RESUMO
OBJECTIVE: To determine the efficacy of the 585-nm flashlamp-pumped pulsed-dye laser and silicone gel sheeting in the treatment of hypertrophic scars in lighter- and darker-skinned patients. DESIGN: Prospective, single-blind, randomized, internally controlled, comparison investigation. SETTING: Large academic dermatology department. PATIENTS: Twenty patients with hypertrophic scars (19 completed the laser treatments and 18 completed the silicone gel sheeting treatments). MAIN OUTCOME MEASURES: Clinical measurements included hypertrophic scar blood flow, elasticity, and volume. Patients' subjective complaints of pruritus, pain, and burning were also monitored. Histological assessment of fibrosis, number of telangiectasias, and number of mast cells was performed. Statistically significant improvements in clinical measurements and patients' subjective complaints determined treatment success. RESULTS: Mean scar duration was 32 months (range, 4 months to 20 years). There was an overall reduction in blood flow, volume, and pruritus over time (P = .001, .02, and .005, respectively). However, no differences were detected among treatment and control groups. There was no reduction in pain or burning (0-40 weeks), elasticity (8-40 weeks), or fibrosis (0-40 weeks, n = 5 biopsies) in the treated or control sections of the scars. Unlike in a previous study, the number of mast cells in the scars was similar to the number of mast cells in healthy skin. CONCLUSION: Clinical results demonstrate that the improvements in scar sections treated with silicone gel sheeting and pulsed-dye laser were no different than in control sections.
Assuntos
Cicatriz Hipertrófica/terapia , Terapia a Laser , Géis de Silicone , Adulto , Idoso , Idoso de 80 Anos ou mais , Cicatriz Hipertrófica/patologia , Corantes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Método Simples-CegoRESUMO
A 26-yr-old AC-130 gunner developed unilateral temporomandibular joint (TMJ) pain while flying a combat support mission. A diagnosis of decompression sickness (DCS) was made based on his symptoms and risk factors that included prolonged exposure to high altitude (60 to 90 min at 18,000 ft), cold temperature (-11 degrees C), and increased inflight activity. His symptoms resolved with 100% oxygen and he was returned to flying status after 72 h. Altitude related DCS is an unusual occurrence and this is the first reported case of inflight DCS affecting the temporomandibular joint.
Assuntos
Doença da Descompressão/complicações , Transtornos da Articulação Temporomandibular/etiologia , Adulto , Medicina Aeroespacial , Aeronaves , Altitude , Humanos , Masculino , Militares , Oxigênio/uso terapêutico , Dor/etiologia , Manejo da Dor , Transtornos da Articulação Temporomandibular/terapiaRESUMO
Erythema nodosum is an uncommon skin eruption frequently associated with underlying infections, systemic diseases, or drug toxicity. We report the case of a 27-year-old aviator with three occurrences of erythema nodosum attributed to streptococcal pharyngitis. We review the causes of erythema nodosum to emphasize the importance of a thorough investigation to rule out serious underlying disease prior to returning an aviator to flight status.