pesquisa
1.
DSM265 at 400 Milligrams Clears Asexual Stage Parasites but Not Mature Gametocytes from the Blood of Healthy Subjects Experimentally Infected with Plasmodium falciparum.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858218
2.
A Single-Dose Combination Study with the Experimental Antimalarials Artefenomel and DSM265 To Determine Safety and Antimalarial Activity against Blood-Stage Plasmodium falciparum in Healthy Volunteers.
Antimicrob Agents Chemother
; 64(1)2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31685476
3.
Piperaquine Monotherapy of Drug-Susceptible Plasmodium falciparum Infection Results in Rapid Clearance of Parasitemia but Is Followed by the Appearance of Gametocytemia.
J Infect Dis
; 214(1): 105-13, 2016 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27056954
4.
Linking Murine and Human Plasmodium falciparum Challenge Models in a Translational Path for Antimalarial Drug Development.
Antimicrob Agents Chemother
; 60(6): 3669-75, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27044554
5.
Experimentally induced blood-stage Plasmodium vivax infection in healthy volunteers.
J Infect Dis
; 208(10): 1688-94, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23908484
6.
Concomitant or sequential administration of live attenuated Japanese encephalitis chimeric virus vaccine and yellow fever 17D vaccine: randomized double-blind phase II evaluation of safety and immunogenicity.
Hum Vaccin
; 6(11): 906-14, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20864814
7.
A Plasmodium vivax experimental human infection model for evaluating efficacy of interventions.
J Clin Invest
; 130(6): 2920-2927, 2020 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32045385
8.
Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study.
Lancet Infect Dis
; 20(4): 445-454, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32027842
9.
Phase I trial of a CD8+ T-cell peptide epitope-based vaccine for infectious mononucleosis.
J Virol
; 82(3): 1448-57, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18032491
10.
Qualitative study investigating the underlying motivations of healthy participants in phase I clinical trials.
BMJ Open
; 9(1): e024224, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30647042
11.
Evaluation of safety and immunogenicity of a group A streptococcus vaccine candidate (MJ8VAX) in a randomized clinical trial.
PLoS One
; 13(7): e0198658, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29965967
12.
A controlled human malaria infection model enabling evaluation of transmission-blocking interventions.
J Clin Invest
; 128(4): 1551-1562, 2018 04 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29389671
13.
Plasma Epstein-Barr virus (EBV) DNA is a biomarker for EBV-positive Hodgkin's lymphoma.
Clin Cancer Res
; 12(2): 460-4, 2006 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16428487
14.
Re-assessing the vertical distribution of testate amoeba communities in surface peats: Implications for palaeohydrological studies.
Eur J Protistol
; 60: 13-27, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28688372
15.
Safety, acceptability and tolerability of uncoated and excipient-coated high density silicon micro-projection array patches in human subjects.
Vaccine
; 35(48 Pt B): 6676-6684, 2017 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29074201
16.
Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study.
Lancet Infect Dis
; 17(6): 626-635, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28363636
17.
Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and Its Potential as a Model to Evaluate Malaria Transmission.
PLoS Negl Trop Dis
; 10(12): e0005139, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27930652
18.
Reconstitution of the latent T-lymphocyte response to Epstein-Barr virus is coincident with long-term recovery from posttransplant lymphoma after adoptive immunotherapy.
Transplantation
; 75(9): 1556-60, 2003 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12792514
19.
Fasting increases serum bilirubin levels in clinically normal, healthy males but not females: a retrospective study from phase I clinical trial participants.
J Clin Pathol
; 67(6): 529-34, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24596139
20.
A pilot randomised trial of induced blood-stage Plasmodium falciparum infections in healthy volunteers for testing efficacy of new antimalarial drugs.
PLoS One
; 6(8): e21914, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21887214