Detalhe da pesquisa
1.
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity.
EMBO J
; 40(5): e106228, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33258165
2.
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection.
EMBO J
; 38(21): e101365, 2019 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31468569
3.
Intracellular neutralisation of rotavirus by VP6-specific IgG.
PLoS Pathog
; 16(8): e1008732, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32750093
4.
TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination.
Proc Natl Acad Sci U S A
; 115(41): 10440-10445, 2018 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30209217
5.
Plasma Cells Are the Most Abundant Gluten Peptide MHC-expressing Cells in Inflamed Intestinal Tissues From Patients With Celiac Disease.
Gastroenterology
; 156(5): 1428-1439.e10, 2019 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-30593798
6.
TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity.
Immunol Rev
; 268(1): 328-39, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26497531
7.
TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity.
J Immunol
; 196(8): 3452-3459, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26962230
8.
Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions.
J Immunol
; 194(11): 5497-508, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25904551
9.
Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.
J Biol Chem
; 289(24): 17228-39, 2014 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24764301
10.
Human IgG Fc-engineering for enhanced plasma half-life, mucosal distribution and killing of cancer cells and bacteria.
Nat Commun
; 15(1): 2007, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38453922
11.
Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-life.
J Biol Chem
; 287(27): 22927-37, 2012 Jun 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-22570488
12.
Antibody blockade of Jagged1 attenuates choroidal neovascularization.
Nat Commun
; 14(1): 3109, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37253747
13.
Pharmaceutical compounding and storage of faricimab in a syringe for intravitreal injection do not impair stability and bi-specific binding properties.
Int J Retina Vitreous
; 9(1): 65, 2023 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37936232
14.
Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells.
Front Immunol
; 14: 1178817, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37346044
15.
Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models.
Science
; 379(6639): 1336-1341, 2023 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-36996217
16.
Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life.
Commun Biol
; 5(1): 832, 2022 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35982144
17.
Prevention of Fetal/Neonatal Alloimmune Thrombocytopenia in Mice: Biochemical and Cell Biological Characterization of Isoforms of a Human Monoclonal Antibody.
Immunohorizons
; 6(1): 90-103, 2022 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35074850
18.
Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?
Cells
; 11(6)2022 03 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35326398
19.
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life.
iScience
; 25(2): 103746, 2022 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35118359
20.
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge.
Sci Immunol
; 7(70): eabj1640, 2022 04 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35486676