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1.
Sci Data ; 8(1): 48, 2021 02 05.
Artigo em Inglês | MEDLINE | ID: mdl-33547309

RESUMO

Parkinson's disease (PD) is a neurodegenerative disorder associated with motor and non-motor symptoms. Current treatments primarily focus on managing motor symptom severity such as tremor, bradykinesia, and rigidity. However, as the disease progresses, treatment side-effects can emerge such as on/off periods and dyskinesia. The objective of the Levodopa Response Study was to identify whether wearable sensor data can be used to objectively quantify symptom severity in individuals with PD exhibiting motor fluctuations. Thirty-one subjects with PD were recruited from 2 sites to participate in a 4-day study. Data was collected using 2 wrist-worn accelerometers and a waist-worn smartphone. During Days 1 and 4, a portion of the data was collected in the laboratory while subjects performed a battery of motor tasks as clinicians rated symptom severity. The remaining of the recordings were performed in the home and community settings. To our knowledge, this is the first dataset collected using wearable accelerometers with specific focus on individuals with PD experiencing motor fluctuations that is made available via an open data repository.


Assuntos
Acelerometria/métodos , Doença de Parkinson/diagnóstico , Dispositivos Eletrônicos Vestíveis , Humanos , Núcleos Parabraquiais , Doença de Parkinson/fisiopatologia , Smartphone , Punho
2.
Sci Data ; 8(1): 47, 2021 02 05.
Artigo em Inglês | MEDLINE | ID: mdl-33547317

RESUMO

Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms. Dyskinesia and motor fluctuations are complications of PD medications. An objective measure of on/off time with/without dyskinesia has been sought for some time because it would facilitate the titration of medications. The objective of the dataset herein presented is to assess if wearable sensor data can be used to generate accurate estimates of limb-specific symptom severity. Nineteen subjects with PD experiencing motor fluctuations were asked to wear a total of five wearable sensors on both forearms and shanks, as well as on the lower back. Accelerometer data was collected for four days, including two laboratory visits lasting 3 to 4 hours each while the remainder of the time was spent at home and in the community. During the laboratory visits, subjects performed a battery of motor tasks while clinicians rated limb-specific symptom severity. At home, subjects were instructed to use a smartphone app that guided the periodic performance of a set of motor tasks.


Assuntos
Acelerometria/instrumentação , Monitorização Ambulatorial , Doença de Parkinson/diagnóstico , Dispositivos Eletrônicos Vestíveis , Antebraço , Humanos , Perna (Membro) , Aplicativos Móveis , Doença de Parkinson/fisiopatologia , Smartphone , Tronco
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