Detalhe da pesquisa
1.
A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer.
Mol Cancer
; 22(1): 89, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37248468
2.
Investigating 3R In Vivo Approaches for Bio-Distribution and Efficacy Evaluation of Nucleic Acid Nanocarriers: Studies on Peptide-Mimicking Ionizable Lipid.
Small
; 18(18): e2107768, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35355412
3.
Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity.
Int J Mol Sci
; 23(14)2022 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35886887
4.
Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.
Int J Mol Sci
; 23(1)2021 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008795
5.
Studies on the Mechanisms of Anti-Inflammatory Activity of Heparin- and Hyaluronan-Containing Multilayer Coatings-Targeting NF-κB Signalling Pathway.
Int J Mol Sci
; 21(10)2020 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32466274
6.
Screening for Selective Protein Inhibitors by Using the IANUS Peptide Array.
Chembiochem
; 19(8): 789-792, 2018 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29411932
7.
Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II.
Bioorg Med Chem
; 26(14): 4014-4024, 2018 08 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29941193
8.
Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases.
Molecules
; 22(12)2017 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29168755
9.
Thioxylated cyclosporin A for studying protein-drug interactions.
Bioorg Med Chem Lett
; 26(23): 5754-5756, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27815116
10.
Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum.
EMBO J
; 30(1): 17-31, 2011 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-21102557
11.
Identification of peptidic substrates for the human kinase Myt1 using peptide microarrays.
Bioorg Med Chem
; 23(15): 4936-4942, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26059593
12.
The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6'-amino-6'-deoxy-α-d-glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase.
J Enzyme Inhib Med Chem
; 30(3): 514-7, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24939100
13.
Application of docking and QM/MM-GBSA rescoring to screen for novel Myt1 kinase inhibitors.
J Chem Inf Model
; 54(3): 881-93, 2014 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24490903
14.
Synthesis and inâ vitro Metabolic Stability of Sterically Shielded Antimycobacterial Phenylalanine Amides.
ChemMedChem
; 19(6): e202300593, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38329388
15.
Design, synthesis, and biological characterization of proteolysis targeting chimera (PROTACs) for the ataxia telangiectasia and RAD3-related (ATR) kinase.
Eur J Med Chem
; 267: 116167, 2024 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38308949
16.
In vitro and in silico studies on substrate recognition and acceptance of human PKMYT1, a Cdk1 inhibitory kinase.
Bioorg Med Chem Lett
; 22(2): 1219-23, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22189141
17.
Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties.
J Med Chem
; 65(24): 16313-16337, 2022 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36449385
18.
Identification of histone deacetylase 10 (HDAC10) inhibitors that modulate autophagy in transformed cells.
Eur J Med Chem
; 234: 114272, 2022 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35306288
19.
The novel calcineurin inhibitor CN585 has potent immunosuppressive properties in stimulated human T cells.
J Biol Chem
; 285(3): 1888-98, 2010 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19923214
20.
Augmented photoswitching modulates immune signaling.
Nat Chem Biol
; 5(10): 724-6, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19734911