Detalhe da pesquisa
1.
Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension.
Circulation
; 2024 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38695173
2.
Identification of covalent fragment inhibitors for Plasmodium falciparum UCHL3 with anti-malarial efficacy.
Bioorg Med Chem Lett
; 94: 129458, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37634761
3.
Inhibition of pathogenic bacterial carbonic anhydrases by monothiocarbamates.
J Enzyme Inhib Med Chem
; 38(1): 2284119, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37994421
4.
Coumarins effectively inhibit bacterial α-carbonic anhydrases.
J Enzyme Inhib Med Chem
; 37(1): 333-338, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34979838
5.
Inhibition studies of bacterial α-carbonic anhydrases with phenols.
J Enzyme Inhib Med Chem
; 37(1): 666-671, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35139743
6.
Dithiocarbamates effectively inhibit the α-carbonic anhydrase from Neisseria gonorrhoeae.
J Enzyme Inhib Med Chem
; 37(1): 1-8, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34894954
7.
Structure-activity relationship studies for inhibitors for vancomycin-resistant Enterococcus and human carbonic anhydrases.
J Enzyme Inhib Med Chem
; 37(1): 1838-1844, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-35758212
8.
Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae.
J Enzyme Inhib Med Chem
; 37(1): 51-61, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34894972
9.
Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA.
Biochemistry
; 60(8): 584-596, 2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33583181
10.
In Vivo Antibacterial Activity of Acetazolamide.
Antimicrob Agents Chemother
; 65(4)2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495225
11.
Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae.
J Enzyme Inhib Med Chem
; 36(1): 1061-1066, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34030562
12.
Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1.
Molecules
; 26(5)2021 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33668938
13.
Development of Ubiquitin Variants with Selectivity for Ubiquitin C-Terminal Hydrolase Deubiquitinases.
Biochemistry
; 59(37): 3447-3462, 2020 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32865982
14.
Ubiquitin C-Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine-Based Inhibitor.
Chembiochem
; 21(5): 712-722, 2020 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31449350
15.
Congruent Release of Drug and Polymer from Amorphous Solid Dispersions: Insights into the Role of Drug-Polymer Hydrogen Bonding, Surface Crystallization, and Glass Transition.
Mol Pharm
; 17(4): 1261-1275, 2020 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32134677
16.
Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.
Nat Chem Biol
; 12(12): 1023-1030, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27694802
17.
Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids.
Bioorg Med Chem Lett
; 27(4): 755-758, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28119024
18.
Corrigendum: Ubiquitin C-Terminal Hydrolase L1: Biochemical and Cellular Characterization of a Covalent Cyanopyrrolidine-Based Inhibitor.
Chembiochem
; 21(18): 2701, 2020 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32931129
19.
Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold.
Bioorg Med Chem Lett
; 24(16): 3968-73, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25017033
20.
Biochemical pharmacology of adenylyl cyclases in cancer.
Biochem Pharmacol
; : 116160, 2024 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38522554