Detalhe da pesquisa
1.
LRRK2 suppresses lysosome degradative activity in macrophages and microglia through MiT-TFE transcription factor inhibition.
Proc Natl Acad Sci U S A
; 120(31): e2303789120, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37487100
2.
Cab45 deficiency leads to the mistargeting of progranulin and prosaposin and aberrant lysosomal positioning.
Traffic
; 24(1): 4-19, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36398980
3.
Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution.
Cell Mol Life Sci
; 81(1): 29, 2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38212474
4.
Dynamin, a membrane-remodelling GTPase.
Nat Rev Mol Cell Biol
; 13(2): 75-88, 2012 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22233676
5.
Receptor-like role for PQLC2 amino acid transporter in the lysosomal sensing of cationic amino acids.
Proc Natl Acad Sci U S A
; 118(8)2021 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33597295
6.
PLD3 is a neuronal lysosomal phospholipase D associated with ß-amyloid plaques and cognitive function in Alzheimer's disease.
PLoS Genet
; 17(4): e1009406, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33830999
7.
The complex relationship between TFEB transcription factor phosphorylation and subcellular localization.
EMBO J
; 37(11)2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29764979
8.
Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay.
Proc Natl Acad Sci U S A
; 115(12): E2849-E2858, 2018 03 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29511098
9.
C9orf72: At the intersection of lysosome cell biology and neurodegenerative disease.
Traffic
; 18(5): 267-276, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28266105
10.
Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma.
Blood
; 129(13): 1768-1778, 2017 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28104689
11.
Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes.
Proc Natl Acad Sci U S A
; 112(14): 4423-8, 2015 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25831514
12.
Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer's disease amyloid plaques.
Proc Natl Acad Sci U S A
; 112(28): E3699-708, 2015 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26124111
13.
Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis.
Development
; 141(7): 1465-72, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24598168
14.
Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitors.
J Cell Sci
; 126(Pt 22): 5305-12, 2013 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24046449
15.
Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane.
Proc Natl Acad Sci U S A
; 109(12): 4419-24, 2012 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22371560
16.
Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses.
Proc Natl Acad Sci U S A
; 109(8): E515-23, 2012 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22308498
17.
Differential curvature sensing and generating activities of dynamin isoforms provide opportunities for tissue-specific regulation.
Proc Natl Acad Sci U S A
; 108(26): E234-42, 2011 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21670293
18.
Lysosomal TBK1 Responds to Amino Acid Availability to Relieve Rab7-Dependent mTORC1 Inhibition.
bioRxiv
; 2023 Dec 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168426
19.
A kinesin-1 adaptor complex controls bimodal slow axonal transport of spectrin in Caenorhabditis elegans.
Dev Cell
; 58(19): 1847-1863.e12, 2023 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751746
20.
Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo.
J Cell Biol
; 221(2)2022 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34919127