Antibacterial Properties of Nanoparticles in Dental Restorative Materials. A Systematic Review and Meta-Analysis.

Background and Objectives: Nanotechnology has become a significant area of research focused mainly on increasing the antibacterial and mechanical properties of dental materials. The aim of the present systematic review and meta-analysis was to examine and quantitatively analyze the current evidence for the addition of different nanoparticles into dental restorative materials, to determine whether their incorporation increases the antibacterial/antimicrobial properties of the materials. Materials and Methods: A literature search was performed in the Pubmed, Scopus, and Embase databases, up to December 2018, following PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines for systematic reviews and meta-analyses. Results: A total of 624 papers were identified in the initial search. After screening the texts and applying inclusion criteria, only 11 of these were selected for quantitative analysis. The incorporation of nanoparticles led to a significant increase (p-value <0.01) in the antibacterial capacity of all the dental materials synthesized in comparison with control materials. Conclusions: The incorporation of nanoparticles into dental restorative materials was a favorable option; the antibacterial activity of nanoparticle-modified dental materials was significantly higher compared with the original unmodified materials, TiO2 nanoparticles providing the greatest benefits. However, the high heterogeneity among the articles reviewed points to the need for further research and the application of standardized research protocols.

Generation of programmable 3D optical vortex structures through devil's vortex-lens arrays.

Different spatial distributions of optical vortices have been generated and characterized by implementing arrays of devil's vortex lenses in a reconfigurable spatial light modulator. A simple design procedure assigns the preferred position and topological charge value to each vortex in the structure, tuning the desired angular momentum. Distributions with charges and momenta of the opposite sign have been experimentally demonstrated. The angular velocity exhibited by the phase distribution around the focal plane has been visualized, showing an excellent agreement with the simulations. The practical limits of the method, with interest for applications involving particle transfer and manipulation, have been evaluated.

Single-pixel polarimetric imaging.

We present an optical system that performs Stokes polarimetric imaging with a single-pixel detector. This fact is possible by applying the theory of compressive sampling to the data acquired by a commercial polarimeter without spatial resolution. The measurement process is governed by a spatial light modulator, which sequentially generates a set of preprogrammed light intensity patterns. Experimental results are presented and discussed for an object that provides an inhomogeneous polarization distribution.

Fabrication by Laser Irradiation in a Continuous Flow Jet of Carbon Quantum Dots for Fluorescence Imaging.

Fluorescent carbon quantum dots (CQDs) are synthesized by laser irradiation of carbon glassy particles suspended in polyethylene glycol 200 by two methods, a batch and a flow jet configuration. The flow jet configuration is carried out by the simple combination of common laboratory objects to construct a home-made passage reactor of continuous flow. Despite the simplicity of the system, the laser energy is better harvested by the carbon microparticles, improving the fabrication efficiency a 15% and enhancing the fluorescence of CQDs by an order of magnitude in comparison with the conventional batch. The flow jet-synthesized CQDs have a mean size of 3 nm and are used for fluorescent imaging of transparent healthy and cancer epithelial human cells. Complete internalization is observed with a short incubation time of 10 min without using any extra additive or processing of the cell culture. The CQDs are well fixed in the organelles of the cell even after its death; hence, this is a simple manner to keep the cell information for prolonged periods of time. Moreover, the integrated photostability of the CQDs internalized in in vitro cells is measured and it remains almost constant during at least 2 h, revealing their outstanding performance as fluorescent labels.

On-axis diffraction of an ultrashort light pulse by circularly symmetric hard apertures.

The analytical solution of the Rayleigh-Sommerfeld on-axis diffraction integral for an ultrashort light pulse diffracted by circularly symmetric hard apertures is derived. The particular case of a circular aperture is treated in detail. The time changes of the instantaneous intensity along the axial direction are predicted. An analysis of the standard deviation width shows a pulse broadening about the axial positions where the instantaneous intensity reaches a zero value. We show that the temporal shape of the instantaneous intensity depends on the number of oscillation cycles at the central frequency of the real electric field.

Dispersion-compensated beam-splitting of femtosecond light pulses: Wave optics analysis.

Recently, using parageometrical optics concepts, a hybrid, diffractive-refractive, lens triplet has been suggested to significantly improve the spatiotemporal resolution of light spots in multifocal processing with femtosecond laser pulses. Here, we carry out a rigorous wave-optics analysis, including the spatiotemporal nature of the wave equation, to elucidate both the spatial extent of the diffractive spots and the temporal duration of the pulse at the output plane. Specifically, we show nearly transform-limited behavior of diffraction maxima. Moreover, the temporal broadening of the pulse is related to the group velocity dispersion, which can be pre-compensated for in practical applications. Finally, some numerical simulations of the spatiotemporal wave field at the output plane in a realistic case are provided.

Millimeter-wave and microwave signal generation by low-bandwidth electro-optic phase modulation.

We propose, analyze and numerically illustrate a photonic-based technique for waveform generation of electrical signals approaching the 50 GHz bandwidth with time apertures as large as a few nanoseconds, by low-frequency, up to 2 GHz, electro-optic phase modulation of time-stretched optical pulses. Synthesis of the electrical waveform relies on phase-to-amplitude conversion of the modulated signal by a group delay dispersion circuit designed to behave as a transversal filter with N taps. Although arbitrary waveform generation capabilities are limited, a wide variety of user-defined signals are numerically demonstrated by appropriately designing the low-frequency signal driving the electro-optical modulator. Frequency upshifting is controlled by the chirp of the stretched pulse which provides an additional degree of freedom. Finally, optical-to-electrical conversion allows for the user-defined electrical waveform. Simulations are given for square waveform generation demonstrating the high resolution and wide-band capabilities of the technique.

Optical filters with fractal transmission spectra based on diffractive optics.

The duality between the axial irradiance distribution originated by any circularly symmetric diffracting aperture under monochromatic illumination and its diffracted spectral intensity at a fixed on-axis point under broadband illumination is highlighted and experimentally investigated. Two applications are derived from this basic result. On the one hand, we suggest the use of a broadband source and a spectrometer for a single-shot measurement of the axial response of pupil filters. Second, we implement a spectral filter having a transmission spectrum with a fractal structure of frequencies. Experimental results and potential applications in synthetic spectra designs are provided.

Fractal generalized zone plates.

The construction of fractal generalized zone plates from a set of periodic diffractive optical elements with circular symmetry is proposed. This allows us, for instance, to increase the number of foci of a conventional fractal zone plate while keeping the self-similarity property within the axial irradiance. The focusing properties of these fractal diffractive optical elements for points not only along but also in the close vicinity of the optical axis are investigated. In both cases analytical expressions for the irradiance are derived. Numerical simulations of the energetic efficiency of fractal generalized zone plates under plane wave illumination are carried out. In addition, some effects on the axial irradiance caused by variations in the area of their transparent rings are shown.