Detalhe da pesquisa
1.
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis.
Nat Med
; 11(7): 757-64, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15980866
2.
Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.
Proc Natl Acad Sci U S A
; 105(34): 12319-24, 2008 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-18713856
3.
T1DBase: integration and presentation of complex data for type 1 diabetes research.
Nucleic Acids Res
; 35(Database issue): D742-6, 2007 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-17169983
4.
The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity.
J Clin Invest
; 111(1): 91-8, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12511592
5.
T1DBase, a community web-based resource for type 1 diabetes research.
Nucleic Acids Res
; 33(Database issue): D544-9, 2005 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15608258
6.
Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells.
Diabetes
; 54(8): 2396-403, 2005 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16046307
7.
Essential role of chicken ovalbumin upstream promoter-transcription factor II in insulin secretion and insulin sensitivity revealed by conditional gene knockout.
Diabetes
; 54(5): 1357-63, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15855320
8.
Glucose-regulated gene expression maintaining the glucose-responsive state of beta-cells.
Diabetes
; 51 Suppl 3: S326-32, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12475771
9.
Critical role for cataplerosis via citrate in glucose-regulated insulin release.
Diabetes
; 51(7): 2018-24, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12086928
10.
Development of a peptide-functionalized imaging nanoprobe for the targeting of (FXYD2)γa as a highly specific biomarker of pancreatic beta cells.
Contrast Media Mol Imaging
; 10(5): 398-412, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25930968
11.
Prior in vitro exposure to GLP-1 with or without GIP can influence the subsequent beta cell responsiveness.
Biochem Pharmacol
; 68(1): 33-9, 2004 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15183115
12.
Molecular diagnostics for congenital hearing loss including 15 deafness genes using a next generation sequencing platform.
BMC Med Genomics
; 5: 17, 2012 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22607986
13.
Identification of new pancreatic beta cell targets for in vivo imaging by a systems biology approach.
Curr Pharm Des
; 16(14): 1609-18, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20146665
14.
Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.
Diabetes
; 59(2): 358-74, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19934004
15.
Detailed transcriptome atlas of the pancreatic beta cell.
BMC Med Genomics
; 2: 3, 2009 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19146692
16.
Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes.
Biochem Soc Trans
; 36(Pt 3): 321-7, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18481950
17.
Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.
Diabetes
; 57(5): 1236-45, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18223009
18.
Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis.
J Biol Chem
; 282(6): 3989-97, 2007 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17158450
19.
Proteomics analysis of cytokine-induced dysfunction and death in insulin-producing INS-1E cells: new insights into the pathways involved.
Mol Cell Proteomics
; 6(12): 2180-99, 2007 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17921177
20.
A globin in the nucleus!
J Biol Chem
; 278(33): 30417-20, 2003 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12796507