Detalhe da pesquisa
1.
Contribution of the Dynamic Intestinal Absorption Model (Diamod) to the Development of a Patient-Centric Drug Formulation.
Mol Pharm
; 20(12): 6197-6212, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37955627
2.
Effects of ranitidine (antacid), food, and formulation on the pharmacokinetics of fostamatinib: results from five phase I clinical studies.
Eur J Clin Pharmacol
; 73(2): 185-195, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27858108
3.
Justification of Drug Product Dissolution Rate and Drug Substance Particle Size Specifications Based on Absorption PBPK Modeling for Lesinurad Immediate Release Tablets.
Mol Pharm
; 13(9): 3256-69, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27438964
4.
Characterization of Aspirated Duodenal Fluids from Parkinson's Disease Patients.
Pharmaceutics
; 15(4)2023 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37111729
5.
A Critical Overview of the Biological Effects of Excipients (Part I): Impact on Gastrointestinal Absorption.
AAPS J
; 24(3): 60, 2022 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35501614
6.
Chemistry Manufacturing and Controls Development, Industry Reflections on Manufacture, and Supply of Pandemic Therapies and Vaccines.
AAPS J
; 24(6): 101, 2022 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36168002
7.
Developing Clinically Relevant Dissolution Specifications (CRDSs) for Oral Drug Products: Virtual Webinar Series.
Pharmaceutics
; 14(5)2022 May 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35631595
8.
Best Practices in the Development and Validation of Physiologically Based Biopharmaceutics Modeling. A Workshop Summary Report.
J Pharm Sci
; 110(2): 584-593, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33058891
9.
Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to Support Drug Product Quality: A Workshop Summary Report.
J Pharm Sci
; 110(2): 594-609, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33152375
10.
Co-administration of Paediatric Medicines with Food and Drinks in the Context of Their Physicochemical Properties-a Global Perspective on Practices and Recommendations.
AAPS J
; 22(2): 54, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32133550
11.
Biopharmaceutical Understanding of Excipient Variability on Drug Apparent Solubility Based on Drug Physicochemical Properties. Case Study: Superdisintegrants.
AAPS J
; 22(2): 46, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32048079
12.
Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products.
AAPS J
; 22(5): 97, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32719954
13.
Correction to: Integrated Multi-stakeholder Systems Thinking Strategy: Decision-making with Biopharmaceutics Risk Assessment Roadmap (BioRAM) to Optimize Clinical Performance of Drug Products.
AAPS J
; 23(1): 7, 2020 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33270171
14.
Impact of gastrointestinal physiology on drug absorption in special populations--An UNGAP review.
Eur J Pharm Sci
; 147: 105280, 2020 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32109493
15.
IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies.
Eur J Pharm Biopharm
; 156: 50-63, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32805361
16.
Potential for pharmaceutical excipients to impact absorption: A mechanistic review for BCS Class 1 and 3 drugs.
Eur J Pharm Biopharm
; 141: 130-138, 2019 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-31128247
17.
Developing Clinically Relevant Dissolution Specifications for Oral Drug Products-Industrial and Regulatory Perspectives.
Pharmaceutics
; 12(1)2019 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31878006
18.
Effects of Food and Antacids on Pharmacokinetics and Pharmacodynamics of Lesinurad, a Selective Urate Reabsorption Inhibitor.
Clin Pharmacol Drug Dev
; 8(5): 647-656, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30748125
19.
Impact of Acid-Reducing Agents on Gastrointestinal Physiology and Design of Biorelevant Dissolution Tests to Reflect These Changes.
J Pharm Sci
; 108(11): 3461-3477, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31265846
20.
Industry's View on Using Quality Control, Biorelevant, and Clinically Relevant Dissolution Tests for Pharmaceutical Development, Registration, and Commercialization.
J Pharm Sci
; 107(1): 34-41, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29074376